Allison Barz Leahy Division of Oncology, Department of Pediatrics Children’s Hospital of Philadelphia Biography Publications Institution JoVE Articles Allison Barz Leahy has not added a biography. If you are Allison Barz Leahy and would like to personalize this page please email our Author Liaison for assistance. Publications Impact of Poverty and Neighborhood Opportunity on Outcomes for Children Treated with CD19-directed CAR T-cell Therapy Blood. Feb, 2023 | Pubmed ID: 36351239 Capturing the Young Child's Reports of Cancer Treatment Tolerability: Does Our Practice Reflect an Assumption That They Cannot Report? Pediatric Blood & Cancer. Jan, 2023 | Pubmed ID: 36250991 Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2022 | Pubmed ID: 35838646 Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome Patients with B-Cell ALL Receiving CAR T19 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2022 | Pubmed ID: 35705524 Unrelated Donor α/β T Cell- and B Cell-depleted HSCT for the Treatment of Pediatric Acute Leukemia Blood Advances. Feb, 2022 | Pubmed ID: 34872106 Impact of High-risk Cytogenetics on Outcomes for Children and Young Adults Receiving CD19-directed CAR T-cell Therapy Blood. Apr, 2022 | Pubmed ID: 34871373 CD19-targeted Chimeric Antigen Receptor T-cell Therapy for CNS Relapsed or Refractory Acute Lymphocytic Leukaemia: a Post-hoc Analysis of Pooled Data from Five Clinical Trials The Lancet. Haematology. Oct, 2021 | Pubmed ID: 34560014 Humanized CD19-Targeted Chimeric Antigen Receptor (CAR) T Cells in CAR-Naive and CAR-Exposed Children and Young Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2021 | Pubmed ID: 34156874 Electronic Symptom Monitoring in Pediatric Patients Hospitalized for Chemotherapy Cancer. Aug, 2021 | Pubmed ID: 33945640 Risk-Adapted Preemptive Tocilizumab to Prevent Severe Cytokine Release Syndrome After CTL019 for Pediatric B-Cell Acute Lymphoblastic Leukemia: A Prospective Clinical Trial Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Mar, 2021 | Pubmed ID: 33417474 Patient-Reported Outcomes in Pediatric Oncology: The Patient Voice As a Gold Standard JAMA Pediatrics. Nov, 2020 | Pubmed ID: 32832974 Use of Patient-Reported Outcomes to Understand & Measure the Patient Experience of Novel Cell and Gene Therapies Therapeutic Innovation & Regulatory Science. Nov, 2020 | Pubmed ID: 32572771 Mapping Child and Adolescent Self-reported Symptom Data to Clinician-reported Adverse Event Grading to Improve Pediatric Oncology Care and Research Cancer. Jan, 2020 | Pubmed ID: 31553494 Commentary on King-Kallimanis Et Al.: Inadequate Measurement of Symptomatic Adverse Events in Immunotherapy Registration Trials Clinical Trials (London, England). Jun, 2019 | Pubmed ID: 30895807 Outcome Dimensions in Pediatric Palliative Care Pediatrics. Jan, 2019 | Pubmed ID: 30530505 Occurrence of Treatment-Related Cardiotoxicity and Its Impact on Outcomes Among Children Treated in the AAML0531 Clinical Trial: A Report From the Children's Oncology Group Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jan, 2019 | Pubmed ID: 30379624 Tisagenlecleucel for the Treatment of B-cell Acute Lymphoblastic Leukemia Expert Review of Anticancer Therapy. Oct, 2018 | Pubmed ID: 30111196 Relationship Between State-Level Google Online Search Volume and Cancer Incidence in the United States: Retrospective Study Journal of Medical Internet Research. Jan, 2018 | Pubmed ID: 29311051 Symptom Monitoring in Pediatric Oncology Using Patient-Reported Outcomes: Why, How, and Where Next The Patient. Apr, 2018 | Pubmed ID: 29071524 Reply To: Medication Contaminants As a Potential Cause of Anaphylaxis to Vincristine: What About Drug Specific Antigens? Pediatric Blood & Cancer. Feb, 2018 | Pubmed ID: 29049863 Medication Contaminants As a Potential Cause of Anaphylaxis to Vincristine Pediatric Blood & Cancer. Jan, 2018 | Pubmed ID: 28834048 Advancements in CAR-T Cell Manufacturing and Gene Therapy Production (Video) | JoVE Rene Machietto1, Nicholas Giacobbe1, Jessica Perazzelli2, Ted J. Hofmann2, Allison Barz Leahy2,3, Stephan A. Grupp1,2,3, Yongping Wang1,3,4, Stephan Kadauke1,3,4 1Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, 2Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia, 3Perelman School of Medicine at the University of Pennsylvania, 4Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia JoVE 65488 Medicine
Advancements in CAR-T Cell Manufacturing and Gene Therapy Production (Video) | JoVE Rene Machietto1, Nicholas Giacobbe1, Jessica Perazzelli2, Ted J. Hofmann2, Allison Barz Leahy2,3, Stephan A. Grupp1,2,3, Yongping Wang1,3,4, Stephan Kadauke1,3,4 1Cell and Gene Therapy Laboratory, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, 2Division of Oncology, Department of Pediatrics, Children’s Hospital of Philadelphia, 3Perelman School of Medicine at the University of Pennsylvania, 4Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia JoVE 65488 Medicine