Anna Capasso Medicine University of Colorado Denver Anschutz Medical Campus Biography Publications Institution JoVE Articles Anna Capasso has not added a biography. If you are Anna Capasso and would like to personalize this page please email our Author Liaison for assistance. Publications Antitumor Activity of the Aurora a Selective Kinase Inhibitor, Alisertib, Against Preclinical Models of Colorectal Cancer Oncotarget. Jul, 2016 | Pubmed ID: 27385211 The Novel Tankyrase Inhibitor (AZ1366) Enhances Irinotecan Activity in Tumors That Exhibit Elevated Tankyrase and Irinotecan Resistance Oncotarget. May, 2016 | Pubmed ID: 27070088 Cannabinoids for the Treatment of Schizophrenia: An Overview Current Topics in Medicinal Chemistry. 2016 | Pubmed ID: 26845552 The Changing Landscape of Phase I Trials in Oncology Nature Reviews. Clinical Oncology. Feb, 2016 | Pubmed ID: 26552953 Effect of Docosahexaenoic Acid on Cell Cycle Pathways in Breast Cell Lines With Different Transformation Degree Journal of Cellular Physiology. Jun, 2016 | Pubmed ID: 26480024 The Changing Landscape of Phase I Trials in Oncology American Society of Clinical Oncology Educational Book / ASCO. American Society of Clinical Oncology. Meeting. 2015 | Pubmed ID: 25993134 (6-bromo-1,4-dimethyl-9H-carbazol-3-yl-methylene)-hydrazine (carbhydraz) Acts As a GPER Agonist in Breast Cancer Cells Current Topics in Medicinal Chemistry. 2015 | Pubmed ID: 25786510 Crystallographic Study and Biological Evaluation of 1,4-dimethyl-N-alkylcarbazoles Current Topics in Medicinal Chemistry. 2015 | Pubmed ID: 25786507 Primary and Acquired Resistance of Colorectal Cancer Cells to Anti-EGFR Antibodies Converge on MEK/ERK Pathway Activation and Can Be Overcome by Combined MEK/EGFR Inhibition Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2014 | Pubmed ID: 24812410 Cycloartane Glycosides from Astragalus Plumosus Var. Krugianus and Evaluation of Their Antioxidant Potential Fitoterapia. Jan, 2014 | Pubmed ID: 24216051 Steroidal Glycosides with Antiproliferative Activities from Digitalis Trojana Phytotherapy Research : PTR. Apr, 2014 | Pubmed ID: 23722601 Increased TGF-α As a Mechanism of Acquired Resistance to the Anti-EGFR Inhibitor Cetuximab Through EGFR-MET Interaction and Activation of MET Signaling in Colon Cancer Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2013 | Pubmed ID: 24122793 Antipsychotic Drugs Opposite to Metabolic Risk: Neurotransmitters, Neurohormonal and Pharmacogenetic Mechanisms Underlying with Weight Gain and Metabolic Syndrome The Open Neurology Journal. 2013 | Pubmed ID: 23894259 Agomelatine Efficacy in the Night Eating Syndrome Case Reports in Medicine. 2013 | Pubmed ID: 23762076 Cyclohexa-2,5-diene-1,4-dione-based Antiproliferative Agents: Design, Synthesis, and Cytotoxic Evaluation Journal of Experimental & Clinical Cancer Research : CR. 2013 | Pubmed ID: 23631805 Antitumor Activity of Pimasertib, a Selective MEK 1/2 Inhibitor, in Combination with PI3K/mTOR Inhibitors or with Multi-targeted Kinase Inhibitors in Pimasertib-resistant Human Lung and Colorectal Cancer Cells International Journal of Cancer. Nov, 2013 | Pubmed ID: 23629727 Targeted Approach to Metastatic Colorectal Cancer: What Comes Beyond Epidermal Growth Factor Receptor Antibodies and Bevacizumab? Therapeutic Advances in Medical Oncology. Jan, 2013 | Pubmed ID: 23323147 Antioxidant Action and Therapeutic Efficacy of Allium Sativum L Molecules (Basel, Switzerland). 2013 | Pubmed ID: 23292331 Enhanced Brain Performance in Mice Following Postnatal Stress The Journal of Endocrinology. Dec, 2012 | Pubmed ID: 23045190 Migraine and Genetic Polymorphisms: an Overview The Open Neurology Journal. 2012 | Pubmed ID: 22962564 Role of Lipid Rafts/caveolae in the Anticancer Effect of Endocannabinoids Mini Reviews in Medicinal Chemistry. Oct, 2012 | Pubmed ID: 22625418 Vinorelbine in Cancer Therapy Current Drug Targets. Jul, 2012 | Pubmed ID: 22594474 Antiproliferative Steroidal Glycosides from Digitalis Ciliata Fitoterapia. Apr, 2012 | Pubmed ID: 22245088 Night Eating Syndrome: an Overview The Journal of Pharmacy and Pharmacology. Jan, 2012 | Pubmed ID: 22150667 Cycloartane Glycosides from Astragalus Stereocalyx Bornm Phytochemistry. Jan, 2012 | Pubmed ID: 22033014 Iridoid, Phenylethanoid and Flavonoid Glycosides from Sideritis Trojana Fitoterapia. Jan, 2012 | Pubmed ID: 22024633 Efficacy and Tolerability of Vinorelbine in the Cancer Therapy Current Drug Safety. Jul, 2011 | Pubmed ID: 22122393 Xanthohumol Induces Apoptosis in Human Malignant Glioblastoma Cells by Increasing Reactive Oxygen Species and Activating MAPK Pathways Journal of Natural Products. Dec, 2011 | Pubmed ID: 22111577 Triterpenoid Constituents from the Roots of Paeonia Rockii Ssp. Rockii Journal of Natural Products. Oct, 2011 | Pubmed ID: 21954959 Duloxetine in the Treatment of Depression: an Overview Central Nervous System Agents in Medicinal Chemistry. Sep, 2011 | Pubmed ID: 21919872 Interconverting Flavanone Glucosides and Other Phenolic Compounds in Lippia Salviaefolia Cham. Ethanol Extracts Phytochemistry. Nov, 2011 | Pubmed ID: 21871644 Neuroinflamm-aging and Neurodegenerative Diseases: an Overview CNS & Neurological Disorders Drug Targets. Aug, 2011 | Pubmed ID: 21631404 Neuroinflammation and Ageing: Current Theories and an Overview of the Data Reviews on Recent Clinical Trials. Sep, 2011 | Pubmed ID: 21241238 Xolair in Asthma Therapy: an Overview Inflammation & Allergy Drug Targets. Feb, 2011 | Pubmed ID: 21184647 Recent Clinical Aspects of Hyperprolactinemia Induced by Antipsychotics Reviews on Recent Clinical Trials. Jan, 2011 | Pubmed ID: 20868350 Genomic and Proteomic Approaches to Renal Cell Carcinoma Journal of Nephrology. Mar-Apr, 2011 | Pubmed ID: 20437403 Sesquiterpene Coumarins from Ferula Gumosa Journal of Natural Products. Nov, 2010 | Pubmed ID: 20961138 Synergistic Antitumor Activity of Sorafenib in Combination with Epidermal Growth Factor Receptor Inhibitors in Colorectal and Lung Cancer Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2010 | Pubmed ID: 20810384 Post-natal Stress-induced Endocrine and Metabolic Alterations in Mice at Adulthood Involve Different Pro-opiomelanocortin-derived Peptides Peptides. Nov, 2010 | Pubmed ID: 20727932 Potential Therapeutic Effects of Vitamin E and C on Placental Oxidative Stress Induced by Nicotine: an in Vitro Evidence The Open Biochemistry Journal. 2010 | Pubmed ID: 20676222 Sexual Dimorphic Evolution of Metabolic Programming in Non-genetic Non-alimentary Mild Metabolic Syndrome Model in Mice Depends on Feed-back Mechanisms Integrity for Pro-opiomelanocortin-derived Endogenous Substances Peptides. Aug, 2010 | Pubmed ID: 20493223 Enhanced Eryptosis of Erythrocytes from Gene-targeted Mice Lacking Annexin A7 Pflügers Archiv : European Journal of Physiology. Aug, 2010 | Pubmed ID: 20490540 Rapamycin-induced Phosphaturia Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Sep, 2010 | Pubmed ID: 20368307 Saponins and Polyphenols from Fadogia Ancylantha (makoni Tea) Journal of Natural Products. Feb, 2010 | Pubmed ID: 20058934 Detecting the Surface Localization and Cytoplasmic Cleavage of Membrane-bound Proteins Methods in Cell Biology. 2009 | Pubmed ID: 20362093 Molecules Acting on CB1 Receptor and Their Effects on Morphine Withdrawal In Vitro The Open Biochemistry Journal. 2009 | Pubmed ID: 20111725 Migraine: an Overview The Open Neurology Journal. 2009 | Pubmed ID: 19888434 AMP-activated Protein Kinase: a Physiological off Switch for Murine Gastric Acid Secretion Pflügers Archiv : European Journal of Physiology. Nov, 2009 | Pubmed ID: 19621238 Neurobiology of Pain in Children: an Overview The Open Biochemistry Journal. 2009 | Pubmed ID: 19543535 Functional Interaction Between Purinergic System and Opioid Withdrawal: in Vitro Evidence Current Drug Safety. May, 2009 | Pubmed ID: 19442100 Beta-endorphin Fragments DTgammaE and DEgammaE Reduced Morphine Inhibition of Electrically-induced Contractions and Opiate Withdrawal Medicinal Chemistry (Shāriqah (United Arab Emirates)). Mar, 2009 | Pubmed ID: 19275715 Recent Clinical Aspects of Eating Disorders Reviews on Recent Clinical Trials. Jan, 2009 | Pubmed ID: 19149764 Pharmacological Profile of SSRIs and SNRIs in the Treatment of Eating Disorders Current Clinical Pharmacology. Jan, 2009 | Pubmed ID: 19149506 The Effects of the 3,4-methylenedioxymethamphetamine (Ecstasy) in Some Cerebral Areas: Role of the Oxidative Stress Drug Metabolism Letters. Apr, 2008 | Pubmed ID: 19356078 Effects of Vitamin E and C on Placental Oxidative Stress: an in Vitro Evidence for the Potential Therapeutic or Prophylactic Treatment of Preeclampsia Medicinal Chemistry (Shāriqah (United Arab Emirates)). Nov, 2008 | Pubmed ID: 18991735 The Involvement of Prostaglandins and Nitric Oxide in the Development of Brain Excitability: a Relationship Study Current Medicinal Chemistry. 2008 | Pubmed ID: 18855675 Methisergide Selective Inhibition of Opioid Acute Physical Dependence in Isolated Tissues Medicinal Chemistry (Shāriqah (United Arab Emirates)). Jul, 2008 | Pubmed ID: 18673141 Functional Interference of Dexamethasone on Some Morphine Effects: Hypothesis for the Steroid-opioid Interaction Recent Patents on CNS Drug Discovery. Jun, 2008 | Pubmed ID: 18537773 The Beta-lactam Antibiotic Ceftriaxone Inhibits Physical Dependence and Abstinence-induced Withdrawal from Cocaine, Amphetamine, Methamphetamine, and Clorazepate in Planarians European Journal of Pharmacology. Apr, 2008 | Pubmed ID: 18342307 Glucocorticoids Involvement in the Control of CNS Excitability Recent Patents on CNS Drug Discovery. Jun, 2007 | Pubmed ID: 18221228 In Vitro Binding Receptors Study by Valeriana Adscendens, Iresine Herbstii and Brugmansia Arborea Extracts Medicinal Chemistry (Shāriqah (United Arab Emirates)). Nov, 2007 | Pubmed ID: 18045210 Bioactivity of New Mu and Delta Opioid Peptides Medicinal Chemistry (Shāriqah (United Arab Emirates)). Sep, 2007 | Pubmed ID: 17897075 The Effect of Flavonol Glycosides on Opiate Withdrawal Medicinal Chemistry (Shāriqah (United Arab Emirates)). Jul, 2007 | Pubmed ID: 17627569 Evaluation of Antioxidative Properties of Allium Species Growing Wild in Italy Phytotherapy Research : PTR. Sep, 2007 | Pubmed ID: 17514631 Flumazenil-sensitive Dose-related Physical Dependence in Planarians Produced by Two Benzodiazepine and One Non-benzodiazepine Benzodiazepine-receptor Agonists European Journal of Pharmacology. Jun, 2007 | Pubmed ID: 17368613 Differential Effects of Three Species of Hypericum in an Open Field Test Phytotherapy Research : PTR. Mar, 2007 | Pubmed ID: 17160972 Administration of Antisense Oligonucleotide Against Pro-opiomelanocortin Prevents Enduring Hormonal Alterations Induced by Neonatal Handling in Male Mice European Journal of Pharmacology. Nov, 2006 | Pubmed ID: 17045988 Binding Studies for Serotoninergic, Dopaminergic and Noradrenergic Receptors of Valeriana Adscendens Trel. Extracts Journal of Ethnopharmacology. Nov, 2006 | Pubmed ID: 16839726 In Vitro Antiproliferative Effect of Six Salvia Species on Human Tumor Cell Lines Phytotherapy Research : PTR. Aug, 2006 | Pubmed ID: 16676297 Affinity of Iresine Herbstii and Brugmansia Arborea Extracts on Different Cerebral Receptors Journal of Ethnopharmacology. May, 2006 | Pubmed ID: 16406412 Neurophysiological Studies of Heteropteris Glabra Hok. & Arn. (Malpighiaceae) in DBA/2J Mice Journal of Ethnopharmacology. Mar, 2005 | Pubmed ID: 15740875 Food and Red Wine Do Not Exert Acute Effects on Vascular Reactivity Metabolism: Clinical and Experimental. Aug, 2004 | Pubmed ID: 15281023 Alkaloids from Brugmansia Arborea (L.) Lagerhein Reduce Morphine Withdrawal in Vitro Phytotherapy Research : PTR. Aug, 2003 | Pubmed ID: 12916089 The Effect of Papaverine on Acute Opiate Withdrawal in Guinea Pig Ileum Phytotherapy Research : PTR. Aug, 2003 | Pubmed ID: 12916076 Petrosaspongiolide M Reduces Morphine Withdrawal in Vitro Life Sciences. Jun, 2003 | Pubmed ID: 12770615 Alpha2-adrenoceptor Antagonist SL 84.0418 Reduces the Expression of Neocortical Spike-and-wave Spindling Episodes in DBA/2J Mice Progress in Neuro-psychopharmacology & Biological Psychiatry. Feb, 2003 | Pubmed ID: 12551737 Vas Deferens Response to Selective Opioid Receptor Agonists in Adult Mice is Impaired Following Postnatal Repeated Mild Stress European Journal of Pharmacology. Jan, 2003 | Pubmed ID: 12498927 Pharmacological Studies and Synthesis of Morpholino Alkyl Derivatives Chemical & Pharmaceutical Bulletin. Sep, 2002 | Pubmed ID: 12237528 Dexamethasone Reduces Morphine-induced Straub Reaction in Mice The Journal of Pharmacy and Pharmacology. Jul, 2002 | Pubmed ID: 12162718 Beta-endorphin Fragments (DT Gamma E and DE Gamma E) Reduce Opiate Withdrawal in Guinea Pig Ileum Progress in Neuro-psychopharmacology & Biological Psychiatry. Feb, 2002 | Pubmed ID: 11817510 Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies Stacey Bagby1, Wells A. Messersmith1, Todd M. Pitts1, Anna Capasso1, Marileila Varella-Garcia1, Peter J. Klauck1, Jihye Kim1, Aik-Choon Tan1, S. Gail Eckhardt1, John J. Tentler1, John Arcaroli1 1Medicine, University of Colorado Denver Anschutz Medical Campus JoVE 54393 Cancer Research
Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies Stacey Bagby1, Wells A. Messersmith1, Todd M. Pitts1, Anna Capasso1, Marileila Varella-Garcia1, Peter J. Klauck1, Jihye Kim1, Aik-Choon Tan1, S. Gail Eckhardt1, John J. Tentler1, John Arcaroli1 1Medicine, University of Colorado Denver Anschutz Medical Campus JoVE 54393 Cancer Research