Carl G. Figdor Department of Medical BioSciences Radboudumc Biography Publications Institution JoVE Articles Carl G. Figdor has not added a biography. If you are Carl G. Figdor and would like to personalize this page please email our Author Liaison for assistance. Publications Tumor Microenvironment Shows an Immunological Abscopal Effect in Patients with NSCLC Treated with Pembrolizumab-radiotherapy Combination Journal for Immunotherapy of Cancer. Oct, 2022 | Pubmed ID: 36252995 Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody International Journal of Molecular Sciences. Aug, 2022 | Pubmed ID: 35955841 Correction To: Multiscale Imaging of Therapeutic Anti-PD-L1 Antibody Localization Using Molecularly Defined Imaging Agents Iris Journal of Nanobiotechnology. May, 2022 | Pubmed ID: 35568872 Paired Primary and Metastatic Lesions of Patients with Ipilimumab-treated Melanoma: High Variation in Lymphocyte Infiltration and HLA-ABC Expression Whereas Tumor Mutational Load is Similar and Correlates with Clinical Outcome Journal for Immunotherapy of Cancer. May, 2022 | Pubmed ID: 35550553 Efficient Targeting of NY-ESO-1 Tumor Antigen to Human CDC1s by Lymphotactin Results in Cross-presentation and Antigen-specific T Cell Expansion Journal for Immunotherapy of Cancer. Apr, 2022 | Pubmed ID: 35428705 Multiscale Imaging of Therapeutic Anti-PD-L1 Antibody Localization Using Molecularly Defined Imaging Agents Journal of Nanobiotechnology. Feb, 2022 | Pubmed ID: 35109860 Assessing the Safety, Tolerability and Efficacy of PLGA-based Immunomodulatory Nanoparticles in Patients with Advanced NY-ESO-1-positive Cancers: a First-in-human Phase I Open-label Dose-escalation Study Protocol BMJ Open. Nov, 2021 | Pubmed ID: 34848513 Robust Antigen-Specific T Cell Activation Within Injectable 3D Synthetic Nanovaccine Depots ACS Biomaterials Science & Engineering. Dec, 2021 | Pubmed ID: 34734689 In Vivo PET Imaging of Monocytes Labeled with [Zr]Zr-PLGA-NH Nanoparticles in Tumor and Infection Models Cancers. Oct, 2021 | Pubmed ID: 34680219 Cytotoxic T Cells Are Able to Efficiently Eliminate Cancer Cells by Additive Cytotoxicity Nature Communications. Sep, 2021 | Pubmed ID: 34471116 Metabolic Screening of Cytotoxic T-cell Effector Function Reveals the Role of CRAC Channels in Regulating Lethal Hit Delivery Cancer Immunology Research. Aug, 2021 | Pubmed ID: 34226201 Characterization of Intrinsically Radiolabeled Poly(lactic--glycolic Acid) Nanoparticles for Ex Vivo Autologous Cell Labeling and in Vivo Tracking Bioconjugate Chemistry. Aug, 2021 | Pubmed ID: 34161070 PLGA-based Nanomedicines Manufacturing: Technologies Overview and Challenges in Industrial Scale-up International Journal of Pharmaceutics. Aug, 2021 | Pubmed ID: 34144133 A Tipping Point in Cancer-immune Dynamics Leads to Divergent Immunotherapy Responses and Hampers Biomarker Discovery Journal for Immunotherapy of Cancer. May, 2021 | Pubmed ID: 34059522 Three Distinct Tolerogenic CD14 Myeloid Cell Types to Actively Manage Autoimmune Disease: Opportunities and Challenges Journal of Autoimmunity. Jun, 2021 | Pubmed ID: 33901801 Semiflexible Immunobrushes Induce Enhanced T Cell Activation and Expansion ACS Applied Materials & Interfaces. Apr, 2021 | Pubmed ID: 33797875 PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses Frontiers in Immunology. 2021 | Pubmed ID: 33717196 Human Type 1 and Type 2 Conventional Dendritic Cells Express Indoleamine 2,3-dioxygenase 1 with Functional Effects on T Cell Priming European Journal of Immunology. Jun, 2021 | Pubmed ID: 33675038 Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering Bioconjugate Chemistry. Feb, 2021 | Pubmed ID: 33476135 Nanovaccine Administration Route is Critical to Obtain Pertinent INKt Cell Help for Robust Anti-tumor T and B Cell Responses Oncoimmunology. Mar, 2020 | Pubmed ID: 33457086 High Health-Related Quality of Life During Dendritic Cell Vaccination Therapy in Patients With Castration-Resistant Prostate Cancer Frontiers in Oncology. 2020 | Pubmed ID: 33194595 Collective Invasion Induced by an Autocrine Purinergic Loop Through Connexin-43 Hemichannels The Journal of Cell Biology. Oct, 2020 | Pubmed ID: 32777015 The Tumour Microenvironment Shapes Dendritic Cell Plasticity in a Human Organotypic Melanoma Culture Nature Communications. Jun, 2020 | Pubmed ID: 32488012 Autologous Monocyte-derived DC Vaccination Combined with Cisplatin in Stage III and IV Melanoma Patients: a Prospective, Randomized Phase 2 Trial Cancer Immunology, Immunotherapy : CII. Mar, 2020 | Pubmed ID: 31980913 Multicore Liquid Perfluorocarbon-Loaded Multimodal Nanoparticles for Stable Ultrasound and F MRI Applied to In Vivo Cell Tracking Advanced Functional Materials. May, 2019 | Pubmed ID: 32132881 Cross-talk Between INKT Cells and CD8 T Cells in the Spleen Requires the IL-4/CCL17 Axis for the Generation of Short-lived Effector Cells Proceedings of the National Academy of Sciences of the United States of America. Dec, 2019 | Pubmed ID: 31796596 Intracellular Galectin-9 Controls Dendritic Cell Function by Maintaining Plasma Membrane Rigidity IScience. Dec, 2019 | Pubmed ID: 31786520 Blood-derived Dendritic Cell Vaccinations Induce Immune Responses That Correlate with Clinical Outcome in Patients with Chemo-naive Castration-resistant Prostate Cancer Journal for Immunotherapy of Cancer. Nov, 2019 | Pubmed ID: 31727154 Microfluidics-Assisted Size Tuning and Biological Evaluation of PLGA Particles Pharmaceutics. Nov, 2019 | Pubmed ID: 31717354 Imaging of T-cells and Their Responses During Anti-cancer Immunotherapy Theranostics. Oct, 2019 | Pubmed ID: 31656546 Functional Diversification of Hybridoma-produced Antibodies by CRISPR/HDR Genomic Engineering Science Advances. Aug, 2019 | Pubmed ID: 31489367 Synthetic Semiflexible and Bioactive Brushes Biomacromolecules. Jul, 2019 | Pubmed ID: 31150222 Biomaterial-Based Activation and Expansion of Tumor-Specific T Cells Frontiers in Immunology. 2019 | Pubmed ID: 31130945 ICAM3-Fc Outperforms Receptor-Specific Antibodies Targeted Nanoparticles to Dendritic Cells for Cross-Presentation Molecules (Basel, Switzerland). May, 2019 | Pubmed ID: 31083610 Attacking Tumors From All Sides: Personalized Multiplex Vaccines to Tackle Intratumor Heterogeneity Frontiers in Immunology. 2019 | Pubmed ID: 31040852 Design of Triphasic Poly(lactic--glycolic Acid) Nanoparticles Containing a Perfluorocarbon Phase for Biomedical Applications RSC Advances. Feb, 2018 | Pubmed ID: 35540375 Injectable Biomimetic Hydrogels As Tools for Efficient T Cell Expansion and Delivery Frontiers in Immunology. 2018 | Pubmed ID: 30546367 Biophysical Characterization of CD6-TCR/CD3 Interplay in T Cells Frontiers in Immunology. 2018 | Pubmed ID: 30356797 C-type Lectin-like Receptor 2 (CLEC-2)-dependent Dendritic Cell Migration is Controlled by Tetraspanin CD37 Journal of Cell Science. Oct, 2018 | Pubmed ID: 30185523 A Comparative Assessment of Continuous Production Techniques to Generate Sub-micron Size PLGA Particles International Journal of Pharmaceutics. Oct, 2018 | Pubmed ID: 30144511 Dendritic Cells in Cancer Immunotherapy Nature Materials. Jun, 2018 | Pubmed ID: 29795222 Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules Within the Tumor Microenvironment Journal of Immunology (Baltimore, Md. : 1950). Jan, 2018 | Pubmed ID: 29141863 Migrating into the Tumor: a Roadmap for T Cells Trends in Cancer. Nov, 2017 | Pubmed ID: 29120755 N-glycan Mediated Adhesion Strengthening During Pathogen-receptor Binding Revealed by Cell-cell Force Spectroscopy Scientific Reports. Jul, 2017 | Pubmed ID: 28751750 Harnessing RNA Sequencing for Global, Unbiased Evaluation of Two New Adjuvants for Dendritic-cell Immunotherapy Oncotarget. Mar, 2017 | Pubmed ID: 28186996 Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function Cell Reports. Sep, 2016 | Pubmed ID: 27626665 Ipilimumab Administered to Metastatic Melanoma Patients Who Progressed After Dendritic Cell Vaccination Oncoimmunology. Aug, 2016 | Pubmed ID: 27622070 Human CD1c(+) DCs Are Critical Cellular Mediators of Immune Responses Induced by Immunogenic Cell Death Oncoimmunology. Aug, 2016 | Pubmed ID: 27622063 Adjuvant Dendritic Cell Vaccination Induces Tumor-specific Immune Responses in the Majority of Stage III Melanoma Patients Oncoimmunology. Jul, 2016 | Pubmed ID: 27622047 Adjuvant Dendritic Cell Vaccination in High-Risk Uveal Melanoma Ophthalmology. Oct, 2016 | Pubmed ID: 27476772 Expansion of a BDCA1+CD14+ Myeloid Cell Population in Melanoma Patients May Attenuate the Efficacy of Dendritic Cell Vaccines Cancer Research. Aug, 2016 | Pubmed ID: 27325645 Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients Journal of Immunotherapy (Hagerstown, Md. : 1997). 2016 | Pubmed ID: 27227325 T-cell Landscape in a Primary Melanoma Predicts the Survival of Patients with Metastatic Disease After Their Treatment with Dendritic Cell Vaccines Cancer Research. Jun, 2016 | Pubmed ID: 27197179 Dendritic Cell-Based Immunotherapy: State of the Art and Beyond Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2016 | Pubmed ID: 27084743 Preclinical Exploration of Combining Plasmacytoid and Myeloid Dendritic Cell Vaccination with BRAF Inhibition Journal of Translational Medicine. Apr, 2016 | Pubmed ID: 27075584 Opportunities for Immunotherapy in Microsatellite Instable Colorectal Cancer Cancer Immunology, Immunotherapy : CII. Oct, 2016 | Pubmed ID: 27060000 A Comparative Study of the T Cell Stimulatory and Polarizing Capacity of Human Primary Blood Dendritic Cell Subsets Mediators of Inflammation. 2016 | Pubmed ID: 27057096 Co-delivery of PLGA Encapsulated Invariant NKT Cell Agonist with Antigenic Protein Induce Strong T Cell-mediated Antitumor Immune Responses Oncoimmunology. 2016 | Pubmed ID: 26942088 Long-lasting Multifunctional CD8 T Cell Responses in End-stage Melanoma Patients Can Be Induced by Dendritic Cell Vaccination Oncoimmunology. 2016 | Pubmed ID: 26942087 Favorable Overall Survival in Stage III Melanoma Patients After Adjuvant Dendritic Cell Vaccination Oncoimmunology. 2016 | Pubmed ID: 26942068 Proteome Based Construction of the Lymphocyte Function-Associated Antigen 1 (LFA-1) Interactome in Human Dendritic Cells PloS One. 2016 | Pubmed ID: 26889827 Prophylactic Vaccines Are Potent Activators of Monocyte-derived Dendritic Cells and Drive Effective Anti-tumor Responses in Melanoma Patients at the Cost of Toxicity Cancer Immunology, Immunotherapy : CII. Mar, 2016 | Pubmed ID: 26861670 Tetraspanin CD37 Protects Against the Development of B Cell Lymphoma The Journal of Clinical Investigation. Feb, 2016 | Pubmed ID: 26784544 Effective Clinical Responses in Metastatic Melanoma Patients After Vaccination with Primary Myeloid Dendritic Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2016 | Pubmed ID: 26712687 Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration Journal of Immunology (Baltimore, Md. : 1950). Jan, 2016 | Pubmed ID: 26597008 Intranodal Vaccination with MRNA-optimized Dendritic Cells in Metastatic Melanoma Patients Oncoimmunology. Aug, 2015 | Pubmed ID: 26405571 Design of a Highly Selective Quenched Activity-based Probe and Its Application in Dual Color Imaging Studies of Cathepsin S Activity Localization Journal of the American Chemical Society. Apr, 2015 | Pubmed ID: 25785540 Restoring Immunosurveillance by Dendritic Cell Vaccines and Manipulation of the Tumor Microenvironment Immunobiology. Feb, 2015 | Pubmed ID: 25466585 Tumoricidal Activity of Human Dendritic Cells Trends in Immunology. Nov, 2013 | Pubmed ID: 24262387 Probing Cellular Heterogeneity in Cytokine-secreting Immune Cells Using Droplet-based Microfluidics Lab on a Chip. Nov, 2013 | Pubmed ID: 24185478 Aiming to Immune Elimination of Ovarian Cancer Stem Cells World Journal of Stem Cells. Oct, 2013 | Pubmed ID: 24179603 Targeting Uptake Receptors on Human Plasmacytoid Dendritic Cells Triggers Antigen Cross-presentation and Robust Type I IFN Secretion Journal of Immunology (Baltimore, Md. : 1950). Nov, 2013 | Pubmed ID: 24127556 Reducing Cell Number Improves the Homing of Dendritic Cells to Lymph Nodes Upon Intradermal Vaccination Oncoimmunology. Jul, 2013 | Pubmed ID: 24073362 The Stem Cell Markers Oct4A, Nanog and C-Myc Are Expressed in Ascites Cells and Tumor Tissue of Ovarian Cancer Patients Cellular Oncology (Dordrecht). Oct, 2013 | Pubmed ID: 23928726 Importance of Helper T-cell Activation in Dendritic Cell-based Anticancer Immunotherapy Oncoimmunology. Jun, 2013 | Pubmed ID: 23894702 Naturally Circulating Dendritic Cells to Vaccinate Cancer Patients Oncoimmunology. Mar, 2013 | Pubmed ID: 23802086 Physical Limits of Cell Migration: Control by ECM Space and Nuclear Deformation and Tuning by Proteolysis and Traction Force The Journal of Cell Biology. Jun, 2013 | Pubmed ID: 23798731 Functional OCT4-specific CD4(+) and CD8(+) T Cells in Healthy Controls and Ovarian Cancer Patients Oncoimmunology. May, 2013 | Pubmed ID: 23762805 Dendritic Cell-based Nanovaccines for Cancer Immunotherapy Current Opinion in Immunology. Jun, 2013 | Pubmed ID: 23571027 The Nature of Activatory and Tolerogenic Dendritic Cell-derived Signal II Frontiers in Immunology. 2013 | Pubmed ID: 23450201 Targeting Dendritic Cells--why Bother? Blood. Apr, 2013 | Pubmed ID: 23390195 Targeting of 111In-labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2013 | Pubmed ID: 23382117 Automated Podosome Identification and Characterization in Fluorescence Microscopy Images Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. Feb, 2013 | Pubmed ID: 23347434 Natural Human Plasmacytoid Dendritic Cells Induce Antigen-specific T-cell Responses in Melanoma Patients Cancer Research. Feb, 2013 | Pubmed ID: 23345163 Human Plasmacytoid Dendritic Cells Efficiently Cross-present Exogenous Ags to CD8+ T Cells Despite Lower Ag Uptake Than Myeloid Dendritic Cell Subsets Blood. Jan, 2013 | Pubmed ID: 23212525 Targeting CD4(+) T-helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell-based Vaccination Cancer Research. Jan, 2013 | Pubmed ID: 23087058 ALCAM/CD166 Adhesive Function is Regulated by the Tetraspanin CD9 Cellular and Molecular Life Sciences : CMLS. Feb, 2013 | Pubmed ID: 23052204 The Tetraspanin CD37 Orchestrates the α(4)β(1) Integrin-Akt Signaling Axis and Supports Long-lived Plasma Cell Survival Science Signaling. Nov, 2012 | Pubmed ID: 23150881 Enhancing Immunogenicity and Cross-reactivity of HIV-1 Antigens by in Vivo Targeting to Dendritic Cells Nanomedicine (London, England). Oct, 2012 | Pubmed ID: 23148541 In Vivo Tracking Techniques for Cellular Regeneration, Replacement, and Redirection Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Dec, 2012 | Pubmed ID: 23143090 In Vivo Imaging of Therapy-induced Anti-cancer Immune Responses in Humans Cellular and Molecular Life Sciences : CMLS. Oct, 2012 | Pubmed ID: 23052208 The Neck Region of the C-type Lectin DC-SIGN Regulates Its Surface Spatiotemporal Organization and Virus-binding Capacity on Antigen-presenting Cells The Journal of Biological Chemistry. Nov, 2012 | Pubmed ID: 23019323 Skin-test Infiltrating Lymphocytes Early Predict Clinical Outcome of Dendritic Cell-based Vaccination in Metastatic Melanoma Cancer Research. Dec, 2012 | Pubmed ID: 23010076 Human Plasmacytoid Dendritic Cells Are Equipped with Antigen-presenting and Tumoricidal Capacities Blood. Nov, 2012 | Pubmed ID: 22966165 Labeling Cells for in Vivo Tracking Using (19)F MRI Biomaterials. Dec, 2012 | Pubmed ID: 22959182 Insight into the Dynamics, Localization and Magnitude of Antigen-specific Immune Responses by [(18)F]FLT PET Imaging Oncoimmunology. Aug, 2012 | Pubmed ID: 22934268 Vaccination with MRNA-electroporated Dendritic Cells Induces Robust Tumor Antigen-specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2012 | Pubmed ID: 22896657 The Modular Nature of Dendritic Cell Responses to Commensal and Pathogenic Fungi PloS One. 2012 | Pubmed ID: 22879980 Antibodies and Carbohydrate Ligands Binding to DC-SIGN Differentially Modulate Receptor Trafficking European Journal of Immunology. Aug, 2012 | Pubmed ID: 22653683 Targeting Nanoparticles to Dendritic Cells for Immunotherapy Methods in Enzymology. 2012 | Pubmed ID: 22568905 Lateral Mobility of Individual Integrin Nanoclusters Orchestrates the Onset for Leukocyte Adhesion Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22411821 Comparison of Antibodies and Carbohydrates to Target Vaccines to Human Dendritic Cells Via DC-SIGN Biomaterials. Jun, 2012 | Pubmed ID: 22410170 Harnessing Human Plasmacytoid Dendritic Cells As Professional APCs Cancer Immunology, Immunotherapy : CII. Aug, 2012 | Pubmed ID: 22294456 The C-type Lectin Receptor CLEC9A Mediates Antigen Uptake and (cross-)presentation by Human Blood BDCA3+ Myeloid Dendritic Cells Blood. Mar, 2012 | Pubmed ID: 22234694 Regulatory T Cells in Melanoma: the Final Hurdle Towards Effective Immunotherapy? The Lancet Oncology. Jan, 2012 | Pubmed ID: 22225723 Geometry Sensing by Dendritic Cells Dictates Spatial Organization and PGE(2)-induced Dissolution of Podosomes Cellular and Molecular Life Sciences : CMLS. Jun, 2012 | Pubmed ID: 22204022 The Chemotherapeutic Drug Oxaliplatin Differentially Affects Blood DC Function Dependent on Environmental Cues Cancer Immunology, Immunotherapy : CII. Jul, 2012 | Pubmed ID: 22193989 Unraveling the Human Dendritic Cell Phagosome Proteome by Organellar Enrichment Ranking Journal of Proteomics. Feb, 2012 | Pubmed ID: 22146474 Interlaboratory Round Robin on Cantilever Calibration for AFM Force Spectroscopy Ultramicroscopy. Dec, 2011 | Pubmed ID: 22094372 Early Identification of Antigen-specific Immune Responses in Vivo by [18F]-labeled 3'-fluoro-3'-deoxy-thymidine ([18F]FLT) PET Imaging Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011 | Pubmed ID: 22025695 Targeted Delivery of TLR Ligands to Human and Mouse Dendritic Cells Strongly Enhances Adjuvanticity Blood. Dec, 2011 | Pubmed ID: 21967977 Cytokine Profiles in Cyst Fluids from Ovarian Tumors Reflect Immunosuppressive State of the Tumor International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Oct, 2011 | Pubmed ID: 21946293 Targeting DC-SIGN Via Its Neck Region Leads to Prolonged Antigen Residence in Early Endosomes, Delayed Lysosomal Degradation, and Cross-presentation Blood. Oct, 2011 | Pubmed ID: 21860028 Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment is Founded Specifically Upon TLR9 Function in Plasmacytoid Dendritic Cells Cancer Research. Oct, 2011 | Pubmed ID: 21788345 Route of Administration Modulates the Induction of Dendritic Cell Vaccine-induced Antigen-specific T Cells in Advanced Melanoma Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2011 | Pubmed ID: 21771874 Platinum-based Drugs Disrupt STAT6-mediated Suppression of Immune Responses Against Cancer in Humans and Mice The Journal of Clinical Investigation. Aug, 2011 | Pubmed ID: 21765211 The Influence of PEG Chain Length and Targeting Moiety on Antibody-mediated Delivery of Nanoparticle Vaccines to Human Dendritic Cells Biomaterials. Oct, 2011 | Pubmed ID: 21724247 Antigen Localization Controls T Cell-mediated Tumor Immunity Journal of Immunology (Baltimore, Md. : 1950). Aug, 2011 | Pubmed ID: 21705625 Infection of Dendritic Cells with Herpes Simplex Virus Type 1 Induces Rapid Degradation of CYTIP, Thereby Modulating Adhesion and Migration Blood. Jul, 2011 | Pubmed ID: 21562043 Cytokine Analysis As a Tool to Understand Tumour-host Interaction in Ovarian Cancer European Journal of Cancer (Oxford, England : 1990). Aug, 2011 | Pubmed ID: 21514148 DEC-205 Mediates Antigen Uptake and Presentation by Both Resting and Activated Human Plasmacytoid Dendritic Cells European Journal of Immunology. Apr, 2011 | Pubmed ID: 21413003 Multimodal Imaging of Nanovaccine Carriers Targeted to Human Dendritic Cells Molecular Pharmaceutics. Apr, 2011 | Pubmed ID: 21381651 Eradicating Cancer Cells: Struggle with a Chameleon Oncotarget. Jan-Feb, 2011 | Pubmed ID: 21378413 Targeted Antigen Delivery and Activation of Dendritic Cells in Vivo: Steps Towards Cost Effective Vaccines Seminars in Immunology. Feb, 2011 | Pubmed ID: 21269839 Prophylactic Vaccines Mimic Synthetic CpG Oligonucleotides in Their Ability to Modulate Immune Responses Molecular Immunology. Mar, 2011 | Pubmed ID: 21257206 IL-4 and IL-13 Alter Plasmacytoid Dendritic Cell Responsiveness to CpG DNA and Herpes Simplex Virus-1 The Journal of Investigative Dermatology. Apr, 2011 | Pubmed ID: 21191414 Wild-type and Modified Gp100 Peptide-pulsed Dendritic Cell Vaccination of Advanced Melanoma Patients Can Lead to Long-term Clinical Responses Independent of the Peptide Used Cancer Immunology, Immunotherapy : CII. Feb, 2011 | Pubmed ID: 21069321 A Novel (19)F Agent for Detection and Quantification of Human Dendritic Cells Using Magnetic Resonance Imaging International Journal of Cancer. Journal International Du Cancer. Jul, 2011 | Pubmed ID: 20839261 The Lymphoid Chemokine CCL21 Triggers LFA-1 Adhesive Properties on Human Dendritic Cells Immunology and Cell Biology. Mar, 2011 | Pubmed ID: 20805842 Immunogenicity of Dendritic Cells Pulsed with CEA Peptide or Transfected with CEA MRNA for Vaccination of Colorectal Cancer Patients Anticancer Research. Dec, 2010 | Pubmed ID: 21187495 DC-ATLAS: a Systems Biology Resource to Dissect Receptor Specific Signal Transduction in Dendritic Cells Immunome Research. 2010 | Pubmed ID: 21092113 Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: a Phase I/II Study in Metastatic Melanoma Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2010 | Pubmed ID: 20736326 Customizable, Multi-functional Fluorocarbon Nanoparticles for Quantitative in Vivo Imaging Using 19F MRI and Optical Imaging Biomaterials. Sep, 2010 | Pubmed ID: 20566214 (19)F MRI for Quantitative in Vivo Cell Tracking Trends in Biotechnology. Jul, 2010 | Pubmed ID: 20427096 Commonly Used Prophylactic Vaccines As an Alternative for Synthetically Produced TLR Ligands to Mature Monocyte-derived Dendritic Cells Blood. Jul, 2010 | Pubmed ID: 20424184 The Tetraspanin CD37 Protects Against Glomerular IgA Deposition and Renal Pathology The American Journal of Pathology. May, 2010 | Pubmed ID: 20348240 Human Plasmacytoid Dendritic Cells Phagocytose, Process, and Present Exogenous Particulate Antigen Journal of Immunology (Baltimore, Md. : 1950). Apr, 2010 | Pubmed ID: 20304825 Molecular Friction As a Tool to Identify Functionalized Alkanethiols Langmuir : the ACS Journal of Surfaces and Colloids. May, 2010 | Pubmed ID: 20225883 Toll-like Receptor Expression and Function in Human Dendritic Cell Subsets: Implications for Dendritic Cell-based Anti-cancer Immunotherapy Cancer Immunology, Immunotherapy : CII. Oct, 2010 | Pubmed ID: 20204387 Dendritic Cell Subsets Digested: RNA Sensing Makes the Difference! Immunity. Feb, 2010 | Pubmed ID: 20189479 Consolidative Dendritic Cell-based Immunotherapy Elicits Cytotoxicity Against Malignant Mesothelioma American Journal of Respiratory and Critical Care Medicine. Jun, 2010 | Pubmed ID: 20167848 Targeted PLGA Nano- but Not Microparticles Specifically Deliver Antigen to Human Dendritic Cells Via DC-SIGN in Vitro Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2010 | Pubmed ID: 20156497 Hematopoietic Stem Cells Are Coordinated by the Molecular Cues of the Endosteal Niche Stem Cells and Development. Aug, 2010 | Pubmed ID: 20148648 Ovarian Cancer Creates a Suppressive Microenvironment to Escape Immune Elimination Gynecologic Oncology. May, 2010 | Pubmed ID: 20144842 Dominant Processes During Human Dendritic Cell Maturation Revealed by Integration of Proteome and Transcriptome at the Pathway Level Journal of Proteome Research. Apr, 2010 | Pubmed ID: 20131907 TLR4-mediated Podosome Loss Discriminates Gram-negative from Gram-positive Bacteria in Their Capacity to Induce Dendritic Cell Migration and Maturation Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010 | Pubmed ID: 20038642 Fungal Pattern-recognition Receptors and Tetraspanins: Partners on Antigen-presenting Cells Trends in Immunology. Mar, 2010 | Pubmed ID: 20036798 Mesenchymal Stem Cells Respond to TNF but Do Not Produce TNF Journal of Leukocyte Biology. Feb, 2010 | Pubmed ID: 19897767 The Role of Tetraspanins in the Pathogenesis of Infectious Diseases Microbes and Infection / Institut Pasteur. Feb, 2010 | Pubmed ID: 19896556 Functional Differences Between Mesenchymal Stem Cell Populations Are Reflected by Their Transcriptome Stem Cells and Development. Apr, 2010 | Pubmed ID: 19788395 Route of Administration of the TLR9 Agonist CpG Critically Determines the Efficacy of Cancer Immunotherapy in Mice PloS One. 2009 | Pubmed ID: 20020049 Cord Blood Mesenchymal Stem Cells Propel Human Dendritic Cells to an Intermediate Maturation State and Boost Interleukin-12 Production by Mature Dendritic Cells Immunology. Dec, 2009 | Pubmed ID: 19930046 Hotspots of GPI-anchored Proteins and Integrin Nanoclusters Function As Nucleation Sites for Cell Adhesion Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19850864 The C-type Lectin DC-SIGN Internalizes Soluble Antigens and HIV-1 Virions Via a Clathrin-dependent Mechanism European Journal of Immunology. Jul, 2009 | Pubmed ID: 19585517 Dynamic Re-organization of Individual Adhesion Nanoclusters in Living Cells by Ligand-patterned Surfaces Small (Weinheim an Der Bergstrasse, Germany). Jun, 2009 | Pubmed ID: 19367602 In Situ Expression of Tumor Antigens by Messenger RNA-electroporated Dendritic Cells in Lymph Nodes of Melanoma Patients Cancer Research. Apr, 2009 | Pubmed ID: 19318559 Limited Amounts of Dendritic Cells Migrate into the T-cell Area of Lymph Nodes but Have High Immune Activating Potential in Melanoma Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2009 | Pubmed ID: 19318472 The Tetraspanin Protein CD37 Regulates IgA Responses and Anti-fungal Immunity PLoS Pathogens. Mar, 2009 | Pubmed ID: 19282981 In Vivo Recruitment of Hematopoietic Cells Using Stromal Cell-derived Factor 1 Alpha-loaded Heparinized Three-dimensional Collagen Scaffolds Tissue Engineering. Part A. Jul, 2009 | Pubmed ID: 19108679 DCIR is Endocytosed into Human Dendritic Cells and Inhibits TLR8-mediated Cytokine Production Journal of Leukocyte Biology. Mar, 2009 | Pubmed ID: 19028959 Polyinosinic Polycytidylic Acid Prevents Efficient Antigen Expression After MRNA Electroporation of Clinical Grade Dendritic Cells Cancer Immunology, Immunotherapy : CII. Jul, 2009 | Pubmed ID: 19018531 Vaccine-specific Local T Cell Reactivity in Immunotherapy-associated Vitiligo in Melanoma Patients Cancer Immunology, Immunotherapy : CII. Jan, 2009 | Pubmed ID: 18392619 Mesenchymal Stromal Cells: Tissue Engineers and Immune Response Modulators Archivum Immunologiae Et Therapiae Experimentalis. Sep-Oct, 2008 | Pubmed ID: 18836860 Activation of Human Plasmacytoid Dendritic Cells by TLR9 Impairs Fc GammaRII-mediated Uptake of Immune Complexes and Presentation by MHC Class II Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18832675 The Alpha-kinases TRPM6 and TRPM7, but Not EEF-2 Kinase, Phosphorylate the Assembly Domain of Myosin IIA, IIB and IIC FEBS Letters. Sep, 2008 | Pubmed ID: 18675813 In Vivo Colocalization of Antigen and CpG [corrected] Within Dendritic Cells is Associated with the Efficacy of Cancer Immunotherapy Cancer Research. Jul, 2008 | Pubmed ID: 18593941 Maximizing Dendritic Cell Migration in Cancer Immunotherapy Expert Opinion on Biological Therapy. Jul, 2008 | Pubmed ID: 18549318 No Advantage of Cell-penetrating Peptides over Receptor-specific Antibodies in Targeting Antigen to Human Dendritic Cells for Cross-presentation Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18490772 Dendritic Cell Interaction with Candida Albicans Critically Depends on N-linked Mannan The Journal of Biological Chemistry. Jul, 2008 | Pubmed ID: 18482990 Selective Cancer-germline Gene Expression in Pediatric Brain Tumors Journal of Neuro-oncology. Jul, 2008 | Pubmed ID: 18398575 TRPM7 Regulates Myosin IIA Filament Stability and Protein Localization by Heavy Chain Phosphorylation Journal of Molecular Biology. May, 2008 | Pubmed ID: 18394644 Human and Murine Model Cell Lines for Dendritic Cell Biology Evaluated Immunology Letters. May, 2008 | Pubmed ID: 18384885 Interaction of Acute Lymphopblastic Leukemia Cells with C-type Lectins DC-SIGN and L-SIGN Experimental Hematology. Jul, 2008 | Pubmed ID: 18375037 Massive Autophosphorylation of the Ser/Thr-rich Domain Controls Protein Kinase Activity of TRPM6 and TRPM7 PloS One. 2008 | Pubmed ID: 18365021 PGE2-mediated Podosome Loss in Dendritic Cells is Dependent on Actomyosin Contraction Downstream of the RhoA-Rho-kinase Axis Journal of Cell Science. Apr, 2008 | Pubmed ID: 18334555 Maturation of Monocyte-derived Dendritic Cells with Toll-like Receptor 3 and 7/8 Ligands Combined with Prostaglandin E2 Results in High Interleukin-12 Production and Cell Migration Cancer Immunology, Immunotherapy : CII. Nov, 2008 | Pubmed ID: 18322684 Monocyte Cell Surface Glycosaminoglycans Positively Modulate IL-4-induced Differentiation Toward Dendritic Cells Journal of Immunology (Baltimore, Md. : 1950). Mar, 2008 | Pubmed ID: 18322173 Targeting DCIR on Human Plasmacytoid Dendritic Cells Results in Antigen Presentation and Inhibits IFN-alpha Production Blood. Apr, 2008 | Pubmed ID: 18258799 Distinct Kinetic and Mechanical Properties Govern ALCAM-mediated Interactions As Shown by Single-molecule Force Spectroscopy Journal of Cell Science. Nov, 2007 | Pubmed ID: 17971418 In Vivo Targeting of DC-SIGN-positive Antigen-presenting Cells in a Nonhuman Primate Model Journal of Immunotherapy (Hagerstown, Md. : 1997). Oct, 2007 | Pubmed ID: 17893563 Dendritic-cell Immunotherapy: from Ex Vivo Loading to in Vivo Targeting Nature Reviews. Immunology. Oct, 2007 | Pubmed ID: 17853902 Nanoscale Organization of the Pathogen Receptor DC-SIGN Mapped by Single-molecule High-resolution Fluorescence Microscopy Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. Jul, 2007 | Pubmed ID: 17577901 Phenotypic and Functional Characterization of Mature Dendritic Cells from Pediatric Cancer Patients Pediatric Blood & Cancer. Dec, 2007 | Pubmed ID: 17486645 Ligand-conjugated Quantum Dots Monitor Antigen Uptake and Processing by Dendritic Cells Nano Letters. Apr, 2007 | Pubmed ID: 17388641 Myosin II and Mechanotransduction: a Balancing Act Trends in Cell Biology. Apr, 2007 | Pubmed ID: 17320396 Dectin-1 Interaction with Tetraspanin CD37 Inhibits IL-6 Production Journal of Immunology (Baltimore, Md. : 1950). Jan, 2007 | Pubmed ID: 17182550 Binding of the Adhesion and Pathogen Receptor DC-SIGN by Monocytes is Regulated by the Density of Lewis X Molecules Molecular Immunology. Mar, 2007 | Pubmed ID: 17175026 Sensitivity of Magnetic Resonance Imaging of Dendritic Cells for in Vivo Tracking of Cellular Cancer Vaccines International Journal of Cancer. Journal International Du Cancer. Mar, 2007 | Pubmed ID: 17163419 Relevance of DC-SIGN in DC-induced T Cell Proliferation Journal of Leukocyte Biology. Mar, 2007 | Pubmed ID: 17135574 Cancer-germline Gene Expression in Pediatric Solid Tumors Using Quantitative Real-time PCR International Journal of Cancer. Journal International Du Cancer. Jan, 2007 | Pubmed ID: 17019710 Targeting Antigens to Dendritic Cells in Vivo Immunobiology. 2006 | Pubmed ID: 16920498 C-type Lectins on Dendritic Cells and Their Interaction with Pathogen-derived and Endogenous Glycoconjugates Current Protein & Peptide Science. Aug, 2006 | Pubmed ID: 16918443 Organization of the Integrin LFA-1 in Nanoclusters Regulates Its Activity Molecular Biology of the Cell. Oct, 2006 | Pubmed ID: 16855029 Synergy Between in Situ Cryoablation and TLR9 Stimulation Results in a Highly Effective in Vivo Dendritic Cell Vaccine Cancer Research. Jul, 2006 | Pubmed ID: 16849578 A Critical Role for Prostaglandin E2 in Podosome Dissolution and Induction of High-speed Migration During Dendritic Cell Maturation Journal of Immunology (Baltimore, Md. : 1950). Aug, 2006 | Pubmed ID: 16849464 Plasmacytoid Dendritic Cells of Melanoma Patients Present Exogenous Proteins to CD4+ T Cells After Fc Gamma RII-mediated Uptake The Journal of Experimental Medicine. Jul, 2006 | Pubmed ID: 16785312 Development of 111In-labeled Tumor-associated Antigen Peptides for Monitoring Dendritic-cell-based Vaccination Nuclear Medicine and Biology. May, 2006 | Pubmed ID: 16720236 TRPM7, a Novel Regulator of Actomyosin Contractility and Cell Adhesion The EMBO Journal. Jan, 2006 | Pubmed ID: 16407977 Long-term Engagement of CD6 and ALCAM is Essential for T-cell Proliferation Induced by Dendritic Cells Blood. Apr, 2006 | Pubmed ID: 16352806 Magnetic Resonance Tracking of Dendritic Cells in Melanoma Patients for Monitoring of Cellular Therapy Nature Biotechnology. Nov, 2005 | Pubmed ID: 16258544 Dendritic Cells: Tools and Targets for Antitumor Vaccination Expert Review of Vaccines. Oct, 2005 | Pubmed ID: 16221071 Immunomonitoring Tumor-specific T Cells in Delayed-type Hypersensitivity Skin Biopsies After Dendritic Cell Vaccination Correlates with Clinical Outcome Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Aug, 2005 | Pubmed ID: 16110035 Levels of Complexity in Pathogen Recognition by C-type Lectins Current Opinion in Immunology. Aug, 2005 | Pubmed ID: 15950451 Elevated CXCL16 Expression by Synovial Macrophages Recruits Memory T Cells into Rheumatoid Joints Arthritis and Rheumatism. May, 2005 | Pubmed ID: 15880344 Effective Induction of Naive and Recall T-cell Responses by Targeting Antigen to Human Dendritic Cells Via a Humanized Anti-DC-SIGN Antibody Blood. Aug, 2005 | Pubmed ID: 15878980 "Sweet Talk": Closing in on C Type Lectin Signaling Immunity. Apr, 2005 | Pubmed ID: 15845444 Migration of Dendritic Cell Based Cancer Vaccines: in Vivo Veritas? Current Opinion in Immunology. Apr, 2005 | Pubmed ID: 15766677 How C-type Lectins Detect Pathogens Cellular Microbiology. Apr, 2005 | Pubmed ID: 15760448 Novel Monoclonal Antibodies Detect Elevated Levels of the Chemokine CCL18/DC-CK1 in Serum and Body Fluids in Pathological Conditions Journal of Leukocyte Biology. May, 2005 | Pubmed ID: 15713699 The Dendritic Cell-derived Protein DC-STAMP is Highly Conserved and Localizes to the Endoplasmic Reticulum Journal of Leukocyte Biology. Mar, 2005 | Pubmed ID: 15601667 Phenotypical and Functional Characterization of Clinical-grade Dendritic Cells Methods in Molecular Medicine. 2005 | Pubmed ID: 15585917 In Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity Cancer Research. Jun, 2004 | Pubmed ID: 15173017 Cytoskeletal Restraints Regulate Homotypic ALCAM-mediated Adhesion Through PKCalpha Independently of Rho-like GTPases Journal of Cell Science. Jun, 2004 | Pubmed ID: 15169840 Differentiating Stem Cells Mask Their Origins Stem Cells (Dayton, Ohio). 2004 | Pubmed ID: 15153601 Dendritic Cell Immunotherapy: Mapping the Way Nature Medicine. May, 2004 | Pubmed ID: 15122249 Microdomains of the C-type Lectin DC-SIGN Are Portals for Virus Entry into Dendritic Cells The Journal of Cell Biology. Jan, 2004 | Pubmed ID: 14709546 Presence and Localization of T-cell Subsets in Relation to Melanocyte Differentiation Antigen Expression and Tumour Regression As Assessed by Immunohistochemistry and Molecular Analysis of Microdissected T Cells The Journal of Pathology. Jan, 2004 | Pubmed ID: 14694523 Maturation of Dendritic Cells is a Prerequisite for Inducing Immune Responses in Advanced Melanoma Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2003 | Pubmed ID: 14613986 Dual Function of C-type Lectin-like Receptors in the Immune System Current Opinion in Cell Biology. Oct, 2003 | Pubmed ID: 14519388 An Automated Multi Well Cell Track System to Study Leukocyte Migration Journal of Immunological Methods. Sep, 2003 | Pubmed ID: 12972190 Ceramic Hydroxyapatite Coating on Titanium Implants Drives Selective Bone Marrow Stromal Cell Adhesion Clinical Oral Implants Research. Oct, 2003 | Pubmed ID: 12969360 Analysis of Dendritic Cell Trafficking Using EGFP-transgenic Mice Immunology Letters. Oct, 2003 | Pubmed ID: 12946860 Different Faces of the Heme-heme Oxygenase System in Inflammation Pharmacological Reviews. Sep, 2003 | Pubmed ID: 12869663 The Heme-heme Oxygenase System: a Molecular Switch in Wound Healing Blood. Jul, 2003 | Pubmed ID: 12649161 The C-type Lectin DC-SIGN (CD209) is an Antigen-uptake Receptor for Candida Albicans on Dendritic Cells European Journal of Immunology. Feb, 2003 | Pubmed ID: 12645952 Peptide Fine Specificity of Anti-glycoprotein 100 CTL is Preserved Following Transfer of Engineered TCR Alpha Beta Genes into Primary Human T Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Feb, 2003 | Pubmed ID: 12574392 Expression of the Dendritic Cell-associated C-type Lectin DC-SIGN by Inflammatory Matrix Metalloproteinase-producing Macrophages in Rheumatoid Arthritis Synovium and Interaction with Intercellular Adhesion Molecule 3-positive T Cells Arthritis and Rheumatism. Feb, 2003 | Pubmed ID: 12571844 Effective Migration of Antigen-pulsed Dendritic Cells to Lymph Nodes in Melanoma Patients is Determined by Their Maturation State Cancer Research. Jan, 2003 | Pubmed ID: 12517769 Phenotypical and Functional Characterization of Clinical Grade Dendritic Cells Journal of Immunotherapy (Hagerstown, Md. : 1997). Sep-Oct, 2002 | Pubmed ID: 12218781 The Small GTPase Rap1 is Required for Mn(2+)- and Antibody-induced LFA-1- and VLA-4-mediated Cell Adhesion The Journal of Biological Chemistry. Aug, 2002 | Pubmed ID: 12171996 Renal Cell Carcinoma-associated Antigen G250 Encodes a Naturally Processed Epitope Presented by Human Leukocyte Antigen-DR Molecules to CD4(+) T Lymphocytes International Journal of Cancer. Journal International Du Cancer. Aug, 2002 | Pubmed ID: 12115527 Enhancement of G-CSF-induced Stem Cell Mobilization by Antibodies Against the Beta 2 Integrins LFA-1 and Mac-1 Blood. Jul, 2002 | Pubmed ID: 12070044 C-type Lectin Receptors on Dendritic Cells and Langerhans Cells Nature Reviews. Immunology. Feb, 2002 | Pubmed ID: 11910898 The Dendritic Cell-specific Adhesion Receptor DC-SIGN Internalizes Antigen for Presentation to T Cells Journal of Immunology (Baltimore, Md. : 1950). Mar, 2002 | Pubmed ID: 11859097 Identification of Different Binding Sites in the Dendritic Cell-specific Receptor DC-SIGN for Intercellular Adhesion Molecule 3 and HIV-1 The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11799126 Regulation of LFA-1 Expression by CD34 Positive Cells and Inducible Growth Factor Production by Stroma Enable Formation of Bone Marrow Compartments; Subject Heading Hematology (Amsterdam, Netherlands). 2000 | Pubmed ID: 11399626 Multiplex Immunohistochemical Analysis of the Spatial Immune Cell Landscape of the Tumor Microenvironment Mark A. J. Gorris1,2, Evgenia Martynova*1,3, Mark W. D. Sweep*1,4, Iris A. E. van der Hoorn1,5, Shabaz Sultan1,3, Mike J. D. E. Claassens1, Lieke L. van der Woude1,2,6, Kiek Verrijp1,2,6, Carl G. Figdor1,3, Johannes Textor1,3, I. Jolanda M. de Vries1 1Department of Medical BioSciences, Radboudumc, 2Division of Immunotherapy, Oncode Institute, Radboudumc, 3Data Science, Institute for Computing and Information Sciences, Radboud University, 4Department of Medical Oncology, Radboudumc, 5Department of Pulmonary Diseases, Radboudumc, 6Department of Pathology, Radboudumc JoVE 65717 Cancer Research In vivo 19F MRI for Cell Tracking Mangala Srinivas1, Philipp Boehm-Sturm2, Markus Aswendt2, Eberhard D. Pracht2,3, Carl G. Figdor1, I. Jolanda de Vries1, Mathias Hoehn2 1Department of Tumor Immunology, Nijmegen Center for Molecular Life Sciences, Radboud University Medical Center, 2In-Vivo-NMR Laboratory, Max Planck Institute for Neurological Research, 3German Center for Neurodegenerative Diseases (DZNE) JoVE 50802 Medicine
Multiplex Immunohistochemical Analysis of the Spatial Immune Cell Landscape of the Tumor Microenvironment Mark A. J. Gorris1,2, Evgenia Martynova*1,3, Mark W. D. Sweep*1,4, Iris A. E. van der Hoorn1,5, Shabaz Sultan1,3, Mike J. D. E. Claassens1, Lieke L. van der Woude1,2,6, Kiek Verrijp1,2,6, Carl G. Figdor1,3, Johannes Textor1,3, I. Jolanda M. de Vries1 1Department of Medical BioSciences, Radboudumc, 2Division of Immunotherapy, Oncode Institute, Radboudumc, 3Data Science, Institute for Computing and Information Sciences, Radboud University, 4Department of Medical Oncology, Radboudumc, 5Department of Pulmonary Diseases, Radboudumc, 6Department of Pathology, Radboudumc JoVE 65717 Cancer Research
In vivo 19F MRI for Cell Tracking Mangala Srinivas1, Philipp Boehm-Sturm2, Markus Aswendt2, Eberhard D. Pracht2,3, Carl G. Figdor1, I. Jolanda de Vries1, Mathias Hoehn2 1Department of Tumor Immunology, Nijmegen Center for Molecular Life Sciences, Radboud University Medical Center, 2In-Vivo-NMR Laboratory, Max Planck Institute for Neurological Research, 3German Center for Neurodegenerative Diseases (DZNE) JoVE 50802 Medicine