Jennifer A. Littlechild Department of Biosciences University of Exeter Biography Publications Institution JoVE Articles Jennifer A. Littlechild has not added a biography. If you are Jennifer A. Littlechild and would like to personalize this page please email our Author Liaison for assistance. Publications The Substrate Specificity, Enantioselectivity and Structure of the (R)-selective Amine : Pyruvate Transaminase from Nectria Haematococca The FEBS Journal. May, 2014 | Pubmed ID: 24618038 Biochemical and Structural Characterisation of a Haloalkane Dehalogenase from a Marine Rhodobacteraceae FEBS Letters. May, 2014 | Pubmed ID: 24613925 Functional and Structural Characterisation of a Viral Cytochrome B5 FEBS Letters. Nov, 2013 | Pubmed ID: 24100138 Characterisation of an L-haloacid Dehalogenase from the Marine Psychrophile Psychromonas Ingrahamii with Potential Industrial Application Marine Biotechnology (New York, N.Y.). Dec, 2013 | Pubmed ID: 23949008 Structural Studies of Pseudomonas and Chromobacterium ω-aminotransferases Provide Insights into Their Differing Substrate Specificity Acta Crystallographica. Section D, Biological Crystallography. Apr, 2013 | Pubmed ID: 23519665 Marine Rhodobacteraceae L-haloacid Dehalogenase Contains a Novel His/Glu Dyad That Could Activate the Catalytic Water The FEBS Journal. Apr, 2013 | Pubmed ID: 23384397 Amino Acid Properties May Be Useful in Predicting Clinical Outcome in Patients with Kir6.2 Neonatal Diabetes European Journal of Endocrinology / European Federation of Endocrine Societies. Sep, 2012 | Pubmed ID: 22648966 Lymphocytes from Rheumatoid Arthritis Patients Have Elevated Levels of Intracellular Peroxiredoxin 2, and a Greater Frequency of Cells with Exofacial Peroxiredoxin 2, Compared with Healthy Human Lymphocytes The International Journal of Biochemistry & Cell Biology. Aug, 2012 | Pubmed ID: 22565169 Thermophilic Archaeal Enzymes and Applications in Biocatalysis Biochemical Society Transactions. Jan, 2011 | Pubmed ID: 21265764 An NADPH-dependent Genetic Switch Regulates Plant Infection by the Rice Blast Fungus Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21115813 Crystal Structure of a Thermostable Old Yellow Enzyme from Thermus Scotoductus SA-01 Biochemical and Biophysical Research Communications. Mar, 2010 | Pubmed ID: 20138824 A Microreactor for the Study of Biotransformations by a Cross-linked Gamma-lactamase Enzyme Biotechnology Journal. Apr, 2009 | Pubmed ID: 19291707 Biochemical and Structural Studies of a L-haloacid Dehalogenase from the Thermophilic Archaeon Sulfolobus Tokodaii Extremophiles : Life Under Extreme Conditions. Jan, 2009 | Pubmed ID: 19039518 The Binding of Haem and Zinc in the 1.9 A X-ray Structure of Escherichia Coli Bacterioferritin Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Feb, 2009 | Pubmed ID: 18946693 The Fasciola Hepatica Thioredoxin: High Resolution Structure Reveals Two Oxidation States Molecular and Biochemical Parasitology. Sep, 2008 | Pubmed ID: 18620002 An Order-disorder Twin Crystal of L-2-haloacid Dehalogenase from Sulfolobus Tokodaii Acta Crystallographica. Section D, Biological Crystallography. Aug, 2007 | Pubmed ID: 17642519 Tps1 Regulates the Pentose Phosphate Pathway, Nitrogen Metabolism and Fungal Virulence The EMBO Journal. Aug, 2007 | Pubmed ID: 17641690 Crystallization and Preliminary X-ray Diffraction Analysis of Omega-amino Acid:pyruvate Transaminase from Chromobacterium Violaceum Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Feb, 2007 | Pubmed ID: 17277454 Arabidopsis Thaliana VTC4 Encodes L-galactose-1-P Phosphatase, a Plant Ascorbic Acid Biosynthetic Enzyme The Journal of Biological Chemistry. Jun, 2006 | Pubmed ID: 16595667 Synthesis and Characterisation of a Ligand That Forms a Stable Tetrahedral Intermediate in the Active Site of the Aureobacterium Species (-) Gamma-lactamase Organic & Biomolecular Chemistry. Sep, 2005 | Pubmed ID: 16132085 Crystallization and Preliminary X-ray Diffraction Studies of a Fungal Hydrolase from Ophiostoma Novo-ulmi Acta Crystallographica. Section D, Biological Crystallography. Oct, 2004 | Pubmed ID: 15388939 The Crystal Structure of a (-) Gamma-lactamase from an Aureobacterium Species Reveals a Tetrahedral Intermediate in the Active Site Journal of Molecular Biology. Apr, 2004 | Pubmed ID: 15081810 Cloning and Expression of Cytosolic Phosphoglycerate Kinase from Pea (Pisum Sativum L.) Journal of Experimental Botany. Apr, 2004 | Pubmed ID: 14990625 Metal and Redox Modulation of Cysteine Protein Function Chemistry & Biology. Aug, 2003 | Pubmed ID: 12954327 The Structure of an Alcohol Dehydrogenase from the Hyperthermophilic Archaeon Aeropyrum Pernix Journal of Molecular Biology. Aug, 2003 | Pubmed ID: 12927540 Crystallization and Preliminary X-ray Diffraction Studies of a Novel Alcohol Dehydrogenase from the Hyperthermophilic Archaeon Aeropyrum Pernix Acta Crystallographica. Section D, Biological Crystallography. Jan, 2003 | Pubmed ID: 12499562 A Thermostable L-aminoacylase from Thermococcus Litoralis: Cloning, Overexpression, Characterization, and Applications in Biotransformations Extremophiles : Life Under Extreme Conditions. Apr, 2002 | Pubmed ID: 12013431 Crystallization and Preliminary X-ray Diffraction Analysis of L-aminoacylase from the Hyperthermophilic Archaeon Thermococcus Litoralis Acta Crystallographica. Section D, Biological Crystallography. Mar, 2002 | Pubmed ID: 11856837 Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry Mirella Vivoli1, Halina R. Novak1, Jennifer A. Littlechild1, Nicholas J. Harmer1 1Department of Biosciences, University of Exeter JoVE 51809 Biology
Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry Mirella Vivoli1, Halina R. Novak1, Jennifer A. Littlechild1, Nicholas J. Harmer1 1Department of Biosciences, University of Exeter JoVE 51809 Biology