Jerome Engel Jr. Department of Neurology University of California, Los Angeles Biography Publications Institution JoVE Articles Jerome Engel Jr. has not added a biography. If you are Jerome Engel Jr. and would like to personalize this page please email our Author Liaison for assistance. Publications Structural and Functional Correlates of Epileptogenesis - Does Gender Matter? Neurobiology of Disease. Jun, 2014 | Pubmed ID: 24943053 Workshop on Neurobiology of Epilepsy Appraisal: New Systemic Imaging Technologies to Study the Brain in Experimental Models of Epilepsy Epilepsia. Jun, 2014 | Pubmed ID: 24836499 Approaches to Refractory Epilepsy Annals of Indian Academy of Neurology. Mar, 2014 | Pubmed ID: 24791078 ILAE Official Report: a Practical Clinical Definition of Epilepsy Epilepsia. Apr, 2014 | Pubmed ID: 24730690 Past and Present Definitions of Epileptogenesis and Its Biomarkers Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Apr, 2014 | Pubmed ID: 24492975 Functional Connectivity in the Brain Estimated by Analysis of Gamma Events PloS One. 2014 | Pubmed ID: 24465774 Functional Connectivity of Hippocampal Networks in Temporal Lobe Epilepsy Epilepsia. Jan, 2014 | Pubmed ID: 24313597 Managing Common Complex Symptomatic Epilepsies: Tumors and Trauma: American Epilepsy Society - 2012 Annual Course Summary Epilepsy Currents / American Epilepsy Society. Sep, 2013 | Pubmed ID: 24348117 Quantitative Analysis of Structural Neuroimaging of Mesial Temporal Lobe Epilepsy Imaging in Medicine. Jun, 2013 | Pubmed ID: 24319498 Single-unit Activities During Epileptic Discharges in the Human Hippocampal Formation Frontiers in Computational Neuroscience. 2013 | Pubmed ID: 24151464 Epilepsy Biomarkers Epilepsia. Aug, 2013 | Pubmed ID: 23909854 Epilepsy, Cognition, and Neuropsychiatry (Epilepsy, Brain, and Mind, Part 2) Epilepsy & Behavior : E&B. Aug, 2013 | Pubmed ID: 23764496 Epilepsy, Behavior, and Art (Epilepsy, Brain, and Mind, Part 1) Epilepsy & Behavior : E&B. Aug, 2013 | Pubmed ID: 23764495 Connectomics and Epilepsy Current Opinion in Neurology. Apr, 2013 | Pubmed ID: 23406911 Progress in the Field of Epilepsy Current Opinion in Neurology. Apr, 2013 | Pubmed ID: 23400236 Functional Connectivity Between Brain Areas Estimated by Analysis of Gamma Waves Journal of Neuroscience Methods. Apr, 2013 | Pubmed ID: 23376499 Effect of Lateralized Temporal Lobe Epilepsy on the Default Mode Network Epilepsy & Behavior : E&B. Nov, 2012 | Pubmed ID: 23103309 Who is a Surgical Candidate? Handbook of Clinical Neurology. 2012 | Pubmed ID: 22939068 Overcoming Barriers to Successful Epilepsy Management Epilepsy Currents / American Epilepsy Society. Jul, 2012 | Pubmed ID: 22936891 Finding a Better Drug for Epilepsy: Preclinical Screening Strategies and Experimental Trial Design Epilepsia. Nov, 2012 | Pubmed ID: 22708847 Early Surgical Therapy for Drug-resistant Temporal Lobe Epilepsy: a Randomized Trial JAMA : the Journal of the American Medical Association. Mar, 2012 | Pubmed ID: 22396514 High-frequency Oscillations - Where We Are and Where We Need to Go Progress in Neurobiology. Sep, 2012 | Pubmed ID: 22342736 Non-linear Classification of Heart Rate Parameters As a Biomarker for Epileptogenesis Epilepsy Research. Jun, 2012 | Pubmed ID: 22305585 Identification of New Epilepsy Treatments: Issues in Preclinical Methodology Epilepsia. Mar, 2012 | Pubmed ID: 22292566 Going Beyond Hippocampocentricity in the Concept of Mesial Temporal Lobe Epilepsy Epilepsia. Jan, 2012 | Pubmed ID: 22221162 Gray Matter Loss Correlates with Mesial Temporal Lobe Neuronal Hyperexcitability Inside the Human Seizure-onset Zone Epilepsia. Jan, 2012 | Pubmed ID: 22126325 Biomarkers in Epilepsy: Introduction Biomarkers in Medicine. Oct, 2011 | Pubmed ID: 22003902 Extending Applications for High-frequency Oscillations: the Ripple Effect Neurology. Aug, 2011 | Pubmed ID: 21753164 A Systems Level, Functional Genomics Analysis of Chronic Epilepsy PloS One. 2011 | Pubmed ID: 21695113 The Etiologic Classification of Epilepsy Epilepsia. Jun, 2011 | Pubmed ID: 21671927 Another Good Reason to Consider Surgical Treatment for Epilepsy More Often and Sooner Archives of Neurology. Jun, 2011 | Pubmed ID: 21670394 Further Evidence That Pathologic High-frequency Oscillations Are Bursts of Population Spikes Derived from Recordings of Identified Cells in Dentate Gyrus Epilepsia. Jan, 2011 | Pubmed ID: 21204820 Do We Belittle Epilepsy by Calling It a Disorder Rather Than a Disease? Epilepsia. Nov, 2010 | Pubmed ID: 21175600 Diverse Perspectives on Developments in Epilepsy Surgery Seizure : the Journal of the British Epilepsy Association. Dec, 2010 | Pubmed ID: 21093313 Referral Pattern for Epilepsy Surgery After Evidence-based Recommendations: a Retrospective Study Neurology. Aug, 2010 | Pubmed ID: 20733145 Definition of the Postictal State: when Does It Start and End? Epilepsy & Behavior : E&B. Oct, 2010 | Pubmed ID: 20692877 Design Considerations for a Multicenter Randomized Controlled Trial of Early Surgery for Mesial Temporal Lobe Epilepsy Epilepsia. Oct, 2010 | Pubmed ID: 20550556 New Approaches to Structural and Functional Imaging in Focal Epilepsy Epilepsia. Feb, 2010 | Pubmed ID: 20331726 High-frequency Oscillations in Epileptic Brain Current Opinion in Neurology. Apr, 2010 | Pubmed ID: 20160649 Epileptogenic Temporal Cavernous Malformations: Operative Strategies and Postoperative Seizure Outcomes Seizure : the Journal of the British Epilepsy Association. Mar, 2010 | Pubmed ID: 20045354 Morpho-physiologic Characteristics of Dorsal Subicular Network in Mice After Pilocarpine-induced Status Epilepticus Brain Pathology (Zurich, Switzerland). Jan, 2010 | Pubmed ID: 19298597 Three-dimensional Surface Maps Link Local Atrophy and Fast Ripples in Human Epileptic Hippocampus Annals of Neurology. Dec, 2009 | Pubmed ID: 20035513 Commentary: Hormones, Diet, and Botanicals Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Apr, 2009 | Pubmed ID: 19332339 The ILAE --where It Was, and Where It is Going: a Personal View Epilepsia. Mar, 2009 | Pubmed ID: 19317879 The Cause of the Imbalance in the Neuronal Network Leading to Seizure Activity Can Be Predicted by the Electrographic Pattern of the Seizure Onset The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2009 | Pubmed ID: 19295168 Assessment and Surgical Outcomes for Mild Type I and Severe Type II Cortical Dysplasia: a Critical Review and the UCLA Experience Epilepsia. Jun, 2009 | Pubmed ID: 19175385 High-frequency Oscillations: What is Normal and What is Not? Epilepsia. Apr, 2009 | Pubmed ID: 19055491 Three-dimensional Hippocampal Atrophy Maps Distinguish Two Common Temporal Lobe Seizure-onset Patterns Epilepsia. Jun, 2009 | Pubmed ID: 19054395 Surgical Treatment for Epilepsy: Too Little, Too Late? JAMA : the Journal of the American Medical Association. Dec, 2008 | Pubmed ID: 19050199 More on the History of Temporal Lobe Surgery Epilepsia. Aug, 2008 | Pubmed ID: 18754947 Cell Type-specific Firing During Ripple Oscillations in the Hippocampal Formation of Humans The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18550752 Functionalized Magnetonanoparticles for MRI Diagnosis and Localization in Epilepsy Epilepsia. Aug, 2008 | Pubmed ID: 18479391 Progress in Epilepsy: Reducing the Treatment Gap and the Promise of Biomarkers Current Opinion in Neurology. Apr, 2008 | Pubmed ID: 18317272 Voltage Depth Profiles of High-frequency Oscillations After Kainic Acid-induced Status Epilepticus Epilepsia. 2007 | Pubmed ID: 17910579 Dealing with Drug Dependency: a Commentary on ILAE's Partnership with the Pharmaceutical Industry Epilepsia. Oct, 2007 | Pubmed ID: 17683507 Increased Fast Ripple to Ripple Ratios Correlate with Reduced Hippocampal Volumes and Neuron Loss in Temporal Lobe Epilepsy Patients Epilepsia. Nov, 2007 | Pubmed ID: 17662059 Analysis of Initial Slow Waves (ISWs) at the Seizure Onset in Patients with Drug Resistant Temporal Lobe Epilepsy Epilepsia. Oct, 2007 | Pubmed ID: 17559569 Proposal of an Algorithm for Diagnosis and Treatment of Neonatal Seizures in Developing Countries Epilepsia. Jun, 2007 | Pubmed ID: 17442012 Reduced Neocortical Thickness and Complexity Mapped in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis Cerebral Cortex (New York, N.Y. : 1991). Sep, 2007 | Pubmed ID: 17088374 Report of the ILAE Classification Core Group Epilepsia. Sep, 2006 | Pubmed ID: 16981873 Hippocampal Atrophy and the Prognosis of Epilepsy: Some Answers, More Questions Neurology. Jul, 2006 | Pubmed ID: 16832070 ILAE Classification of Epilepsy Syndromes Epilepsy Research. Aug, 2006 | Pubmed ID: 16822650 Are Epilepsy Classifications Based on Epileptic Syndromes and Seizure Types Outdated? Epileptic Disorders : International Epilepsy Journal with Videotape. Jun, 2006 | Pubmed ID: 16793579 Extracellular Adenosine in the Human Brain During Sleep and Sleep Deprivation: an in Vivo Microdialysis Study Sleep. Apr, 2006 | Pubmed ID: 16676778 Classification is Not EZ Epileptic Disorders : International Epilepsy Journal with Videotape. Dec, 2005 | Pubmed ID: 17201052 Analysis of Chronic Seizure Onsets After Intrahippocampal Kainic Acid Injection in Freely Moving Rats Epilepsia. Oct, 2005 | Pubmed ID: 16190929 Epilepsy and Seizure Disorder Epilepsia. Aug, 2005 | Pubmed ID: 16060952 Analysis of Seizure Onset on the Basis of Wideband EEG Recordings Epilepsia. 2005 | Pubmed ID: 15987255 Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE) Epilepsia. Apr, 2005 | Pubmed ID: 15816939 Reduced Anesthetization During the Intracarotid Amobarbital (Wada) Test in Patients Taking Carbonic Anhydrase-inhibiting Medications Epilepsia. Feb, 2005 | Pubmed ID: 15679504 Epilepsy Surgery and the Racial Divide Neurology. Jan, 2005 | Pubmed ID: 15642895 Models of Focal Epilepsy Supplements to Clinical Neurophysiology. 2004 | Pubmed ID: 16106638 Seizure Incidence During Single- and Paired-pulse Transcranial Magnetic Stimulation (TMS) in Individuals with Epilepsy Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. Dec, 2004 | Pubmed ID: 15546781 High-frequency Oscillations After Status Epilepticus: Epileptogenesis and Seizure Genesis Epilepsia. Sep, 2004 | Pubmed ID: 15329064 High-frequency Oscillations Recorded in Human Medial Temporal Lobe During Sleep Annals of Neurology. Jul, 2004 | Pubmed ID: 15236407 Unilateral Hippocampal Sclerosis with Contralateral Temporal Scalp Ictal Onset Epilepsia. Jul, 2004 | Pubmed ID: 15230704 The Goal of Epilepsy Therapy: No Seizures, No Side Effects, As Soon As Possible CNS Spectrums. Feb, 2004 | Pubmed ID: 14999165 Large-scale Microarray Gene Expression Analysis in Discrete Electrophysiologically Identified Neuronal Clusters Journal of Neuroscience Methods. Feb, 2004 | Pubmed ID: 14757344 A Greater Role for Surgical Treatment of Epilepsy: Why and When? Epilepsy Currents / American Epilepsy Society. Mar, 2003 | Pubmed ID: 15309078 Advances in Understanding the Process of Epileptogenesis Based on Patient Material: What Can the Patient Tell Us? Epilepsia. 2003 | Pubmed ID: 14641562 Practice Parameter: Temporal Lobe and Localized Neocortical Resections for Epilepsy Epilepsia. Jun, 2003 | Pubmed ID: 12790886 Bringing Epilepsy out of the Shadows Neurology. May, 2003 | Pubmed ID: 12743222 Patient Attitudes About Treatments for Intractable Epilepsy Epilepsy & Behavior : E&B. Feb, 2003 | Pubmed ID: 12609224 Single Neuron Burst Firing in the Human Hippocampus During Sleep Hippocampus. 2002 | Pubmed ID: 12542225 Simultaneous EEG and FMRI of the Alpha Rhythm Neuroreport. Dec, 2002 | Pubmed ID: 12499854 Quantitative Analysis of High-frequency Oscillations (80-500 Hz) Recorded in Human Epileptic Hippocampus and Entorhinal Cortex Journal of Neurophysiology. Oct, 2002 | Pubmed ID: 12364503 Interictal High-frequency Oscillations (80-500 Hz) in the Human Epileptic Brain: Entorhinal Cortex Annals of Neurology. Oct, 2002 | Pubmed ID: 12325068 So What Can We Conclude--do Seizures Damage the Brain? Progress in Brain Research. 2002 | Pubmed ID: 12143369 Rate of Interictal Events and Spontaneous Seizures in Epileptic Rats After Electrical Stimulation of Hippocampus and Its Afferents Epilepsia. 2002 | Pubmed ID: 12121300 Sleep States Differentiate Single Neuron Activity Recorded from Human Epileptic Hippocampus, Entorhinal Cortex, and Subiculum The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2002 | Pubmed ID: 12097521 Early Versus Late Surgery for Intractable Seizures Advances in Experimental Medicine and Biology. 2002 | Pubmed ID: 11998832 Increased Afterdischarge Threshold During Kindling in Epileptic Rats Experimental Brain Research. May, 2002 | Pubmed ID: 11976757 Local Generation of Fast Ripples in Epileptic Brain The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2002 | Pubmed ID: 11880532 Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy Zulfi Haneef1,2, Agatha Lenartowicz3, Hsiang J. Yeh4, Jerome Engel Jr.4, John M. Stern4 1Department of Neurology, Baylor College of Medicine, 2Neurology Care Line, Michael E. DeBakey VA Medical Center, 3Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, 4Department of Neurology, University of California, Los Angeles JoVE 51442 Medicine
Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy Zulfi Haneef1,2, Agatha Lenartowicz3, Hsiang J. Yeh4, Jerome Engel Jr.4, John M. Stern4 1Department of Neurology, Baylor College of Medicine, 2Neurology Care Line, Michael E. DeBakey VA Medical Center, 3Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, 4Department of Neurology, University of California, Los Angeles JoVE 51442 Medicine