Peter Neubauer Chair of Bioprocess Engineering, Department of Biotechnology Technische Universität Berlin Biography Publications Institution JoVE Articles Peter Neubauer has not added a biography. If you are Peter Neubauer and would like to personalize this page please email our Author Liaison for assistance. Publications Fungi As Source for New Bio-based Materials: a Patent Review Fungal Biology and Biotechnology. 2019 | Pubmed ID: 31673396 Bioprocess Development for Lantibiotic Ruminococcin-A Production in and Kinetic Insights Into LanM Enzymes Catalysis Frontiers in Microbiology. 2019 | Pubmed ID: 31572338 Characterization of the Metabolic Response of to Shear Stress in Stirred Tanks and Single-Use 2D Rocking Motion Bioreactors for Clavulanic Acid Production Antibiotics (Basel, Switzerland). Sep, 2019 | Pubmed ID: 31569725 Monitoring of Polyhydroxyalkanoate (PHA) Production During High-Cell-Density Plant Oil Cultivations Using Photon Density Wave Spectroscopy Bioengineering (Basel, Switzerland). Sep, 2019 | Pubmed ID: 31546779 Data of Clavulanic Acid and Clavulanate-imidazole Stability At low Temperatures Data in Brief. Apr, 2019 | Pubmed ID: 31372423 A Model-based Framework for Parallel Scale-down Fed-batch Cultivations in Mini-bioreactors for Accelerated Phenotyping Biotechnology and Bioengineering. Nov, 2019 | Pubmed ID: 31317526 A UV/Vis Spectroscopy-Based Assay for Monitoring of Transformations Between Nucleosides and Nucleobases Methods and Protocols. Jul, 2019 | Pubmed ID: 31311105 Monte Carlo Simulations for the Analysis of Non-linear Parameter Confidence Intervals in Optimal Experimental Design Frontiers in Bioengineering and Biotechnology. 2019 | Pubmed ID: 31179278 Construction and Characterization of Broad-host-range Reporter Plasmid Suitable for On-line Analysis of Bacterial Host Responses Related to Recombinant Protein Production Microbial Cell Factories. May, 2019 | Pubmed ID: 31064376 Reproduction of Large-Scale Bioreactor Conditions on Microfluidic Chips Microorganisms. Apr, 2019 | Pubmed ID: 31010155 Antibacterial and Anticancer Activities of Orphan Biosynthetic Gene Clusters from Atlantis II Red Sea Brine Pool Microbial Cell Factories. Mar, 2019 | Pubmed ID: 30885206 Carboxylic Acid Consumption and Production by Corynebacterium Glutamicum Biotechnology Progress. May, 2019 | Pubmed ID: 30851150 Degradation Kinetics of Clavulanic Acid in Fermentation Broths at Low Temperatures Antibiotics (Basel, Switzerland). Jan, 2019 | Pubmed ID: 30658482 CFD Predicted PH Gradients in Lactic Acid Bacteria Cultivations Biotechnology and Bioengineering. Apr, 2019 | Pubmed ID: 30450609 Electrooptical Determination of Polarizability for On-Line Viability and Vitality Quantification of Cultures Frontiers in Bioengineering and Biotechnology. 2018 | Pubmed ID: 30564571 Accelerated Bioprocess Development of Endopolygalacturonase-Production with Using Multivariate Prediction in a 48 Mini-Bioreactor Automated Platform Bioengineering (Basel, Switzerland). Nov, 2018 | Pubmed ID: 30469407 Rocking Aspergillus: Morphology-controlled Cultivation of Aspergillus Niger in a Wave-mixed Bioreactor for the Production of Secondary Metabolites Microbial Cell Factories. Aug, 2018 | Pubmed ID: 30129427 Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide From the Gut Bacterium E1, in Frontiers in Microbiology. 2018 | Pubmed ID: 30093894 Bioinspired Designs, Molecular Premise and Tools for Evaluating the Ecological Importance of Antimicrobial Peptides Pharmaceuticals (Basel, Switzerland). Jul, 2018 | Pubmed ID: 29996512 Automated Cell Treatment for Competence and Transformation of in a High-Throughput Quasi-Turbidostat Using Microtiter Plates Microorganisms. Jun, 2018 | Pubmed ID: 29941834 Application of Continuous Culture Methods to Recombinant Protein Production in Microorganisms Microorganisms. Jun, 2018 | Pubmed ID: 29933583 An Observational Study of Ballooning in Large Spiders: Nanoscale Multifibers Enable Large Spiders' Soaring Flight PLoS Biology. 06, 2018 | Pubmed ID: 29902191 Comparison of Time-gated Surface-enhanced Raman Spectroscopy (TG-SERS) and Classical SERS Based Monitoring of Escherichia Coli Cultivation Samples Biotechnology Progress. 11, 2018 | Pubmed ID: 29882305 Synthesis of Non-canonical Branched-chain Amino Acids in Escherichia Coli and Approaches to Avoid Their Incorporation into Recombinant Proteins Current Opinion in Biotechnology. 10, 2018 | Pubmed ID: 29870877 Importance of the Cultivation History for the Response of Escherichia Coli to Oscillations in Scale-down Experiments Bioprocess and Biosystems Engineering. Sep, 2018 | Pubmed ID: 29808419 Real-time Monitoring of the Budding Index in Saccharomyces Cerevisiae Batch Cultivations with in Situ Microscopy Microbial Cell Factories. May, 2018 | Pubmed ID: 29764434 How Scalable and Suitable Are Single-use Bioreactors? Current Opinion in Biotechnology. 10, 2018 | Pubmed ID: 29753977 Streptomyces Clavuligerus Shows a Strong Association Between TCA Cycle Intermediate Accumulation and Clavulanic Acid Biosynthesis Applied Microbiology and Biotechnology. May, 2018 | Pubmed ID: 29523936 Bare Laser-synthesized Au-based Nanoparticles As Nondisturbing Surface-enhanced Raman Scattering Probes for Bacteria Identification Journal of Biophotonics. 07, 2018 | Pubmed ID: 29388744 Sterol Synthesis and Cell Size Distribution Under Oscillatory Growth Conditions in Saccharomyces Cerevisiae Scale-down Cultivations Yeast (Chichester, England). 02, 2018 | Pubmed ID: 28940694 Micro-Electromechanical Affinity Sensor for the Monitoring of Glucose in Bioprocess Media International Journal of Molecular Sciences. Jun, 2017 | Pubmed ID: 28594350 Erratum To: Pharmacological and Pharmacokinetic Properties of Lanthipeptides Undergoing Clinical Studies Biotechnology Letters. 04, 2017 | Pubmed ID: 28155176 Pharmacological and Pharmacokinetic Properties of Lanthipeptides Undergoing Clinical Studies Biotechnology Letters. Apr, 2017 | Pubmed ID: 28044226 Life Cycle Assessment of Flexibly Fed Biogas Processes for an Improved Demand-oriented Biogas Supply Bioresource Technology. Nov, 2016 | Pubmed ID: 27522120 The Fed-batch Principle for the Molecular Biology Lab: Controlled Nutrient Diets in Ready-made Media Improve Production of Recombinant Proteins in Escherichia Coli Microbial Cell Factories. Jun, 2016 | Pubmed ID: 27317421 Crystal Structures of Two Monomeric Triosephosphate Isomerase Variants Identified Via a Directed-evolution Protocol Selecting for L-arabinose Isomerase Activity Acta Crystallographica. Section F, Structural Biology Communications. 06, 2016 | Pubmed ID: 27303904 Lanthipeptides: Chemical Synthesis Versus in Vivo Biosynthesis As Tools for Pharmaceutical Production Microbial Cell Factories. Jun, 2016 | Pubmed ID: 27267232 Inversion of the Stereochemical Configuration (3S, 5S)-clavaminic Acid into (3R, 5R)-clavulanic Acid: A Computationally-assisted Approach Based on Experimental Evidence Journal of Theoretical Biology. Apr, 2016 | Pubmed ID: 26835563 An Improved HPLC-DAD Method for Clavulanic Acid Quantification in Fermentation Broths of Streptomyces Clavuligerus Journal of Pharmaceutical and Biomedical Analysis. Feb, 2016 | Pubmed ID: 26760242 Scale-up Bioprocess Development for Production of the Antibiotic Valinomycin in Escherichia Coli Based on Consistent Fed-batch Cultivations Microbial Cell Factories. Jun, 2015 | Pubmed ID: 26063334 Structure-based Directed Evolution of a Monomeric Triosephosphate Isomerase: Toward a Pentose Sugar Isomerase Protein Engineering, Design & Selection : PEDS. Jun, 2015 | Pubmed ID: 25767111 Response of Corynebacterium Glutamicum Exposed to Oscillating Cultivation Conditions in a Two- and a Novel Three-compartment Scale-down Bioreactor Biotechnology and Bioengineering. Jun, 2015 | Pubmed ID: 25728062 Toward Microbioreactor Arrays: A Slow-Responding Oxygen Sensor for Monitoring of Microbial Cultures in Standard 96-Well Plates Journal of Laboratory Automation. Aug, 2015 | Pubmed ID: 25720599 Type II Thioesterase Improves Heterologous Biosynthesis of Valinomycin in Escherichia Coli Journal of Biotechnology. Jan, 2015 | Pubmed ID: 25449019 Robotic Platform for Parallelized Cultivation and Monitoring of Microbial Growth Parameters in Microwell Plates Journal of Laboratory Automation. Dec, 2014 | Pubmed ID: 25208534 Identification and Characterization of RNA Guanine-quadruplex Binding Proteins Nucleic Acids Research. Jun, 2014 | Pubmed ID: 24771345 Escherichia Coli As a Cell Factory for Heterologous Production of Nonribosomal Peptides and Polyketides New Biotechnology. Dec, 2014 | Pubmed ID: 24704144 Quantitative and Sensitive RNA Based Detection of Bacillus Spores Frontiers in Microbiology. 2014 | Pubmed ID: 24653718 Enhanced Production of the Nonribosomal Peptide Antibiotic Valinomycin in Escherichia Coli Through Small-scale High Cell Density Fed-batch Cultivation Applied Microbiology and Biotechnology. Jan, 2014 | Pubmed ID: 24419900 Process Inhomogeneity Leads to Rapid Side Product Turnover in Cultivation of Corynebacterium Glutamicum Microbial Cell Factories. Jan, 2014 | Pubmed ID: 24410842 Reconstituted Biosynthesis of the Nonribosomal Macrolactone Antibiotic Valinomycin in Escherichia Coli ACS Synthetic Biology. Jul, 2014 | Pubmed ID: 24350980 Lactose Autoinduction with Enzymatic Glucose Release: Characterization of the Cultivation System in Bioreactor Protein Expression and Purification. Feb, 2014 | Pubmed ID: 24215862 Cultivation of Marine Microorganisms in Single-use Systems Advances in Biochemical Engineering/biotechnology. 2014 | Pubmed ID: 23893044 Effect of Culture Medium, Host Strain and Oxygen Transfer on Recombinant Fab Antibody Fragment Yield and Leakage to Medium in Shaken E. Coli Cultures Microbial Cell Factories. Jul, 2013 | Pubmed ID: 23895637 Recombinant Protein Production: a Comparative View on Host Physiology (Laupheim, Germany, March 2013) New Biotechnology. Jun, 2013 | Pubmed ID: 23770265 Recombinant Purine Nucleoside Phosphorylases from Thermophiles: Preparation, Properties and Activity Towards Purine and Pyrimidine Nucleosides The FEBS Journal. Mar, 2013 | Pubmed ID: 23332162 Enhanced Plasmid Production in Miniaturized High-cell-density Cultures of Escherichia Coli Supported with Perfluorinated Oxygen Carrier Bioprocess and Biosystems Engineering. Aug, 2013 | Pubmed ID: 23178986 Investigation of Phenolic Acids in Suspension Cultures of Vitis Vinifera Stimulated with Indanoyl-Isoleucine, N-Linolenoyl-L-Glutamine, Malonyl Coenzyme A and Insect Saliva Metabolites. Feb, 2012 | Pubmed ID: 24957372 Glucose-limited High Cell Density Cultivations from Small to Pilot Plant Scale Using an Enzyme-controlled Glucose Delivery System New Biotechnology. Jan, 2012 | Pubmed ID: 22100433 High-yield Production of Biologically Active Recombinant Protein in Shake Flask Culture by Combination of Enzyme-based Glucose Delivery and Increased Oxygen Transfer Microbial Cell Factories. Dec, 2011 | Pubmed ID: 22152005 High-temperature Cultivation and 5' MRNA Optimization Are Key Factors for the Efficient Overexpression of Thermostable Deinococcus Geothermalis Purine Nucleoside Phosphorylase in Escherichia Coli Journal of Biotechnology. Dec, 2011 | Pubmed ID: 21871934 Heterologous Production of Active Ribonuclease Inhibitor in Escherichia Coli by Redox State Control and Chaperonin Coexpression Microbial Cell Factories. Aug, 2011 | Pubmed ID: 21824411 A Two-compartment Bioreactor System Made of Commercial Parts for Bioprocess Scale-down Studies: Impact of Oscillations on Bacillus Subtilis Fed-batch Cultivations Biotechnology Journal. Aug, 2011 | Pubmed ID: 21751400 Two-compartment Method for Determination of the Oxygen Transfer Rate with Electrochemical Sensors Based on Sulfite Oxidation Biotechnology Journal. Aug, 2011 | Pubmed ID: 21751399 Enhanced Growth and Recombinant Protein Production of Escherichia Coli by a Perfluorinated Oxygen Carrier in Miniaturized Fed-batch Cultures Microbial Cell Factories. Jun, 2011 | Pubmed ID: 21708024 Reducing Conditions Are the Key for Efficient Production of Active Ribonuclease Inhibitor in Escherichia Coli Microbial Cell Factories. May, 2011 | Pubmed ID: 21554746 Complete Genome Sequence of the Lytic Pseudomonas Fluorescens Phage ϕIBB-PF7A Virology Journal. Mar, 2011 | Pubmed ID: 21439081 Sandwich ELISA for Quantitative Detection of Human Collagen Prolyl 4-hydroxylase Microbial Cell Factories. Jun, 2010 | Pubmed ID: 20565744 High Cell Density Cultivation and Recombinant Protein Production with Escherichia Coli in a Rocking-motion-type Bioreactor Microbial Cell Factories. 2010 | Pubmed ID: 20509968 Quality Control of Inclusion Bodies in Escherichia Coli Microbial Cell Factories. May, 2010 | Pubmed ID: 20509924 Novel Approach of High Cell Density Recombinant Bioprocess Development: Optimisation and Scale-up from Microliter to Pilot Scales While Maintaining the Fed-batch Cultivation Mode of E. Coli Cultures Microbial Cell Factories. May, 2010 | Pubmed ID: 20487563 Scale-down Simulators for Metabolic Analysis of Large-scale Bioprocesses Current Opinion in Biotechnology. Feb, 2010 | Pubmed ID: 20185293 A Novel Fed-batch Based Cultivation Method Provides High Cell-density and Improves Yield of Soluble Recombinant Proteins in Shaken Cultures Microbial Cell Factories. Feb, 2010 | Pubmed ID: 20167131 Enzyme Controlled Glucose Auto-delivery for High Cell Density Cultivations in Microplates and Shake Flasks Microbial Cell Factories. Nov, 2008 | Pubmed ID: 19017379 Norvaline is Accumulated After a Down-shift of Oxygen in Escherichia Coli W3110 Microbial Cell Factories. Oct, 2008 | Pubmed ID: 18940002 In Situ Microscopy for Real-time Determination of Single-cell Morphology in Bioprocesses Anna Maria Marbà-Ardébol1, Joern Emmerich2, Michael Muthig2, Peter Neubauer1, Stefan Junne1 1Chair of Bioprocess Engineering, Department of Biotechnology, Technische Universität Berlin, 2SOPAT GmbH JoVE 57823 Bioengineering
In Situ Microscopy for Real-time Determination of Single-cell Morphology in Bioprocesses Anna Maria Marbà-Ardébol1, Joern Emmerich2, Michael Muthig2, Peter Neubauer1, Stefan Junne1 1Chair of Bioprocess Engineering, Department of Biotechnology, Technische Universität Berlin, 2SOPAT GmbH JoVE 57823 Bioengineering