Ratha Mahendran Department of Surgery, Yong Loo Lin School of Medicine National University of Singapore, National University Health System Biography Publications Institution JoVE Articles Ratha Mahendran has not added a biography. If you are Ratha Mahendran and would like to personalize this page please email our Author Liaison for assistance. Publications Lactobacillus Rhamnosus GG Activation of Dendritic Cells and Neutrophils Depends on the Dose and Time of Exposure Journal of Immunology Research. 2016 | Pubmed ID: 27525288 Local Immune Stimulation by Intravesical Instillation of Baculovirus to Enable Bladder Cancer Therapy Scientific Reports. Jun, 2016 | Pubmed ID: 27273619 Co-delivery of Peptide-modified Cisplatin and Doxorubicin Via Mucoadhesive Nanocapsules for Potential Synergistic Intravesical Chemotherapy of Non-muscle-invasive Bladder Cancer European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Mar, 2016 | Pubmed ID: 26780592 Mucoadhesive Polyacrylamide Nanogel As a Potential Hydrophobic Drug Carrier for Intravesical Bladder Cancer Therapy European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. May, 2015 | Pubmed ID: 25772330 Metabonomic Profiling of Bladder Cancer Journal of Proteome Research. Feb, 2015 | Pubmed ID: 25388527 Functionalized Mesoporous Silica Nanoparticles with Mucoadhesive and Sustained Drug Release Properties for Potential Bladder Cancer Therapy Langmuir : the ACS Journal of Surfaces and Colloids. Jun, 2014 | Pubmed ID: 24824061 Urinary Metabotyping of Bladder Cancer Using Two-dimensional Gas Chromatography Time-of-flight Mass Spectrometry Journal of Proteome Research. Sep, 2013 | Pubmed ID: 23885889 In Vivo Photodynamic Therapy Using Upconversion Nanoparticles As Remote-controlled Nanotransducers Nature Medicine. Oct, 2012 | Pubmed ID: 22983397 Bacillus Calmette-Guérin Induces Cellular Reactive Oxygen Species and Lipid Peroxidation in Cancer Cells Urology. Jun, 2012 | Pubmed ID: 22446348 Tumor and Microenvironment Modification During Progression of Murine Orthotopic Bladder Cancer Clinical & Developmental Immunology. 2011 | Pubmed ID: 22013484 Lactobacillus Rhamnosus GG Secreting an Antigen and Interleukin-2 Translocates Across the Gastrointestinal Tract and Induces an Antigen Specific Immune Response Microbiology and Immunology. Oct, 2011 | Pubmed ID: 21806675 Lactobacilli Secreting a Tumor Antigen and IL15 Activates Neutrophils and Dendritic Cells and Generates Cytotoxic T Lymphocytes Against Cancer Cells Cellular Immunology. 2011 | Pubmed ID: 21723537 NRAMP1 and HGPX1 Gene Polymorphism and Response to Bacillus Calmette-Guérin Therapy for Bladder Cancer European Urology. Mar, 2011 | Pubmed ID: 21163569 Metabolic Footprinting of Tumorigenic and Nontumorigenic Uroepithelial Cells Using Two-dimensional Gas Chromatography Time-of-flight Mass Spectrometry Analytical and Bioanalytical Chemistry. Oct, 2010 | Pubmed ID: 20686754 Noninvasive Urinary Metabonomic Diagnosis of Human Bladder Cancer Journal of Proteome Research. Jun, 2010 | Pubmed ID: 20337499 Lactobacillus Rhamnosus GG Induces Tumor Regression in Mice Bearing Orthotopic Bladder Tumors Cancer Science. Mar, 2010 | Pubmed ID: 20015287 Live and Lyophilized Lactobacillus Species Elicit Differential Immunomodulatory Effects on Immune Cells FEMS Microbiology Letters. Jan, 2010 | Pubmed ID: 20002187 Mesoporous-silica-coated Up-conversion Fluorescent Nanoparticles for Photodynamic Therapy Small (Weinheim an Der Bergstrasse, Germany). Oct, 2009 | Pubmed ID: 19598161 Tracking Transplanted Cells in Live Animal Using Upconversion Fluorescent Nanoparticles Biomaterials. Oct, 2009 | Pubmed ID: 19539368 Expression of Chemokine/cytokine Genes and Immune Cell Recruitment Following the Instillation of Mycobacterium Bovis, Bacillus Calmette-Guérin or Lactobacillus Rhamnosus Strain GG in the Healthy Murine Bladder Immunology. Jul, 2008 | Pubmed ID: 18217952 Transcriptional Regulation of the COX-2 Expression by Nitric Oxide in Colon Cancer Cell Lines Oncology Reports. Jan, 2008 | Pubmed ID: 18097606 Internalization of Mycobacterium Bovis, Bacillus Calmette Guerin, by Bladder Cancer Cells is Cytotoxic Oncology Reports. Nov, 2007 | Pubmed ID: 17914591 Predictive Value of P53 and PRb Expression in Superficial Bladder Cancer Patients Treated with BCG and Interferon-alpha Cancer. Mar, 2007 | Pubmed ID: 17311305 Combination of Thiol Antioxidant Silibinin with Brostallicin is Associated with Increase in the Anti-apoptotic Protein Bcl-2 and Decrease in Caspase 3 Activity Cancer Letters. Jul, 2006 | Pubmed ID: 16111802 Hypericin-mediated Photodynamic Therapy Elicits Differential Interleukin-6 Response in Nasopharyngeal Cancer Cancer Letters. Apr, 2006 | Pubmed ID: 15935550 Nitrosoglutathione Triggers Collagen Deposition in Cutaneous Wound Repair Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Jul-Aug, 2005 | Pubmed ID: 16008727 Monitoring the Response of Orthotopic Bladder Tumors to Granulocyte Macrophage Colony-stimulating Factor Therapy Using the Prostate-specific Antigen Gene As a Reporter Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2004 | Pubmed ID: 15501977 Non-viral Tumor Necrosis Factor-alpha Gene Transfer Decreases the Incidence of Orthotopic Bladder Tumors International Journal of Molecular Medicine. Oct, 2004 | Pubmed ID: 15375606 Effect of Phospholipase A2 Inhibitory Peptide on Inflammatory Arthritis in a TNF Transgenic Mouse Model: a Time-course Ultrastructural Study Arthritis Research & Therapy. 2004 | Pubmed ID: 15142275 Modulation of Matrix Metalloproteinase-1 in Nasopharyngeal Cancer Cells by Photoactivation of Hypericin International Journal of Oncology. Mar, 2004 | Pubmed ID: 14767550 Nonviral Cytokine Gene Therapy on an Orthotopic Bladder Cancer Model Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2003 | Pubmed ID: 14555526 Nitric Oxide Induces Cyclooxygenase Expression and Inhibits Cell Growth in Colon Cancer Cell Lines Carcinogenesis. Apr, 2003 | Pubmed ID: 12727790 Lactobacillus Species is More Cytotoxic to Human Bladder Cancer Cells Than Mycobacterium Bovis (bacillus Calmette-Guerin) The Journal of Urology. Nov, 2002 | Pubmed ID: 12394766 N-acetylcysteine Augments the Cellular Redox Changes and Cytotoxic Activity of Internalized Mycobacterium Bovis in Human Bladder Cancer Cells The Journal of Urology. Aug, 2002 | Pubmed ID: 12131368 Endogenous Expression of Interleukin-8 and Interleukin-10 in Nasopharyngeal Carcinoma Cells and the Effect of Photodynamic Therapy International Journal of Molecular Medicine. Jul, 2002 | Pubmed ID: 12060853 The Signalling Pathway for BCG-induced Interleukin-6 Production in Human Bladder Cancer Cells Biochemical Pharmacology. Jan, 2002 | Pubmed ID: 11841803 Chemopreventive Effect of Lactobacillus Rhamnosus on Growth of a Subcutaneously Implanted Bladder Cancer Cell Line in the Mouse Japanese Journal of Cancer Research : Gann. Jan, 2002 | Pubmed ID: 11802806 A Murine Orthotopic Bladder Tumor Model and Tumor Detection System Sin Mun Tham1, Kesavan Esuvaranathan1,2, Ratha Mahendran1 1Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, 2Department of Urology, National University Hospital JoVE 55078 Cancer Research
A Murine Orthotopic Bladder Tumor Model and Tumor Detection System Sin Mun Tham1, Kesavan Esuvaranathan1,2, Ratha Mahendran1 1Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, 2Department of Urology, National University Hospital JoVE 55078 Cancer Research