Sebastian Hoffmann seh consulting + services Biography Publications Institution JoVE Articles Sebastian Hoffmann has not added a biography. If you are Sebastian Hoffmann and would like to personalize this page please email our Author Liaison for assistance. Publications Exposure of 19 Substances to Lung A549 Cells at the Air Liquid Interface or Under Submerged Conditions Reveals High Correlation Between Cytotoxicity in Vitro and CLP Classifications for Acute Lung Toxicity Toxicology Letters. Nov, 2019 | Pubmed ID: 31539570 Establishing a Health-based Recommended Occupational Exposure Limit for Nitrous Oxide Using Experimental Animal Data - A Systematic Review Protocol Environmental Research. Nov, 2019 | Pubmed ID: 31520819 The HaCaT/THP-1 Cocultured Activation Test (COCAT) for Skin Sensitization: a Study of Intra-lab Reproducibility and Predictivity ALTEX. 2019 | Pubmed ID: 31132132 Validation of the CULTEX® Radial Flow System for the Assessment of the Acute Inhalation Toxicity of Airborne Particles Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2019 | Pubmed ID: 30890356 Adaptation of the Systematic Review Framework to the Assessment of Toxicological Test Methods: Challenges and Lessons Learned with the Zebrafish Embryotoxicity Test Toxicological Sciences : an Official Journal of the Society of Toxicology. Jun, 2018 | Pubmed ID: 31192353 Validation of the 3D Skin Comet Assay Using Full Thickness Skin Models: Transferability and Reproducibility Mutation Research. Genetic Toxicology and Environmental Mutagenesis. Mar, 2018 | Pubmed ID: 29502735 Non-animal Methods to Predict Skin Sensitization (I): the Cosmetics Europe Database Critical Reviews in Toxicology. 05, 2018 | Pubmed ID: 29474128 Round Robin Study to Evaluate the Reconstructed Human Epidermis (RhE) Model As an in Vitro Skin Irritation Test for Detection of Irritant Activity in Medical Device Extracts Toxicology in Vitro : an International Journal Published in Association with BIBRA. 08, 2018 | Pubmed ID: 29326048 State-of-the-art and New Options to Assess T Cell Activation by Skin Sensitizers: Cosmetics Europe Workshop ALTEX. 2018 | Pubmed ID: 28968481 A Primer on Systematic Reviews in Toxicology Archives of Toxicology. Jul, 2017 | Pubmed ID: 28501917 Evidence-Based Toxicology Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27671725 Catch-up Validation Study of an in Vitro Skin Irritation Test Method Based on an Open Source Reconstructed Epidermis (phase II) Toxicology in Vitro : an International Journal Published in Association with BIBRA. Oct, 2016 | Pubmed ID: 27435616 The Emergence of Systematic Review in Toxicology Toxicological Sciences : an Official Journal of the Society of Toxicology. 07, 2016 | Pubmed ID: 27208075 Guidance on Assessing the Methodological and Reporting Quality of Toxicologically Relevant Studies: A Scoping Review Environment International. Jul-Aug, 2016 | Pubmed ID: 27039952 LLNA Variability: An Essential Ingredient for a Comprehensive Assessment of Non-animal Skin Sensitization Test Methods and Strategies ALTEX. 2015 | Pubmed ID: 26168096 Simple Clotting Test to Detect Procoagulant Abdominal Swabs Journal of Materials Science. Materials in Medicine. Feb, 2015 | Pubmed ID: 25665843 Validation Study on the Ocular Irritection Assay for Eye Irritation Testing Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2014 | Pubmed ID: 24637247 Retrospective Analysis of the Draize Test for Serious Eye Damage/eye Irritation: Importance of Understanding the in Vivo Endpoints Under UN GHS/EU CLP for the Development and Evaluation of in Vitro Test Methods Archives of Toxicology. Mar, 2014 | Pubmed ID: 24374802 Two New Approaches to Improve the Analysis of BALB/c 3T3 Cell Transformation Assay Data Mutation Research. Apr, 2012 | Pubmed ID: 22178130 Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface Amelie Tsoutsoulopoulos1, Katrin Gohlsch2, Niklas Möhle3, Andreas Breit2, Sebastian Hoffmann5, Olaf Krischenowski3,4, Harald Mückter2, Thomas Gudermann2, Horst Thiermann1, Michaela Aufderheide3,4, Dirk Steinritz1,2 1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services JoVE 60572 Medicine
Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface Amelie Tsoutsoulopoulos1, Katrin Gohlsch2, Niklas Möhle3, Andreas Breit2, Sebastian Hoffmann5, Olaf Krischenowski3,4, Harald Mückter2, Thomas Gudermann2, Horst Thiermann1, Michaela Aufderheide3,4, Dirk Steinritz1,2 1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services JoVE 60572 Medicine