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Isolation and Characterization of Bone Marrow Microenvironment in Myeloid Neoplasms

November 10th, 2023
1,2, 1,3, 1,3, 1,2, 1,3,4, 1,5, 1,3
1Wilmot Cancer Institute, University of Rochester Medical Center, 2Department of Biomedical Engineering, University of Rochester, 3Department of Biomedical Genetics, University of Rochester Medical Center, 4Genomics Research Center, University of Rochester Medical Center, 5Division of Endocrinology and Metabolism, Department of Medicine, University of Rochester Medical Center

Summary
Automatic Translation

ここでは、骨髄異形成症候群および急性骨髄性白血病のマウスモデルから骨髄微小環境集団を分離および特徴付けるための詳細なプロトコルが提示されます。この技術は、疾患の進行に伴う内皮細胞や間葉系間質細胞を含む非造血骨髄ニッチの変化を特定します。

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