Alexander J. Szalai Department of Medicine University of Alabama at Birmingham Biography Publications Institution JoVE Articles Alexander J. Szalai has not added a biography. If you are Alexander J. Szalai and would like to personalize this page please email our Author Liaison for assistance. Publications Estrogen Effects on Vascular Inflammation Are Age Dependent: Role of Estrogen Receptors Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2014 | Pubmed ID: 24876352 Associations Between Abnormal Rod-Mediated Dark Adaptation and Health and Functioning in Older Adults with Normal Macular Health Investigative Ophthalmology & Visual Science. May, 2014 | Pubmed ID: 24854857 Inhibiting C-reactive Protein for the Treatment of Cardiovascular Disease: Promising Evidence from Rodent Models Mediators of Inflammation. 2014 | Pubmed ID: 24803739 C-reactive Protein Promotes Acute Kidney Injury by Impairing G1/S-dependent Tubular Epithelium Cell Regeneration Clinical Science (London, England : 1979). May, 2014 | Pubmed ID: 24206243 Multiple Lupus-associated ITGAM Variants Alter Mac-1 Functions on Neutrophils Arthritis and Rheumatism. Nov, 2013 | Pubmed ID: 23918739 C-reactive Protein Exacerbates Renal Ischemia-reperfusion Injury American Journal of Physiology. Renal Physiology. Jun, 2013 | Pubmed ID: 23535585 A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans Molecular Therapy. Nucleic Acids. 2012 | Pubmed ID: 23629027 Pneumococcal Surface Protein A Inhibits Complement Deposition on the Pneumococcal Surface by Competing with the Binding of C-reactive Protein to Cell-surface Phosphocholine Journal of Immunology (Baltimore, Md. : 1950). Dec, 2012 | Pubmed ID: 23105137 Associations of C-Reactive Protein to Indices of Vascular Health and the Influence of Serum 25(OH)D Status in Healthy Adults Journal of Nutrition and Metabolism. 2012 | Pubmed ID: 23029606 Kidney Injury Accelerates Cystogenesis Via Pathways Modulated by Heme Oxygenase and Complement Journal of the American Society of Nephrology : JASN. Jul, 2012 | Pubmed ID: 22518005 Biomarkers of Inflammation and Hemostasis Associated with Left Ventricular Mass: The Multiethnic Study of Atherosclerosis (MESA) International Journal of Molecular Epidemiology and Genetics. 2011 | Pubmed ID: 22200000 An About-face for C-reactive Protein? Clinical Chemistry. Oct, 2011 | Pubmed ID: 21821724 Collagen-induced Arthritis is Exacerbated in C-reactive Protein-deficient Mice Arthritis and Rheumatism. Sep, 2011 | Pubmed ID: 21567377 C - Reaktives Protein Fördert Akute Nieren Entzündung Und Fibrose in Einseitige Ureters Obstruktive Nephropathie Bei Mäusen Laboratory Investigation; a Journal of Technical Methods and Pathology. Jun, 2011 | Pubmed ID: 21383672 Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is FcγRIIB Dependent Autoimmune Diseases. 2011 | Pubmed ID: 21151582 Complement Receptor 1 Expression on Mouse Erythrocytes Mediates Clearance of Streptococcus Pneumoniae by Immune Adherence Infection and Immunity. Jul, 2010 | Pubmed ID: 20439480 C-reactive Protein-mediated Vascular Injury Requires Complement Arteriosclerosis, Thrombosis, and Vascular Biology. Jun, 2010 | Pubmed ID: 20339115 C - Reaktives Protein Fördert Kardialer Fibrose Und Entzündungen Bei Angiotensin II-induzierte Hypertensive Herzkrankheit Hypertension. Apr, 2010 | Pubmed ID: 20157054 The Role of C-reactive Protein Polymorphisms in Inflammation and Cardiovascular Risk Current Atherosclerosis Reports. Mar, 2009 | Pubmed ID: 19228486 Antibody to the Type 3 Capsule Facilitates Immune Adherence of Pneumococci to Erythrocytes and Augments Their Transfer to Macrophages Infection and Immunity. Jan, 2009 | Pubmed ID: 19001076 Immune Opsonins Modulate BLyS/BAFF Release in a Receptor-specific Fashion Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18606652 Impaired Endothelial Function in C-reactive Protein Overexpressing Mice Atherosclerosis. Dec, 2008 | Pubmed ID: 18433756 Neointimal Formation is Reduced After Arterial Injury in Human Crp Transgenic Mice Atherosclerosis. Nov, 2008 | Pubmed ID: 18358478 Exaggerated Neointima Formation in Human C-reactive Protein Transgenic Mice is IgG Fc Receptor Type I (Fc Gamma RI)-dependent The American Journal of Pathology. Jan, 2008 | Pubmed ID: 18063701 PspA and PspC Minimize Immune Adherence and Transfer of Pneumococci from Erythrocytes to Macrophages Through Their Effects on Complement Activation Infection and Immunity. Dec, 2007 | Pubmed ID: 17923519 C-reactive Protein Gene Polymorphisms, C-reactive Protein Blood Levels, and Cardiovascular Disease Risk Journal of the American College of Cardiology. Sep, 2007 | Pubmed ID: 17868801 Complement in Experimental Autoimmune Encephalomyelitis Revisited: C3 is Required for Development of Maximal Disease Molecular Immunology. May, 2007 | Pubmed ID: 17353050 Induction of Leptin Resistance Through Direct Interaction of C-reactive Protein with Leptin Nature Medicine. Apr, 2006 | Pubmed ID: 16582918 Experimental Autoimmune Uveitis in the C57BL/6 Mouse Experimental Eye Research. Jul, 2006 | Pubmed ID: 16524572 Complement and Demyelinating Disease: No MAC Needed? Brain Research Reviews. Aug, 2006 | Pubmed ID: 16443278 Complement in BuB/BnJ Mice Revisited: Serum C3 Levels and Complement Opsonic Activity Are Not Elevated Molecular Immunology. Apr, 2006 | Pubmed ID: 16310250 Genetic Deficiency of C3 As Well As CNS-targeted Expression of the Complement Inhibitor SCrry Ameliorates Experimental Autoimmune Uveoretinitis Experimental Eye Research. Mar, 2006 | Pubmed ID: 16143328 Requirement of the Fc Receptor Common Gamma-chain for Gamma Delta T Cell-mediated Promotion of Murine Experimental Autoimmune Encephalomyelitis European Journal of Immunology. Dec, 2005 | Pubmed ID: 16278814 Complement As a Biomarker in Multiple Sclerosis Journal of Neuropathology and Experimental Neurology. Aug, 2005 | Pubmed ID: 16106223 C3a Expressed in the Central Nervous System Protects Against LPS-induced Shock Neuroscience Letters. Oct, 2005 | Pubmed ID: 16085360 Estrogen Treatment Abrogates Neointima Formation in Human C-reactive Protein Transgenic Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2005 | Pubmed ID: 16051879 Effect of Low Dose Atorvastatin Versus Diet-induced Cholesterol Lowering on Atherosclerotic Lesion Progression and Inflammation in Apolipoprotein E*3-Leiden Transgenic Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2005 | Pubmed ID: 15514207 Murine Complement C4 is Not Required for Experimental Autoimmune Encephalomyelitis Glia. Jan, 2005 | Pubmed ID: 15390104 The Virulence Function of Streptococcus Pneumoniae Surface Protein A Involves Inhibition of Complement Activation and Impairment of Complement Receptor-mediated Protection Journal of Immunology (Baltimore, Md. : 1950). Dec, 2004 | Pubmed ID: 15585877 C-reactive Protein (CRP) and Autoimmune Disease: Facts and Conjectures Clinical & Developmental Immunology. Sep-Dec, 2004 | Pubmed ID: 15559367 Fc Receptors and the Common Gamma-chain in Experimental Autoimmune Encephalomyelitis Journal of Neuroscience Research. Mar, 2004 | Pubmed ID: 14991835 Evidence for Anti-inflammatory Activity of Statins and PPARalpha Activators in Human C-reactive Protein Transgenic Mice in Vivo and in Cultured Human Hepatocytes in Vitro Blood. Jun, 2004 | Pubmed ID: 14976045 C - Reaktives Protein Beschleunigt Das Fortschreiten Der Atherosklerose Apolipoprotein E-defizienten Mäusen Circulation. Feb, 2004 | Pubmed ID: 14744975 Effects of PspA and Antibodies to PspA on Activation and Deposition of Complement on the Pneumococcal Surface Infection and Immunity. Jan, 2004 | Pubmed ID: 14688088 Increased Thrombosis After Arterial Injury in Human C-reactive Protein-transgenic Mice Circulation. Aug, 2003 | Pubmed ID: 12874178 Fc-gamma-Rs Modulieren Zytotoxizität Von Anti-Fas-Antikörper: Implikationen Für Die Agonistische Antikörper-basierter Therapeutika Journal of Immunology (Baltimore, Md. : 1950). Jul, 2003 | Pubmed ID: 12847219 Delayed Lupus Onset in (NZB X NZW)F1 Mice Expressing a Human C-reactive Protein Transgene Arthritis and Rheumatism. Jun, 2003 | Pubmed ID: 12794828 Both Family 1 and Family 2 PspA Proteins Can Inhibit Complement Deposition and Confer Virulence to a Capsular Serotype 3 Strain of Streptococcus Pneumoniae Infection and Immunity. Jan, 2003 | Pubmed ID: 12496151 The Biological Functions of C-reactive Protein Vascular Pharmacology. Aug, 2002 | Pubmed ID: 12616974 Varied Biologic Functions of C-reactive Protein: Lessons Learned from Transgenic Mice Immunologic Research. 2002 | Pubmed ID: 12403365 Experimental Allergic Encephalomyelitis is Inhibited in Transgenic Mice Expressing Human C-reactive Protein Journal of Immunology (Baltimore, Md. : 1950). Jun, 2002 | Pubmed ID: 12023381 The Antimicrobial Activity of C-reactive Protein Microbes and Infection / Institut Pasteur. Feb, 2002 | Pubmed ID: 11880053 Humanen neutrophilen Flusskammer Adhesion Assay Yebin Zhou1, Dennis F. Kucik2,3,4, Alexander J. Szalai5, Jeffrey C. Edberg5 1Genetics and Genomic Sciences Graduate Program, University of Alabama at Birmingham, 2Birmingham Veterans Affairs Medical Center, 3Department of Pathology, University of Alabama at Birmingham, 4Department of Biomedical Engineering, University of Alabama at Birmingham, 5Department of Medicine, University of Alabama at Birmingham JoVE 51410 Immunology and Infection
Humanen neutrophilen Flusskammer Adhesion Assay Yebin Zhou1, Dennis F. Kucik2,3,4, Alexander J. Szalai5, Jeffrey C. Edberg5 1Genetics and Genomic Sciences Graduate Program, University of Alabama at Birmingham, 2Birmingham Veterans Affairs Medical Center, 3Department of Pathology, University of Alabama at Birmingham, 4Department of Biomedical Engineering, University of Alabama at Birmingham, 5Department of Medicine, University of Alabama at Birmingham JoVE 51410 Immunology and Infection