Anna M. Grabowska Division of Cancer & Stem Cells, School of Medicine, Nottingham Biodiscovery Institute University of Nottingham Biography Publications Institution JoVE Articles Anna M. Grabowska has not added a biography. If you are Anna M. Grabowska and would like to personalize this page please email our Author Liaison for assistance. Publications Synthesis of Passerini-3CR Polymers and Assembly into Cytocompatible Polymersomes Macromolecular Rapid Communications. Aug, 2020 | Pubmed ID: 33249682 AKT Isoforms Have Discrete Expression in Triple Negative Breast Cancers and Roles in Cisplatin Sensitivity Oncotarget. Nov, 2020 | Pubmed ID: 33227065 3D Hydrogels Reveal Medulloblastoma Subgroup Differences and Identify Extracellular Matrix Subtypes That Predict Patient Outcome The Journal of Pathology. Nov, 2020 | Pubmed ID: 33206391 Effects of Polymer 3D Architecture, Size, and Chemistry on Biological Transport and Drug Delivery In Vitro and in Orthotopic Triple Negative Breast Cancer Models Advanced Healthcare Materials. Nov, 2020 | Pubmed ID: 33073536 Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells Cancer Research and Treatment : Official Journal of Korean Cancer Association. Oct, 2020 | Pubmed ID: 33070556 A 3D Heterotypic Breast Cancer Model Demonstrates a Role for Mesenchymal Stem Cells in Driving a Proliferative and Invasive Phenotype Cancers. Aug, 2020 | Pubmed ID: 32824003 Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity Mouse Model Journal of Medicinal Chemistry. 07, 2020 | Pubmed ID: 32433887 Synthesis of Micellar-like Terpolymer Nanoparticles with Reductively-cleavable Cross-links and Evaluation of Efficacy in 2D and 3D Models of Triple Negative Breast Cancer Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2020 | Pubmed ID: 32371266 Sonic Hedgehog Ligand: A Role in Formation of a Mesenchymal Niche in Human Pancreatic Ductal Adenocarcinoma Cells. 05, 2019 | Pubmed ID: 31072042 Cancer Reversion with Oocyte Extracts is Mediated by Cell Cycle Arrest and Induction of Tumour Dormancy Oncotarget. Mar, 2018 | Pubmed ID: 29662623 Water-soluble Substituted Chitosan Derivatives As Technology Platform for Inhalation Delivery of SiRNA Drug Delivery. Nov, 2018 | Pubmed ID: 29493294 A HIF-independent, CD133-mediated Mechanism of Cisplatin Resistance in Glioblastoma Cells Cellular Oncology (Dordrecht). Jun, 2018 | Pubmed ID: 29492900 Multicomponent Analysis of the Tumour Microenvironment Reveals Low CD8 T Cell Number, Low Stromal Caveolin-1 and High Tenascin-C and Their Combination As Significant Prognostic Markers in Non-small Cell Lung Cancer Oncotarget. Jan, 2018 | Pubmed ID: 29416729 High-Throughput Spheroid Screens Using Volume, Resazurin Reduction, and Acid Phosphatase Activity Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28470516 Spheroid Arrays for High-throughput Single-cell Analysis of Spatial Patterns and Biomarker Expression in 3D Scientific Reports. 01, 2017 | Pubmed ID: 28134245 Individual Patient Oesophageal Cancer 3D Models for Tailored Treatment Oncotarget. Apr, 2017 | Pubmed ID: 27736801 Separating Chemotherapy-related Developmental Neurotoxicity from Cytotoxicity in Monolayer and Neurosphere Cultures of Human Fetal Brain Cells Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2016 | Pubmed ID: 27622579 In Vitro Models of Medulloblastoma: Choosing the Right Tool for the Job Journal of Biotechnology. Oct, 2016 | Pubmed ID: 27498314 3-Dimensional Patient-Derived Lung Cancer Assays Reveal Resistance to Standards-of-Care Promoted by Stromal Cells but Sensitivity to Histone Deacetylase Inhibitors Molecular Cancer Therapeutics. 04, 2016 | Pubmed ID: 26873730 Systemic in Vivo Delivery of SiRNA to Tumours Using Combination of Polyethyleneimine and Transferrin-polyethyleneimine Conjugates Biomaterials Science. Nov, 2015 | Pubmed ID: 26351701 Multicomponent Synthetic Polymers with Viral-mimetic Chemistry for Nucleic Acid Delivery Molecular Pharmaceutics. Jan, 2012 | Pubmed ID: 22142438 Helicobacter Pylori Potentiates Epithelial:mesenchymal Transition in Gastric Cancer: Links to Soluble HB-EGF, Gastrin and Matrix Metalloproteinase-7 Gut. Aug, 2010 | Pubmed ID: 20584780 A Gastrin Transcript Expressed in Gastrointestinal Cancer Cells Contains an Internal Ribosome Entry Site British Journal of Cancer. May, 2008 | Pubmed ID: 18392051 Cyclopamine Inhibition of the Sonic Hedgehog Pathway in the Stomach Requires Concomitant Acid Inhibition Regulatory Peptides. Feb, 2008 | Pubmed ID: 17996964 Role of Gastrin Peptides in Carcinogenesis Cancer Letters. Nov, 2007 | Pubmed ID: 17698287 Use of Interfering RNA to Investigate the Role of Endogenous Gastrin in the Survival of Gastrointestinal Cancer Cells British Journal of Cancer. Feb, 2007 | Pubmed ID: 17262081 Synthesis and Preliminary Anticancer Activity Studies of C4 and C8-modified Derivatives of Catechin Gallate (CG) and Epicatechin Gallate (ECG) The Journal of Organic Chemistry. Dec, 2006 | Pubmed ID: 17168588 Gastrin - Active Participant or Bystander in Gastric Carcinogenesis? Nature Reviews. Cancer. Dec, 2006 | Pubmed ID: 17128210 Tagged Polymerase Chain Reaction Subtractive Hybridization for the Enrichment of Phage Display Random Peptide Libraries Analytical Biochemistry. Apr, 2005 | Pubmed ID: 15766711 The Biological and Therapeutic Importance of Gastrin Gene Expression in Pancreatic Adenocarcinomas Cancer Research. Aug, 2004 | Pubmed ID: 15313900 Evolutionary Trends of the First Hypervariable Region of the Hepatitis C Virus E2 Protein in Individuals with Differing Liver Disease Severity The Journal of General Virology. Jan, 2002 | Pubmed ID: 11752696 Direct Ex Vivo Comparison of the Breadth and Specificity of the T Cells in the Liver and Peripheral Blood of Patients with Chronic HCV Infection European Journal of Immunology. Aug, 2001 | Pubmed ID: 11500822 Immunisation with Phage Displaying Peptides Representing Single Epitopes of the Glycoprotein G Can Give Rise to Partial Protective Immunity to HSV-2 Virology. Mar, 2000 | Pubmed ID: 10725197 Preparation of a User-Defined Peptide Gel for Controlled 3D Culture Models of Cancer and Disease Jennifer C. Ashworth1, Rebecca L. Morgan1, Kataryna Lis-Slimak1, Kate A. Meade1, Sal Jones1, Katherine Spence2, Charlotte E. Slater1, Jamie L. Thompson1, Anna M. Grabowska1, Robert B. Clarke2, Gilian Farnie3, Cathy L. R. Merry1 1Division of Cancer & Stem Cells, School of Medicine, Nottingham Biodiscovery Institute, University of Nottingham, 2Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 3SGC, Botnar Research Centre, NDORMS, University of Oxford JoVE 61710 Biology
Preparation of a User-Defined Peptide Gel for Controlled 3D Culture Models of Cancer and Disease Jennifer C. Ashworth1, Rebecca L. Morgan1, Kataryna Lis-Slimak1, Kate A. Meade1, Sal Jones1, Katherine Spence2, Charlotte E. Slater1, Jamie L. Thompson1, Anna M. Grabowska1, Robert B. Clarke2, Gilian Farnie3, Cathy L. R. Merry1 1Division of Cancer & Stem Cells, School of Medicine, Nottingham Biodiscovery Institute, University of Nottingham, 2Breast Biology Group, Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, 3SGC, Botnar Research Centre, NDORMS, University of Oxford JoVE 61710 Biology