Catherine Bowes Rickman

Publications

• Distinct Phenotypic Consequences of Pathogenic Mutants Associated with Late-Onset Retinal Degeneration
  The American Journal of Pathology. Oct, 2022   |   Pubmed ID: 36328299
• Cell Culture Models to Study Retinal Pigment Epithelium-related Pathogenesis in Age-related Macular Degeneration
  Experimental Eye Research. Sep, 2022   |   Pubmed ID: 35835183
• Encapsulating Cas9 into Extracellular Vesicles by Protein Myristoylation
  Journal of Extracellular Vesicles. Apr, 2022   |   Pubmed ID: 35384352
• Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models
  Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Month, 2022   |   Pubmed ID: 34788573
• High-density Lipoproteins Are a Potential Therapeutic Target for Age-related Macular Degeneration
  The Journal of Biological Chemistry. Sep, 2020   |   Pubmed ID: 32737203
• Correction To: Retinal Degenerative Diseases
  Advances in Experimental Medicine and Biology. Month, 2019   |   Pubmed ID: 32274704
• Isolation of Retinal Exosome Biomarkers from Blood By Targeted Immunocapture
  Advances in Experimental Medicine and Biology. Month, 2019   |   Pubmed ID: 31884583
• Four-Dimensional Microscope-Integrated Optical Coherence Tomography Guidance in a Model Eye Subretinal Surgery
  Retina (Philadelphia, Pa.). Oct, 2019   |   Pubmed ID: 31090685
• Microglial Function Is Distinct in Different Anatomical Locations During Retinal Homeostasis and Degeneration
  Immunity. Mar, 2019   |   Pubmed ID: 30850344
• Human Complement Factor H Y402H Polymorphism Causes an Age-related Macular Degeneration Phenotype and Lipoprotein Dysregulation in Mice
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2019   |   Pubmed ID: 30808757
• Author Correction: Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers
  Scientific Reports. Nov, 2018   |   Pubmed ID: 30455433
• Polarized Exosome Release from the Retinal Pigmented Epithelium
  Advances in Experimental Medicine and Biology. Month, 2018   |   Pubmed ID: 29721985
• Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration
  Investigative Ophthalmology & Visual Science. Feb, 2018   |   Pubmed ID: 29392311
• Complement Factor H in AMD: Bridging Genetic Associations and Pathobiology
  Progress in Retinal and Eye Research. Jan, 2018   |   Pubmed ID: 28928087
• Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers
  Scientific Reports. Jul, 2017   |   Pubmed ID: 28687758
• Roles of Exosomes in the Normal and Diseased Eye
  Progress in Retinal and Eye Research. Jul, 2017   |   Pubmed ID: 28465248
• Oxidative Stress-mediated NFκB Phosphorylation Upregulates P62/SQSTM1 and Promotes Retinal Pigmented Epithelial Cell Survival Through Increased Autophagy
  PloS One. Month, 2017   |   Pubmed ID: 28222108
• Lack of the P2X Receptor Protects Against AMD-like Defects and Microparticle Accumulation in a Chronic Oxidative Stress-induced Mouse Model of AMD
  Biochemical and Biophysical Research Communications. Jan, 2017   |   Pubmed ID: 27810364
• AMD and the Alternative Complement Pathway: Genetics and Functional Implications
  Human Genomics. Jun, 2016   |   Pubmed ID: 27329102
• A Non-Canonical Role for β-Secretase in the Retina
  Advances in Experimental Medicine and Biology. Month, 2016   |   Pubmed ID: 26427429
• Regulation of Age-related Macular Degeneration-like Pathology by Complement Factor H
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2015   |   Pubmed ID: 25991857
• Expression of Human Complement Factor H Prevents Age-related Macular Degeneration-like Retina Damage and Kidney Abnormalities in Aged Cfh Knockout Mice
  The American Journal of Pathology. Jan, 2015   |   Pubmed ID: 25447048
• Dysregulated Autophagy in the RPE is Associated with Increased Susceptibility to Oxidative Stress and AMD
  Autophagy. Month, 2014   |   Pubmed ID: 25484094
• The Role of Complement Dysregulation in AMD Mouse Models
  Advances in Experimental Medicine and Biology. Month, 2014   |   Pubmed ID: 24664701
• Dry Age-related Macular Degeneration: Mechanisms, Therapeutic Targets, and Imaging
  Investigative Ophthalmology & Visual Science. Dec, 2013   |   Pubmed ID: 24335072
• β-Secretase (BACE1) Inhibition Causes Retinal Pathology by Vascular Dysregulation and Accumulation of Age Pigment
  EMBO Molecular Medicine. Sep, 2012   |   Pubmed ID: 22903875
• Automatic Segmentation of Closed-contour Features in Ophthalmic Images Using Graph Theory and Dynamic Programming
  Biomedical Optics Express. May, 2012   |   Pubmed ID: 22567602
• ApoER2 Function in the Establishment and Maintenance of Retinal Synaptic Connectivity
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2011   |   Pubmed ID: 21976526
• Anti-amyloid Therapy Protects Against Retinal Pigmented Epithelium Damage and Vision Loss in a Model of Age-related Macular Degeneration
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011   |   Pubmed ID: 21690377
• Serial Analysis of Gene Expression (SAGE) in Normal Human Trabecular Meshwork
  Molecular Vision. Apr, 2011   |   Pubmed ID: 21528004
• Heparan Sulfate, Including That in Bruch's Membrane, Inhibits the Complement Alternative Pathway: Implications for Age-related Macular Degeneration
  Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010   |   Pubmed ID: 20876352
• The Pivotal Role of the Complement System in Aging and Age-related Macular Degeneration: Hypothesis Re-visited
  Progress in Retinal and Eye Research. Mar, 2010   |   Pubmed ID: 19961953
• Developing SDOCT to Assess Donor Human Eyes Prior to Tissue Sectioning for Research
  Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Aug, 2009   |   Pubmed ID: 19225801
• Evaluation of the X-linked High-grade Myopia Locus (MYP1) with Cone Dysfunction and Color Vision Deficiencies
  Investigative Ophthalmology & Visual Science. Apr, 2009   |   Pubmed ID: 19098318
• Rapid and Sensitive Method for Detection of Y402, H402, I62, and V62 Variants of Complement Factor H in Human Plasma Samples Using Mass Spectrometry
  Investigative Ophthalmology & Visual Science. Apr, 2009   |   Pubmed ID: 19029036
• NEIBank: Genomics and Bioinformatics Resources for Vision Research
  Molecular Vision. Jul, 2008   |   Pubmed ID: 18648525
• Recurrent Choroidal Neovascularization After Macular Translocation Surgery with 360-degree Peripheral Retinectomy
  Retina (Philadelphia, Pa.). Oct, 2008   |   Pubmed ID: 18626416
• ERG Responses and Microarray Analysis of Gene Expression in a Multifactorial Murine Model of Age-related Retinal Degeneration
  Advances in Experimental Medicine and Biology. Month, 2008   |   Pubmed ID: 18188941
• Targeting Age-related Macular Degeneration with Alzheimer's Disease Based Immunotherapies: Anti-amyloid-beta Antibody Attenuates Pathologies in an Age-related Macular Degeneration Mouse Model
  Vision Research. Feb, 2008   |   Pubmed ID: 17888483
• Oxidative Stress-induced Expression and Modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in Mammalian Retina
  Biochimica Et Biophysica Acta. Sep, 2007   |   Pubmed ID: 17673310
• Initial Observations of Key Features of Age-related Macular Degeneration in APOE Targeted Replacement Mice
  Advances in Experimental Medicine and Biology. Month, 2006   |   Pubmed ID: 17249563
• Why Do Mutations in the Ubiquitously Expressed Housekeeping Gene IMPDH1 Cause Retina-specific Photoreceptor Degeneration?
  Investigative Ophthalmology & Visual Science. Sep, 2006   |   Pubmed ID: 16936083
• Defining the Human Macula Transcriptome and Candidate Retinal Disease Genes Using EyeSAGE
  Investigative Ophthalmology & Visual Science. Jun, 2006   |   Pubmed ID: 16723438
• Recurrence of Retinal Pigment Epithelial Changes After Macular Translocation with 360 Degrees Peripheral Retinectomy for Geographic Atrophy
  Archives of Ophthalmology (Chicago, Ill. : 1960). Jul, 2005   |   Pubmed ID: 16009834
• Human RPE Expression of Cell Survival Factors
  Investigative Ophthalmology & Visual Science. May, 2005   |   Pubmed ID: 15851579
• Unraveling a Multifactorial Late-onset Disease: from Genetic Susceptibility to Disease Mechanisms for Age-related Macular Degeneration
  Annual Review of Genomics and Human Genetics. Month,   |   Pubmed ID: 19405847