David A. Copland

Academic Unit of Ophthalmology, University of Bristol

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2021

Other Publications

Article	Year
Mapping immune responses to mRBP-3 1-16 peptide with altered peptide ligands. Investigative ophthalmology & visual science\| PubMed ID: 16639012	2006
Monoclonal antibody-mediated CD200 receptor signaling suppresses macrophage activation and tissue damage in experimental autoimmune uveoretinitis. The American journal of pathology\| PubMed ID: 17600119	2007
The B subunit of Escherichia coli heat-labile enterotoxin inhibits Th1 but not Th17 cell responses in established experimental autoimmune uveoretinitis. Investigative ophthalmology & visual science\| PubMed ID: 18469197	2008
The dynamics of leukocyte infiltration in experimental autoimmune uveoretinitis. Progress in retinal and eye research\| PubMed ID: 18723108	2008
Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations. Journal of autoimmunity\| PubMed ID: 18838247	2008
TNFR1-dependent regulation of myeloid cell function in experimental autoimmune uveoretinitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19635911	2009
TNFR1 signalling is a critical checkpoint for developing macrophages that control of T-cell proliferation. Immunology\| PubMed ID: 20518824	2010
Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier. The American journal of pathology\| PubMed ID: 22119714	2012
Environmental conditioning in the control of macrophage thrombospondin-1 production. Scientific reports\| PubMed ID: 22803005	2012
Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice. PloS one\| PubMed ID: 23977372	2013
CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization. Scientific reports\| PubMed ID: 24170042	2013
Tissue-Resident Exhausted Effector Memory CD8+ T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24740509	2014
Local targeting of the CD200-CD200R axis does not promote corneal graft survival. Experimental eye research\| PubMed ID: 25450061	2015
Activated adult microglia influence retinal progenitor cell proliferation and differentiation toward recoverin-expressing neuron-like cells in a co-culture model. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 25680876	2015
TNFα Regulates SIRT1 Cleavage during Ocular Autoimmune Disease. The American journal of pathology\| PubMed ID: 25770475	2015
Glucocorticoid-resistant Th17 cells are selectively attenuated by cyclosporine A. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25775512	2015
Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease. Nature medicine\| PubMed ID: 25894827	2015
IL-4 regulates specific Arg-1(+) macrophage sFlt-1-mediated inhibition of angiogenesis. The American journal of pathology\| PubMed ID: 26079814	2015
A novel pathogenic RBP-3 peptide reveals epitope spreading in persistent experimental autoimmune uveoretinitis. Immunology\| PubMed ID: 26152845	2015
Role of interleukin 33/ST2 axis in the immune-mediated pathogenesis of age-related macular degeneration. Lancet (London, England)\| PubMed ID: 26312920	2015
A simple method for in vivo labelling of infiltrating leukocytes in the mouse retina using indocyanine green dye. Disease models & mechanisms\| PubMed ID: 26398933	2015
Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model. Disease models & mechanisms\| PubMed ID: 26794131	2016
Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis. Scientific reports\| PubMed ID: 26847702	2016
Pleiotropic action of CpG-ODN on endothelium and macrophages attenuates angiogenesis through distinct pathways. Scientific reports\| PubMed ID: 27558877	2016
Interleukin-33 regulates tissue remodelling and inhibits angiogenesis in the eye. The Journal of pathology\| PubMed ID: 27701734	2017
Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course. Lung\| PubMed ID: 27864635	2017
An anti-TNF-α antibody mimetic to treat ocular inflammation. Scientific reports\| PubMed ID: 27874029	2016
Re-programming immunosurveillance in persistent non-infectious ocular inflammation. Progress in retinal and eye research\| PubMed ID: 29530739	2018
A Perspective of AMD Through the Eyes of Immunology. Investigative ophthalmology & visual science\| PubMed ID: 30025105	2018
The Bromodomain and Extra-Terminal Protein Inhibitor OTX015 Suppresses T Helper Cell Proliferation and Differentiation. Current molecular medicine\| PubMed ID: 30683020	2018
Müller Cells Stabilize Microvasculature through Hypoxic Preconditioning. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 30921506	2019
Restoring retinal neurovascular health via substance P. Experimental cell research\| PubMed ID: 30995434	2019
Corrigendum to "Restoring retinal neurovascular health via substance P" [Exp. Cell Res. (2019)]. Experimental cell research\| PubMed ID: 31284947	2019
Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood-Retinal Barrier Integrity In Vitro. Translational vision science & technology\| PubMed ID: 31667008	2019
Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 31981492	2020
Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Frontiers in immunology\| PubMed ID: 31993055	2019
Intravenous indocyanine green dye is insufficient for robust immune cell labelling in the human retina. PloS one\| PubMed ID: 32053618	2020
Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment. Journal of cellular and molecular medicine\| PubMed ID: 32141716	2020
Treatment with interleukin-33 is non-toxic and protects retinal pigment epithelium in an ageing model of outer retinal degeneration. Journal of cellular and molecular medicine\| PubMed ID: 33079455	2020
Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration. Journal of neuroinflammation\| PubMed ID: 33482879	2021
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses. Science translational medicine\| PubMed ID: 33568518	2021
Quantitative Assessment of Experimental Ocular Inflammatory Disease. Frontiers in immunology\| PubMed ID: 34220797	2021
Unravelling the therapeutic potential of IL-33 for atrophic AMD. Eye (London, England)\| PubMed ID: 34531552	2021