Dirk Bumann

Publications

• Revitalizing Antibiotic Discovery and Development Through in Vitro Modelling of In-patient Conditions
  Nature Microbiology. Jan, 2024  |   Pubmed ID: 38177300
• Zebrafish Larvae As an Model for Antimicrobial Activity Tests Against Intracellular
  Frontiers in Bioscience (Landmark Edition). May, 2023  |   Pubmed ID: 37258480
• Importance of Aspartyl Protease 5 in the Establishment of the Intracellular Niche During Acute and Chronic Infection of Toxoplasma Gondii
  Molecular Microbiology. Dec, 2022  |   Pubmed ID: 36210525
• Plant-Derived Catechols Are Substrates of TonB-Dependent Transporters and Sensitize Pseudomonas Aeruginosa to Siderophore-Drug Conjugates
  MBio. Aug, 2022  |   Pubmed ID: 35770947
• Making Antimicrobial Susceptibility Testing More Physiologically Relevant with Bicarbonate?
  Antimicrobial Agents and Chemotherapy. May, 2022  |   Pubmed ID: 35435706
• Tissue Compartmentalization Enables Persistence During Chemotherapy
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2021  |   Pubmed ID: 34911764
• Acquisition of Ionic Copper by the Bacterial Outer Membrane Protein OprC Through a Novel Binding Site
  PLoS Biology. Nov, 2021  |   Pubmed ID: 34762655
• Outer Membrane Permeability: Antimicrobials and Diverse Nutrients Bypass Porins in
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2021  |   Pubmed ID: 34326266
• Ferritin H Deficiency Deteriorates Cellular Iron Handling and Worsens Salmonella Typhimurium Infection by Triggering Hyperinflammation
  JCI Insight. Jul, 2021  |   Pubmed ID: 34236052
• Increased Production of Outer Membrane Vesicles by Salmonella Interferes with Complement-Mediated Innate Immune Attack
  MBio. Jun, 2021  |   Pubmed ID: 34061589
• Molecular Reprogramming and Phenotype Switching in Lead to High Antibiotic Persistence and Affect Therapy Success
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2021  |   Pubmed ID: 33574060
• Single-cell Reporters for Pathogen Responses to Antimicrobial Host Attacks
  Current Opinion in Microbiology. Feb, 2021  |   Pubmed ID: 32810800
• Regulation of Chaperone Function by Coupled Folding and Oligomerization
  Science Advances. Oct, 2020  |   Pubmed ID: 33087350
• Dynamics in Protein Translation Sustaining T Cell Preparedness
  Nature Immunology. Aug, 2020  |   Pubmed ID: 32632289
• Efficient Dual-negative Selection for Bacterial Genome Editing
  BMC Microbiology. May, 2020  |   Pubmed ID: 32448155
• Classical Activation of Macrophages Leads to Lipid Droplet Formation Without Fatty Acid Synthesis
  Frontiers in Immunology. 2020  |   Pubmed ID: 32132994
• Intestinal Epithelial NAIP/NLRC4 Restricts Systemic Dissemination of the Adapted Pathogen Salmonella Typhimurium Due to Site-specific Bacterial PAMP Expression
  Mucosal Immunology. May, 2020  |   Pubmed ID: 31953493
• Host Resistance Factor SLC11A1 Restricts Growth Through Magnesium Deprivation
  Science (New York, N.Y.). Nov, 2019  |   Pubmed ID: 31753999
• Antibiotic Chemotherapy Against Heterogeneous Pathogen Populations in Complex Host Tissues
  F1000Research. 2019  |   Pubmed ID: 31737252
• Non-specific Interference of Cobalt with Siderophore-dependent Iron Uptake Pathways
  Metallomics : Integrated Biometal Science. Nov, 2019  |   Pubmed ID: 31633703
• Dissecting Colistin Resistance Mechanisms in Extensively Drug-Resistant Acinetobacter Baumannii Clinical Isolates
  MBio. Jul, 2019  |   Pubmed ID: 31311879
• Publisher Correction: Definitions and Guidelines for Research on Antibiotic Persistence
  Nature Reviews. Microbiology. Jul, 2019  |   Pubmed ID: 31036919
• Definitions and Guidelines for Research on Antibiotic Persistence
  Nature Reviews. Microbiology. Jul, 2019  |   Pubmed ID: 30980069
• Single-Cell Metabolism and Stress Responses in Complex Host Tissues
  Microbiology Spectrum. Mar, 2019  |   Pubmed ID: 30953427
• Publisher Correction: Clonal Analysis of Salmonella-specific Effector T Cells Reveals Serovar-specific and Cross-reactive T Cell Responses
  Nature Immunology. Apr, 2019  |   Pubmed ID: 30862955
• Quantitative Contribution of Efflux to Multi-drug Resistance of Clinical Escherichia Coli and Pseudomonas Aeruginosa Strains
  EBioMedicine. Mar, 2019  |   Pubmed ID: 30852163
• Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance While Maintaining Anti-Pathogen Immunity
  Immunity. Jan, 2019  |   Pubmed ID: 30611611
• A Multidisciplinary Approach Toward Identification of Antibiotic Scaffolds for Acinetobacter Baumannii
  Structure (London, England : 1993). Feb, 2019  |   Pubmed ID: 30554842
• Getting Drugs Through Small Pores: Exploiting the Porins Pathway in Pseudomonas Aeruginosa
  ACS Infectious Diseases. Oct, 2018  |   Pubmed ID: 30039960
• Clonal Analysis of Salmonella-specific Effector T Cells Reveals Serovar-specific and Cross-reactive T Cell Responses
  Nature Immunology. Jul, 2018  |   Pubmed ID: 29925993
• The Hepcidin-ferroportin Axis Controls the Iron Content of Salmonella-containing Vacuoles in Macrophages
  Nature Communications. May, 2018  |   Pubmed ID: 29844422
• TonB-Dependent Receptor Repertoire of Pseudomonas Aeruginosa for Uptake of Siderophore-Drug Conjugates
  Antimicrobial Agents and Chemotherapy. Jun, 2018  |   Pubmed ID: 29555629
• Correction for Wu Et Al., "Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages Via Modulation of NF-κB Signaling"
  Infection and Immunity. Mar, 2018  |   Pubmed ID: 29463686
• Editorial Overview: Bacterial Systems Biology
  Current Opinion in Microbiology. Oct, 2017  |   Pubmed ID: 29241558
• Structural Basis for Maintenance of Bacterial Outer Membrane Lipid Asymmetry
  Nature Microbiology. Dec, 2017  |   Pubmed ID: 29038444
• Heterogeneity of Salmonella-host Interactions in Infected Host Tissues
  Current Opinion in Microbiology. Oct, 2017  |   Pubmed ID: 28988065
• Salmonella Utilizes Zinc To Subvert Antimicrobial Host Defense of Macrophages Via Modulation of NF-κB Signaling
  Infection and Immunity. Dec, 2017  |   Pubmed ID: 28874447
• Intracellular Salmonella Metabolism
  Cellular Microbiology. Oct, 2017  |   Pubmed ID: 28672057
• Myeloperoxidase Targets Oxidative Host Attacks to Salmonella and Prevents Collateral Tissue Damage
  Nature Microbiology. Jan, 2017  |   Pubmed ID: 28112722
• A Novel Genome-Editing Platform for Drug-Resistant Acinetobacter Baumannii Reveals an AdeR-Unrelated Tigecycline Resistance Mechanism
  Antimicrobial Agents and Chemotherapy. Dec, 2016  |   Pubmed ID: 27671072
• Combining Shigella Tn-seq Data with Gold-standard E. Coli Gene Deletion Data Suggests Rare Transitions Between Essential and Non-essential Gene Functionality
  BMC Microbiology. Sep, 2016  |   Pubmed ID: 27599549
• Catechol Siderophores Repress the Pyochelin Pathway and Activate the Enterobactin Pathway in Pseudomonas Aeruginosa: an Opportunity for Siderophore-antibiotic Conjugates Development
  Environmental Microbiology. Mar, 2016  |   Pubmed ID: 26718479
• Heterogeneous Host-pathogen Encounters: Act Locally, Think Globally
  Cell Host & Microbe. Jan, 2015  |   Pubmed ID: 25590757
• PLEKHM1 Regulates Salmonella-containing Vacuole Biogenesis and Infection
  Cell Host & Microbe. Jan, 2015  |   Pubmed ID: 25500191
• Fast Sampling Method for Mammalian Cell Metabolic Analyses Using Liquid Chromatography-mass Spectrometry
  Nature Protocols. Jan, 2015  |   Pubmed ID: 25474028
• Identification of Protective Antigens for Vaccination Against Systemic Salmonellosis
  Frontiers in Immunology. 2014  |   Pubmed ID: 25157252
• Phenotypic Variation of Salmonella in Host Tissues Delays Eradication by Antimicrobial Chemotherapy
  Cell. Aug, 2014  |   Pubmed ID: 25126781
• Shigella Reroutes Host Cell Central Metabolism to Obtain High-flux Nutrient Supply for Vigorous Intracellular Growth
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2014  |   Pubmed ID: 24958876
• The Central Metabolism Regulator EIIAGlc Switches Salmonella from Growth Arrest to Acute Virulence Through Activation of Virulence Factor Secretion
  Cell Reports. Jun, 2014  |   Pubmed ID: 24835993
• Caspase-11 Activation Requires Lysis of Pathogen-containing Vacuoles by IFN-induced GTPases
  Nature. May, 2014  |   Pubmed ID: 24739961
• Disparate Impact of Oxidative Host Defenses Determines the Fate of Salmonella During Systemic Infection in Mice
  Cell Host & Microbe. Jan, 2014  |   Pubmed ID: 24439899
• Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence
  PLoS Pathogens. 2013  |   Pubmed ID: 23633950
• Functional Identification of APIP As Human MtnB, a Key Enzyme in the Methionine Salvage Pathway
  PloS One. 2012  |   Pubmed ID: 23285211
• Immunity to Intracellular Salmonella Depends on Surface-associated Antigens
  PLoS Pathogens. 2012  |   Pubmed ID: 23093937
• Extensive in Vivo Resilience of Persistent Salmonella
  PloS One. 2012  |   Pubmed ID: 22911873
• Intestinal Inflammation Responds to Microbial Tissue Load Independent of Pathogen/non-pathogen Discrimination
  PloS One. 2012  |   Pubmed ID: 22586458
• Identification of Tumor-specific Salmonella Typhimurium Promoters and Their Regulatory Logic
  Nucleic Acids Research. Apr, 2012  |   Pubmed ID: 22140114
• Salmonella-induced Mucosal Lectin RegIIIβ Kills Competing Gut Microbiota
  PloS One. 2011  |   Pubmed ID: 21694778
• A Community Effort Towards a Knowledge-base and Mathematical Model of the Human Pathogen Salmonella Typhimurium LT2
  BMC Systems Biology. 2011  |   Pubmed ID: 21244678
• Pathogen Proteomes During Infection: A Basis for Infection Research and Novel Control Strategies
  Journal of Proteomics. Oct, 2010  |   Pubmed ID: 20797457
• System-level Analysis of Salmonella Metabolism During Infection
  Current Opinion in Microbiology. Oct, 2009  |   Pubmed ID: 19744878
• Has Nature Already Identified All Useful Antibacterial Targets?
  Current Opinion in Microbiology. Oct, 2008  |   Pubmed ID: 18804175