Gary S. Sayler The Joint Institute for Biological Sciences Oak Ridge National Laboratory Biography Publications Institution JoVE Articles Gary S. Sayler has not added a biography. If you are Gary S. Sayler and would like to personalize this page please email our Author Liaison for assistance. Publications C60 Reduces the Bioavailability of Mercury in Aqueous Solutions Chemosphere. Oct, 2013 | Pubmed ID: 24125709 Commercial DNA Extraction Kits Impact Observed Microbial Community Composition in Permafrost Samples FEMS Microbiology Ecology. Sep, 2013 | Pubmed ID: 24102625 An Overview on the Marine Neurotoxin, Saxitoxin: Genetics, Molecular Targets, Methods of Detection and Ecological Functions Marine Drugs. Apr, 2013 | Pubmed ID: 23535394 Paralytic Shellfish Toxins Inhibit Copper Uptake in Chlamydomonas Reinhardtii Environmental Toxicology and Chemistry / SETAC. Jun, 2013 | Pubmed ID: 23423950 Complete Genome Sequence of Thauera Aminoaromatica Strain MZ1T Standards in Genomic Sciences. Jul, 2012 | Pubmed ID: 23407619 Unsealed Tubewells Lead to Increased Fecal Contamination of Drinking Water Journal of Water and Health. Dec, 2012 | Pubmed ID: 23165714 Comparison of Fecal Indicators with Pathogenic Bacteria and Rotavirus in Groundwater The Science of the Total Environment. Jun, 2012 | Pubmed ID: 22705866 Global Gene Expression in Larval Zebrafish (Danio Rerio) Exposed to Selective Serotonin Reuptake Inhibitors (fluoxetine and Sertraline) Reveals Unique Expression Profiles and Potential Biomarkers of Exposure Environmental Pollution (Barking, Essex : 1987). Aug, 2012 | Pubmed ID: 22575097 Pseudomonas Fluorescens HK44: Lessons Learned from a Model Whole-cell Bioreporter with a Broad Application History Sensors (Basel, Switzerland). 2012 | Pubmed ID: 22438725 Lack of Androgenicity and Estrogenicity of the Three Monomers Used in Eastman's Tritan™ Copolyesters Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Jun, 2012 | Pubmed ID: 22343188 在酵母中对铜的吸收的抑制作用作为一个潜在的分子目标瘫痪贝类中毒的揭示了铜的农用运输车 Ctr1p。 Environmental Science & Technology. Feb, 2012 | Pubmed ID: 22304436 Dissolution and Transport of Coal Tar Compounds in Fractured Clay-rich Residuum Journal of Hazardous Materials. Feb, 2012 | Pubmed ID: 22209208 Guest Comment: Environmental Genomics Focus Issue Environmental Science & Technology. Jan, 2012 | Pubmed ID: 22208704 Implications of Fecal Bacteria Input from Latrine-polluted Ponds for Wells in Sandy Aquifers Environmental Science & Technology. Feb, 2012 | Pubmed ID: 22191430 Pathogen Detection Using Engineered Bacteriophages Analytical and Bioanalytical Chemistry. Apr, 2012 | Pubmed ID: 22101465 Horizontal Transfer of PAH Catabolism Genes in Mycobacterium: Evidence from Comparative Genomics and Isolated Pyrene-degrading Bacteria Environmental Science & Technology. Jan, 2012 | Pubmed ID: 21899303 Detection of Dichloromethane with a Bioluminescent (lux) Bacterial Bioreporter Journal of Industrial Microbiology & Biotechnology. Jan, 2012 | Pubmed ID: 21688172 In Vivo Bioluminescent Imaging (BLI): Noninvasive Visualization and Interrogation of Biological Processes in Living Animals Sensors (Basel, Switzerland). 2011 | Pubmed ID: 22346573 Draft Genome Sequence of the Polycyclic Aromatic Hydrocarbon-degrading, Genetically Engineered Bioluminescent Bioreporter Pseudomonas Fluorescens HK44 Journal of Bacteriology. Sep, 2011 | Pubmed ID: 21742869 Impact of Population and Latrines on Fecal Contamination of Ponds in Rural Bangladesh The Science of the Total Environment. Aug, 2011 | Pubmed ID: 21632095 Comparison of Human Optimized Bacterial Luciferase, Firefly Luciferase, and Green Fluorescent Protein for Continuous Imaging of Cell Culture and Animal Models Journal of Biomedical Optics. Apr, 2011 | Pubmed ID: 21529093 全球基因表达谱的幼虫斑马鱼暴露于微囊藻毒素-LR 和微囊藻揭示了蓝藻的内分泌干扰作用。 Environmental Science & Technology. Mar, 2011 | Pubmed ID: 21280650 The Association Between NC60 and 17α-ethinylestradiol (EE2) Decreases EE2 Bioavailability in Zebrafish and Alters Nanoaggregate Characteristics Nanotoxicology. Sep, 2011 | Pubmed ID: 20969539 Efficacy of Hollow-fiber Ultrafiltration for Microbial Sampling in Groundwater Ground Water. Jan-Feb, 2011 | Pubmed ID: 20497484 Bioenergy Sustainability in China: Potential and Impacts Environmental Management. Oct, 2010 | Pubmed ID: 20838792 Autonomous Bioluminescent Expression of the Bacterial Luciferase Gene Cassette (lux) in a Mammalian Cell Line PloS One. 2010 | Pubmed ID: 20805991 Transcription Levels (amoA MRNA-based) and Population Dominance (amoA Gene-based) of Ammonia-oxidizing Bacteria Journal of Industrial Microbiology & Biotechnology. Jul, 2010 | Pubmed ID: 20440533 China-U.S. Workshop on Biotechnology of Bioenergy Plants Ecotoxicology (London, England). Jan, 2010 | Pubmed ID: 19967444 Reporter Proteins in Whole-cell Optical Bioreporter Detection Systems, Biosensor Integrations, and Biosensing Applications Sensors (Basel, Switzerland). 2009 | Pubmed ID: 22291559 EPA at 40: Bringing Environmental Protection into the 21st Century Environmental Science & Technology. Dec, 2009 | Pubmed ID: 19943637 转录分析酿酒酵母细胞暴露在瘫痪贝类中毒。 Environmental Science & Technology. Aug, 2009 | Pubmed ID: 19731715 伊利湖沉积物中的多环芳香烃生物降解基因型: 芘降解分支杆菌广泛的地域分配的证据。 Environmental Science & Technology. May, 2009 | Pubmed ID: 19544841 Microbial Community Structure and Biodegradation Activity of Particle-associated Bacteria in a Coal Tar Contaminated Creek Environmental Science & Technology. May, 2009 | Pubmed ID: 19534112 Factors Influencing the Persistence of Fecal Bacteroides in Stream Water Journal of Environmental Quality. May-Jun, 2009 | Pubmed ID: 19398520 Use of Gene Probes to Assess the Impact and Effectiveness of Aerobic in Situ Bioremediation of TCE Archives of Microbiology. Mar, 2009 | Pubmed ID: 19034430 筛选潜在荷尔蒙活跃化学品使用发光酵母 Bioreporters。 Toxicological Sciences : an Official Journal of the Society of Toxicology. Jan, 2009 | Pubmed ID: 18996888 Inducible RNA Interference-mediated Gene Silencing Using Nanostructured Gene Delivery Arrays ACS Nano. Jan, 2008 | Pubmed ID: 19206549 Genome Sequence of the Bacteroides Fragilis Phage ATCC 51477-B1 Virology Journal. 2008 | Pubmed ID: 18710568 Temporal Variation and Persistence of Bacteria in Streams Journal of Environmental Quality. Jul-Aug, 2008 | Pubmed ID: 18574188 Response of Nitrobacter Spp. Ribosomal Gene and Transcript Abundance Following Nitrite Starvation and Exposure to Mechanistically Distinct Inhibitors Environmental Science & Technology. Feb, 2008 | Pubmed ID: 18323120 Bacteriophage-amplified Bioluminescent Sensing of Escherichia Coli O157:H7 Analytical and Bioanalytical Chemistry. May, 2008 | Pubmed ID: 18188543 不稳定的细菌荧光动态基因表达研究。 Systems and Synthetic Biology. Mar, 2007 | Pubmed ID: 19003433 Detection of Nitrate/nitrite Bioavailability in Wastewater Using a LuxCDABE-based Klebsiella Oxytoca Bioluminescent Bioreporter Journal of Microbiology and Biotechnology. Aug, 2007 | Pubmed ID: 18051593 Comparative Quantitative Prevalence of Mycobacteria and Functionally Abundant NidA, NahAc, and NagAc Dioxygenase Genes in Coal Tar Contaminated Sediments Environmental Science & Technology. Aug, 2007 | Pubmed ID: 17822112 酿酒酵母 BLYAS,新的发光 Bioreporter 雄激素化合物的检测。 Applied and Environmental Microbiology. Oct, 2007 | Pubmed ID: 17675419 Attributing Effects of Aqueous C60 Nano-aggregates to Tetrahydrofuran Decomposition Products in Larval Zebrafish by Assessment of Gene Expression Environmental Health Perspectives. Jul, 2007 | Pubmed ID: 17637923 Efficacy of Bacteroides Measurements for Reducing the Statistical Uncertainty Associated with Hydrologic Flow and Fecal Loads in a Mixed Use Watershed Journal of Environmental Quality. Sep-Oct, 2007 | Pubmed ID: 17636294 Bacteriophage-based Bioluminescent Bioreporter for the Detection of Escherichia Coli 0157:H7 Journal of Food Protection. Jun, 2007 | Pubmed ID: 17612068 Concurrent Nitrite Oxidation and Aerobic Denitrification in Activated Sludge Exposed to Volatile Fatty Acids Biotechnology and Bioengineering. Aug, 2007 | Pubmed ID: 17304559 Distribution and Transport of Coal Tar-derived PAHs in Fine-grained Residuum Chemosphere. Jun, 2007 | Pubmed ID: 17303216 Quantitative Analysis of EDC-condensed DNA on Vertically Aligned Carbon Nanofiber Gene Delivery Arrays Biotechnology and Bioengineering. Jul, 2007 | Pubmed ID: 17154308 在培养上清液使用全细胞 Bioreporter N-(3-oxo-hexanoyl)-L-homoserine 内酯的直接量化。 Journal of Microbiological Methods. Jan, 2007 | Pubmed ID: 16916554 Escherichia Coli Loading at or Near Base Flow in a Mixed-use Watershed Journal of Environmental Quality. Nov-Dec, 2006 | Pubmed ID: 17071895 Volatile Fatty Acid Impacts on Nitrite Oxidation and Carbon Dioxide Fixation in Activated Sludge Water Research. Feb, 2006 | Pubmed ID: 16436292 In Vitro Immune Toxicity of Depleted Uranium: Effects on Murine Macrophages, CD4+ T Cells, and Gene Expression Profiles Environmental Health Perspectives. Jan, 2006 | Pubmed ID: 16393663 Use of Saccharomyces Cerevisiae BLYES Expressing Bacterial Bioluminescence for Rapid, Sensitive Detection of Estrogenic Compounds Applied and Environmental Microbiology. Aug, 2005 | Pubmed ID: 16085836 Codon Optimization of Bacterial Luciferase (lux) for Expression in Mammalian Cells Journal of Industrial Microbiology & Biotechnology. Mar, 2005 | Pubmed ID: 15761767 Evaluation of Polycyclic Aromatic Hydrocarbons in the Activation of Early Growth Response-1 and Peroxisome Proliferator Activated Receptors Toxicological Sciences : an Official Journal of the Society of Toxicology. May, 2005 | Pubmed ID: 15716483 Emergence of Competitive Dominant Ammonia-oxidizing Bacterial Populations in a Full-scale Industrial Wastewater Treatment Plant Applied and Environmental Microbiology. Feb, 2005 | Pubmed ID: 15691975 雌激素含量奶牛和猪的废物。 Environmental Science & Technology. Jul, 2004 | Pubmed ID: 15296306 Analysis and Glycosyl Composition of the Exopolysaccharide Isolated from the Floc-forming Wastewater Bacterium Thauera Sp. MZ1T Environmental Microbiology. Aug, 2004 | Pubmed ID: 15250880 类似于青枯株 U2 NagAc 双加氧酶基因的丰度与萘煤焦油污染淡水沉积物中的浓度相关。 Applied and Environmental Microbiology. Jul, 2004 | Pubmed ID: 15240274 Frequency Domain Chemical Langevin Analysis of Stochasticity in Gene Transcriptional Regulation Journal of Theoretical Biology. Aug, 2004 | Pubmed ID: 15234205 Emerging Foundations: Nano-engineering and Bio-microelectronics for Environmental Biotechnology Current Opinion in Microbiology. Jun, 2004 | Pubmed ID: 15196494 Evaluation of a Plasmid-based 16S-23S RDNA Intergenic Spacer Region Array for Analysis of Microbial Diversity in Industrial Wastewater Journal of Microbiological Methods. Apr, 2004 | Pubmed ID: 15003691 Expression of the Photorhabdus Luminescens Lux Genes (luxA, B, C, D, and E) in Saccharomyces Cerevisiae FEMS Yeast Research. Dec, 2003 | Pubmed ID: 14654435 Power Analysis for Real-time PCR Quantification of Genes in Activated Sludge and Analysis of the Variability Introduced by DNA Extraction Applied and Environmental Microbiology. Nov, 2003 | Pubmed ID: 14602618 Analysis of Noise in Quorum Sensing Omics : a Journal of Integrative Biology. 2003 | Pubmed ID: 14583119 Environmental Application of Array Technology: Promise, Problems and Practicalities Current Opinion in Biotechnology. Jun, 2003 | Pubmed ID: 12849785 Frequency Domain Analysis of Noise in Autoregulated Gene Circuits Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12671069 Real-time PCR Quantification of Nitrifying Bacteria in a Municipal Wastewater Treatment Plant Environmental Science & Technology. Jan, 2003 | Pubmed ID: 12564907 Integrated CMOS Photodetectors and Signal Processing for Very Low-level Chemical Sensing with the Bioluminescent Bioreporter Integrated Circuit Sensors and Actuators. B, Chemical. Jun, 2002 | Pubmed ID: 12238524 多氯联苯的体外雌激素受体结合: 衡量活动和重组酵母测定中的羟基化代谢物的检测。 Toxicology and Applied Pharmacology. May, 2002 | Pubmed ID: 12009855 Long PCR-amplified RDNA for PCR-RFLP- and Rep-PCR-based Approaches to Recognize Closely Related Microbial Species Journal of Microbiological Methods. May, 2002 | Pubmed ID: 11869797 Quantification of Nitrosomonas Oligotropha-like Ammonia-oxidizing Bacteria and Nitrospira Spp. from Full-scale Wastewater Treatment Plants by Competitive PCR Applied and Environmental Microbiology. Jan, 2002 | Pubmed ID: 11772633 自主的生物发光哺乳动物细胞连续和实时监测细胞毒性 Tingting Xu1, Dan M. Close2, James D. Webb3, Steven A. Ripp2,3, Gary S. Sayler1,2,3 1The Joint Institute for Biological Sciences, Oak Ridge National Laboratory, 2490 BioTech, Inc., 3The Center for Environmental Biotechnology, The University of Tennessee, Knoxville JoVE 50972 Biology
自主的生物发光哺乳动物细胞连续和实时监测细胞毒性 Tingting Xu1, Dan M. Close2, James D. Webb3, Steven A. Ripp2,3, Gary S. Sayler1,2,3 1The Joint Institute for Biological Sciences, Oak Ridge National Laboratory, 2490 BioTech, Inc., 3The Center for Environmental Biotechnology, The University of Tennessee, Knoxville JoVE 50972 Biology