Holger Jahr Department of Orthopedic Surgery Maastricht UMC+ Biography Publications Institution JoVE Articles Holger Jahr has not added a biography. If you are Holger Jahr and would like to personalize this page please email our Author Liaison for assistance. Publications The Antimicrobial Peptide Human Beta-Defensin-3 Is Induced by Platelet-Released Growth Factors in Primary Keratinocytes Mediators of Inflammation. 2017 | Pubmed ID: 28811680 Platelet-Released Growth Factors Induce Differentiation of Primary Keratinocytes Mediators of Inflammation. 2017 | Pubmed ID: 28808357 The Protective Effect of Platelet Released Growth Factors and Bone Augmentation (Bio-Oss(®)) on Ethanol Impaired Osteoblasts Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. Jul, 2017 | Pubmed ID: 28774818 Functional in Situ Assessment of Human Articular Cartilage Using MRI: a Whole-knee Joint Loading Device Biomechanics and Modeling in Mechanobiology. Jul, 2017 | Pubmed ID: 28685238 Platelet-released Growth Factors Induce Psoriasin in Keratinocytes: Implications for the Cutaneous Barrier Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. Sep, 2017 | Pubmed ID: 28552640 Functional MR Imaging Mapping of Human Articular Cartilage Response to Loading Radiology. Feb, 2017 | Pubmed ID: 27564133 Ex Vivo Quantitative Multiparametric MRI Mapping of Human Meniscus Degeneration Skeletal Radiology. Dec, 2016 | Pubmed ID: 27639388 Effect of Platelet Mediator Concentrate (PMC) on Achilles Tenocytes: an in Vitro Study BMC Musculoskeletal Disorders. Jul, 2016 | Pubmed ID: 27448409 Polarization-sensitive Optical Coherence Tomography-based Imaging, Parameterization, and Quantification of Human Cartilage Degeneration Journal of Biomedical Optics. Jul, 2016 | Pubmed ID: 27447953 Cell Surface Syndecan-1 Contributes to Binding and Function of Macrophage Migration Inhibitory Factor (MIF) on Epithelial Tumor Cells Biochimica Et Biophysica Acta. Apr, 2016 | Pubmed ID: 26852939 Quantitative OCT and MRI Biomarkers for the Differentiation of Cartilage Degeneration Skeletal Radiology. Apr, 2016 | Pubmed ID: 26783011 Towards Optical Coherence Tomography-based Elastographic Evaluation of Human Cartilage Journal of the Mechanical Behavior of Biomedical Materials. Mar, 2016 | Pubmed ID: 26700573 Detecting Early Stage Osteoarthritis by Optical Coherence Tomography? Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 2015 | Pubmed ID: 26862954 HDACi and Nrf2: Not from Alpha to Omega but from Acetylation to OA Arthritis Research & Therapy. Dec, 2015 | Pubmed ID: 26714479 3D Human Cartilage Surface Characterization by Optical Coherence Tomography Physics in Medicine and Biology. Oct, 2015 | Pubmed ID: 26394374 A Cytoplasmic C-terminal Fragment of Syndecan-1 is Generated by Sequential Proteolysis and Antagonizes Syndecan-1 Dependent Lung Tumor Cell Migration Oncotarget. Oct, 2015 | Pubmed ID: 26378057 Abrasion Arthroplasty Increases Mesenchymal Stem Cell Content of Postoperative Joint Effusions BMC Musculoskeletal Disorders. Sep, 2015 | Pubmed ID: 26364138 Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography BioMed Research International. 2015 | Pubmed ID: 26229959 Optical Coherence Tomography-based Parameterization and Quantification of Articular Cartilage Surface Integrity Biomedical Optics Express. Jul, 2015 | Pubmed ID: 26203369 A Transmembrane C-terminal Fragment of Syndecan-1 is Generated by the Metalloproteinase ADAM17 and Promotes Lung Epithelial Tumor Cell Migration and Lung Metastasis Formation Cellular and Molecular Life Sciences : CMLS. Oct, 2015 | Pubmed ID: 25912030 Physicochemical and Biomechanical Stimuli in Cell-based Articular Cartilage Repair Current Rheumatology Reports. Mar, 2015 | Pubmed ID: 25828845 Three-dimensional Imaging and Analysis of Human Cartilage Degeneration Using Optical Coherence Tomography Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2015 | Pubmed ID: 25641346 Osteostatin-coated Porous Titanium Can Improve Early Bone Regeneration of Cortical Bone Defects in Rats Tissue Engineering. Part A. May, 2015 | Pubmed ID: 25627039 Mechanical Forces Induce Changes in VEGF and VEGFR-1/sFlt-1 Expression in Human Chondrocytes International Journal of Molecular Sciences. Sep, 2014 | Pubmed ID: 25257525 Nrf2 Deficiency Impairs Fracture Healing in Mice Calcified Tissue International. Oct, 2014 | Pubmed ID: 25096517 Morphometric Grading of Osteoarthritis by Optical Coherence Tomography--an Ex Vivo Study Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Oct, 2014 | Pubmed ID: 24992396 Role of Platelet-released Growth Factors in Detoxification of Reactive Oxygen Species in Osteoblasts Bone. Aug, 2014 | Pubmed ID: 24798492 GREM1, FRZB and DKK1 MRNA Levels Correlate with Osteoarthritis and Are Regulated by Osteoarthritis-associated Factors Arthritis Research & Therapy. Sep, 2013 | Pubmed ID: 24286177 A Universal Method for Sequential Immunofluorescent Analysis of Chromatin and Chromatin-associated Proteins on Chromosome Spreads Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. Aug, 2013 | Pubmed ID: 23896649 Enhanced Bone Regeneration of Cortical Segmental Bone Defects Using Porous Titanium Scaffolds Incorporated with Colloidal Gelatin Gels for Time- and Dose-controlled Delivery of Dual Growth Factors Tissue Engineering. Part A. Dec, 2013 | Pubmed ID: 23822814 Hsp90 Inhibition Protects Against Biomechanically Induced Osteoarthritis in Rats Arthritis and Rheumatism. Aug, 2013 | Pubmed ID: 23666904 Selective Laser Melting-produced Porous Titanium Scaffolds Regenerate Bone in Critical Size Cortical Bone Defects Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2013 | Pubmed ID: 23255164 Unfocused Extracorporeal Shock Waves Induce Anabolic Effects in Osteoporotic Rats Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2013 | Pubmed ID: 23239548 Osmolarity Determines the in Vitro Chondrogenic Differentiation Capacity of Progenitor Cells Via Nuclear Factor of Activated T-cells 5 Bone. Mar, 2013 | Pubmed ID: 23219947 Inhibiting Calcineurin Activity Under Physiologic Tonicity Elevates Anabolic but Suppresses Catabolic Chondrocyte Markers Arthritis and Rheumatism. Jun, 2012 | Pubmed ID: 22231955 Calcineurin/nuclear Factor of Activated T Cells (NFAT) Signaling in Cobalt-chromium-molybdenum (CoCrMo) Particles-induced Tumor Necrosis Factor-α (TNFα) Secretion in MLO-Y4 Osteocytes Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Dec, 2011 | Pubmed ID: 21557302 A Role for Aurora C in the Chromosomal Passenger Complex During Human Preimplantation Embryo Development Human Reproduction (Oxford, England). Jul, 2011 | Pubmed ID: 21493633 Clinically Translatable Cell Tracking and Quantification by MRI in Cartilage Repair Using Superparamagnetic Iron Oxides PloS One. Feb, 2011 | Pubmed ID: 21373640 Differences in Cartilage-forming Capacity of Expanded Human Chondrocytes from Ear and Nose and Their Gene Expression Profiles Cell Transplantation. 2011 | Pubmed ID: 21054934 Stimulation of Osteogenic Differentiation in Human Osteoprogenitor Cells by Pulsed Electromagnetic Fields: an in Vitro Study BMC Musculoskeletal Disorders. Aug, 2010 | Pubmed ID: 20731873 Physiological Tonicity Improves Human Chondrogenic Marker Expression Through Nuclear Factor of Activated T-cells 5 in Vitro Arthritis Research & Therapy. 2010 | Pubmed ID: 20492652 Estrogen Modulates Iodoacetate-induced Gene Expression in Bovine Cartilage Explants Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. May, 2010 | Pubmed ID: 19953602 Stretch-induced Inhibition of Wnt/beta-catenin Signaling in Mineralizing Osteoblasts Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Mar, 2010 | Pubmed ID: 19780202 Fibroblast Growth Factor Receptors in in Vitro and in Vivo Chondrogenesis: Relating Tissue Engineering Using Adult Mesenchymal Stem Cells to Embryonic Development Tissue Engineering. Part A. Feb, 2010 | Pubmed ID: 19728793 The Role of Hypoxia in Bone Marrow-derived Mesenchymal Stem Cells: Considerations for Regenerative Medicine Approaches Tissue Engineering. Part B, Reviews. Apr, 2010 | Pubmed ID: 19698058 Calcineurin Inhibitors Promote Chondrogenic Marker Expression of Dedifferentiated Human Adult Chondrocytes Via Stimulation of Endogenous TGFbeta1 Production Tissue Engineering. Part A. Jan, 2010 | Pubmed ID: 19604038 Chondrogenic Priming of Human Bone Marrow Stromal Cells: a Better Route to Bone Repair? Tissue Engineering. Part C, Methods. Jun, 2009 | Pubmed ID: 19505182 In Vitro Model to Study Chondrogenic Differentiation in Tendinopathy The American Journal of Sports Medicine. Jun, 2009 | Pubmed ID: 19279223 Tendon Degeneration is Not Mediated by Regulation of Toll-like Receptors 2 and 4 in Human Tenocytes Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Aug, 2009 | Pubmed ID: 19148938 Angiogenic Capacity of Human Adipose-derived Stromal Cells During Adipogenic Differentiation: an in Vitro Study Tissue Engineering. Part A. Feb, 2009 | Pubmed ID: 18652540 Control of Oxygen Tension and PH in a Bioreactor for Cartilage Tissue Engineering Bio-medical Materials and Engineering. 2008 | Pubmed ID: 19065034 Obestatin Induction of Early-response Gene Expression in Gastrointestinal and Adipose Tissues and the Mediatory Role of G Protein-coupled Receptor, GPR39 Molecular Endocrinology (Baltimore, Md.). Jun, 2008 | Pubmed ID: 18337590 Effects of Iron Oxide Incorporation for Long Term Cell Tracking on MSC Differentiation in Vitro and in Vivo Biochemical and Biophysical Research Communications. May, 2008 | Pubmed ID: 18336785 Can Platelet-rich Plasma Enhance Tendon Repair? A Cell Culture Study The American Journal of Sports Medicine. Jun, 2008 | Pubmed ID: 18326832 Achilles Tendinosis: Changes in Biochemical Composition and Collagen Turnover Rate The American Journal of Sports Medicine. Sep, 2007 | Pubmed ID: 17478653 Intrinsic Differentiation Potential of Adolescent Human Tendon Tissue: an In-vitro Cell Differentiation Study BMC Musculoskeletal Disorders. Feb, 2007 | Pubmed ID: 17319938 Stretch-induced Modulation of Matrix Metalloproteinases in Mineralizing Osteoblasts Via Extracellular Signal-regulated Kinase-1/2 Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jul, 2006 | Pubmed ID: 16705736 Identification of Acid-sensing Ion Channels in Bone Biochemical and Biophysical Research Communications. Nov, 2005 | Pubmed ID: 16185661 Tuning Haptotropic Rearrangements of Arene-chromium Complexes: Steric and Electronic Effects of Phosphorus Coligands Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2005 | Pubmed ID: 16003815 Considerations on the Use of Ear Chondrocytes As Donor Chondrocytes for Cartilage Tissue Engineering Biorheology. 2004 | Pubmed ID: 15299273 Tunable Haptotropic Metal Migration in Fused Arenes: Towards Organometallic Switches Chemical Record (New York, N.Y.). 2004 | Pubmed ID: 15073874 Controlled Haptotropic Rearrangements--towards a Stereospecific Molecular Switch Based on Chiral Arene Chromium Complexes Chemical Communications (Cambridge, England). Dec, 2003 | Pubmed ID: 14680214 Visualizando a angiogênese por Multiphoton microscopia In Vivo no andaime de 3D-PLGA/nhập geneticamente modificado para raspagem crítico reparo de defeito ósseo Jian Li1, Holger Jahr2,3, Wei Zheng4, Pei-Gen Ren1 1Center for Translational Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 2Department of Orthopedic Surgery, Maastricht UMC+, 3Department of Orthopaedic Surgery, University Hospital RWTH, 4Research Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences JoVE 55381 Bioengineering
Visualizando a angiogênese por Multiphoton microscopia In Vivo no andaime de 3D-PLGA/nhập geneticamente modificado para raspagem crítico reparo de defeito ósseo Jian Li1, Holger Jahr2,3, Wei Zheng4, Pei-Gen Ren1 1Center for Translational Medicine Research and Development, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 2Department of Orthopedic Surgery, Maastricht UMC+, 3Department of Orthopaedic Surgery, University Hospital RWTH, 4Research Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences JoVE 55381 Bioengineering