Hynek Wichterle

Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University

Affiliated withCollege of Physicians and Surgeons, Columbia University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 197	2010

Other Publications

Article	Year
Directed differentiation of embryonic stem cells into motor neurons. Cell\| PubMed ID: 12176325	2002
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists. Journal of biology\| PubMed ID: 12437772	2002
Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12515855	2003
Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12679522	2003
A requirement for retinoic acid-mediated transcriptional activation in ventral neural patterning and motor neuron specification. Neuron\| PubMed ID: 14527435	2003
Functional properties of motoneurons derived from mouse embryonic stem cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15356197	2004
New neurons follow the flow of cerebrospinal fluid in the adult brain. Science (New York, N.Y.)\| PubMed ID: 16410488	2006
Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16432183	2006
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16914688	2006
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nature neuroscience\| PubMed ID: 17435755	2007
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science (New York, N.Y.)\| PubMed ID: 18669821	2008
Differentiation of mouse embryonic stem cells to spinal motor neurons. Current protocols in stem cell biology\| PubMed ID: 18770634	2008
Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19089356	2009
Combined microfluidics/protein patterning platform for pharmacological interrogation of axon pathfinding. Lab on a chip\| PubMed ID: 20358107	2010
What can pluripotent stem cells teach us about neurodegenerative diseases? Nature neuroscience\| PubMed ID: 20581816	2010
Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation. Cell stem cell\| PubMed ID: 20804971	2010
Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron\| PubMed ID: 20826310	2010
Programming embryonic stem cells to neuronal subtypes. Current opinion in neurobiology\| PubMed ID: 20970319	2011
MicroRNA regulation of neural stem cells and neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21068294	2010
Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis. Genome biology\| PubMed ID: 21232103	2011
A functionally characterized test set of human induced pluripotent stem cells. Nature biotechnology\| PubMed ID: 21293464	2011
Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop. Neuron\| PubMed ID: 21338882	2011
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell\| PubMed ID: 21924763	2011
Embryonic stem cell-based mapping of developmental transcriptional programs. Nature methods\| PubMed ID: 22081127	2011
Concentration-dependent requirement for local protein synthesis in motor neuron subtype-specific response to axon guidance cues. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22279234	2012