Karen Ocorr

Development and Aging Program, The Sanford Burnham Institute for Medical Research

Affiliated withThe Sanford Burnham Institute for Medical Research

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 58	2009
Publication title Cited by 106	2009
Publication title Cited by 108	2009

Other Publications

Article	Year
The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16882722	2006
Age-related cardiac disease model of Drosophila. Mechanisms of ageing and development\| PubMed ID: 17125816	2007
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360457	2007
Genetic control of heart function and aging in Drosophila. Trends in cardiovascular medicine\| PubMed ID: 17574126	2007
Genetic variation for cardiac dysfunction in Drosophila. PloS one\| PubMed ID: 17622346	2007
ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway. Biochemical and biophysical research communications\| PubMed ID: 17910948	2007
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. Molecular biology of the cell\| PubMed ID: 18045988	2008
Drosophila aging 2006/2007. Experimental gerontology\| PubMed ID: 18061385	2008
The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. The Journal of experimental biology\| PubMed ID: 18083727	2008
ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway. Molecular and cellular biochemistry\| PubMed ID: 18084723	2008
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. Aging cell\| PubMed ID: 18221418	2008
A novel human BTB-kelch protein KLHL31, strongly expressed in muscle and heart, inhibits transcriptional activities of TRE and SRE. Molecules and cells\| PubMed ID: 18719355	2008
Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19074289	2008
Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies. Developmental biology\| PubMed ID: 19233157	2009
A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. BioTechniques\| PubMed ID: 19317655	2009
d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging cell\| PubMed ID: 19594484	2009
Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner. PloS one\| PubMed ID: 19718456	2009
Drug discovery through functional screening in the Drosophila heart. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19718521	2009
KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1. BMB reports\| PubMed ID: 20132730	2010
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science (New York, N.Y.)\| PubMed ID: 20203043	2010
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell\| PubMed ID: 20371351	2010
The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development. Molecular biology reports\| PubMed ID: 20383585	2011
SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity. BMB reports\| PubMed ID: 20510020	2010
High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell metabolism\| PubMed ID: 21035763	2010
Drosophila as a model to study cardiac aging. Experimental gerontology\| PubMed ID: 21130861	2011
Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes & development\| PubMed ID: 21245170	2011
Cloning and characterization of the cardiac-specific Lrrc10 promoter. BMB reports\| PubMed ID: 21345312	2011
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. The Journal of cell biology\| PubMed ID: 21690310	2011
ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21719711	2011
The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. PloS one\| PubMed ID: 21799905	2011
Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. PLoS genetics\| PubMed ID: 22072978	2011
BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart rhythm : the official journal of the Heart Rhythm Society\| PubMed ID: 22138472	2011