Karen Oegema

Ludwig Institute for Cancer Research, San Diego

Affiliated withLudwig Institute for Cancer Research, San Diego University of California, San Diego

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2019

Other Publications

Article	Year
Closing the GAP: a role for a RhoA GAP in cytokinesis. Molecular cell\| PubMed ID: 12718869	2003
The minus end in sight. Current biology : CB\| PubMed ID: 12906817	2003
Centriole assembly requires both centriolar and pericentriolar material proteins. Developmental cell\| PubMed ID: 15572125	2004
The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation. Current biology : CB\| PubMed ID: 15854912	2005
Distinct roles for two C. elegans anillins in the gonad and early embryo. Development (Cambridge, England)\| PubMed ID: 15930113	2005
A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. The Journal of cell biology\| PubMed ID: 16247027	2005
Molecular analysis of mitotic chromosome condensation using a quantitative time-resolved fluorescence microscopy assay. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17005720	2006
A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell\| PubMed ID: 17174893	2006
Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin. The Journal of cell biology\| PubMed ID: 17339379	2007
A role for Rab5 in structuring the endoplasmic reticulum. The Journal of cell biology\| PubMed ID: 17591921	2007
MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation. PloS one\| PubMed ID: 17895996	2007
Cell division. WormBook : the online review of C. elegans biology\| PubMed ID: 18050484	2006
Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo. Methods in cell biology\| PubMed ID: 18155464	2008
SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules. The Journal of cell biology\| PubMed ID: 18299348	2008
A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex. Genes & development\| PubMed ID: 18765790	2008
Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches. Molecular biology of the cell\| PubMed ID: 19109417	2009
Structural memory in the contractile ring makes the duration of cytokinesis independent of cell size. Cell\| PubMed ID: 19490897	2009
The hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formation. Genes & development\| PubMed ID: 19656802	2009
Analyzing the effects of delaying aster separation on furrow formation during cytokinesis in the Caenorhabditis elegans embryo. Molecular biology of the cell\| PubMed ID: 19889842	2010
Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes & development\| PubMed ID: 20439434	2010
A kinetochore-independent mechanism drives anaphase chromosome separation during acentrosomal meiosis. Nature cell biology\| PubMed ID: 20729837	2010
The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. The Journal of cell biology\| PubMed ID: 21464231	2011
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell\| PubMed ID: 21529718	2011
Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest. PloS one\| PubMed ID: 21829677	2011
Acute drug treatment in the early C. elegans embryo. PloS one\| PubMed ID: 21935434	2011
Rapid de novo centromere formation occurs independently of heterochromatin protein 1 in C. elegans embryos. Current biology : CB\| PubMed ID: 22018540	2011
Affinity purification of protein complexes in C. elegans. Methods in cell biology\| PubMed ID: 22118282	2011
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. The Journal of cell biology\| PubMed ID: 22331849	2012
An inverse relationship to germline transcription defines centromeric chromatin in C. elegans. Nature\| PubMed ID: 22495302	2012
Cytokinesis in animal cells. Annual review of cell and developmental biology\| PubMed ID: 22804577	2012
Hierarchical assembly of the eggshell and permeability barrier in C. elegans. The Journal of cell biology\| PubMed ID: 22908315	2012
Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly. Developmental cell\| PubMed ID: 23673331	2013
A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis. Developmental cell\| PubMed ID: 24012485	2013
The midbody ring scaffolds the abscission machinery in the absence of midbody microtubules. The Journal of cell biology\| PubMed ID: 24217623	2013
Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation. Science (New York, N.Y.)\| PubMed ID: 24231804	2013
Meiotic double-strand breaks uncover and protect against mitotic errors in the C. elegans germline. Current biology : CB\| PubMed ID: 24239117	2013
Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes & development\| PubMed ID: 24449268	2014
A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint. The Journal of cell biology\| PubMed ID: 24567362	2014
Structure of the C. elegans ZYG-1 cryptic polo box suggests a conserved mechanism for centriolar docking of Plk4 kinases. Structure (London, England : 1993)\| PubMed ID: 24980795	2014
The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix. Molecular biology of the cell\| PubMed ID: 25103243	2014
The microtubule minus-end-binding protein patronin/PTRN-1 is required for axon regeneration in C. elegans. Cell reports\| PubMed ID: 25437544	2014
The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast. Current biology : CB\| PubMed ID: 25619765	2015
Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans. PloS one\| PubMed ID: 25919583	2015
Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science (New York, N.Y.)\| PubMed ID: 25931445	2015
Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro. Science (New York, N.Y.)\| PubMed ID: 25977552	2015
NOCA-1 functions with γ-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans. eLife\| PubMed ID: 26371552	2015
Non-centrosomal epidermal microtubules act in parallel to LET-502/ROCK to promote C. elegans elongation. Development (Cambridge, England)\| PubMed ID: 26586219	2016
A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions. Cell\| PubMed ID: 27020753	2016
53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. The Journal of cell biology\| PubMed ID: 27432897	2016
Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation. Biology open\| PubMed ID: 27591191	2016
A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly. Developmental cell\| PubMed ID: 27623381	2016
GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. Molecular biology of the cell\| PubMed ID: 27708138	2016
How centrioles acquire the ability to reproduce. eLife\| PubMed ID: 28271993	2017
Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex. Developmental cell\| PubMed ID: 28535376	2017
A toolkit for GFP-mediated tissue-specific protein degradation in . Development (Cambridge, England)\| PubMed ID: 28619826	2017
Kinetochores accelerate or delay APC/C activation by directing Cdc20 to opposing fates. Genes & development\| PubMed ID: 28698300	2017
TPXL-1 activates Aurora A to clear contractile ring components from the polar cortex during cytokinesis. The Journal of cell biology\| PubMed ID: 29311228	2018
Employing the one-cell C. elegans embryo to study cell division processes. Methods in cell biology\| PubMed ID: 29804670	2018
A positive-feedback-based mechanism for constriction rate acceleration during cytokinesis in . eLife\| PubMed ID: 29963981	2018
CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia. eLife\| PubMed ID: 29989548	2018
CFI-400945 is not a selective cellular PLK4 inhibitor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30377272	2018
The ARP2/3 complex prevents excessive formin activity during cytokinesis. Molecular biology of the cell\| PubMed ID: 30403552	2019
The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis. Developmental cell\| PubMed ID: 30827898	2019
Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity. Current biology : CB\| PubMed ID: 31495582	2019
Ancestral roles of the Fam20C family of secreted protein kinases revealed in . The Journal of cell biology\| PubMed ID: 31541016	2019
The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C. Developmental cell\| PubMed ID: 31588029	2019