Keizo Takao

Frontier Technology Center, Graduate School of Medicine, Kyoto University

Affiliated withGraduate School of Medicine, Kyoto University Fujita Health University National Institutes of Natural Sciences

Research Area

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JoVE Journal Publications

ArticleTotal : 4	Year
Publication title Cited by 267	2006
Publication title Cited by 551	2008
Publication title Cited by 92	2012
Publication title Cited by 149	2014

Other Publications

Article	Year
Ionic basis of cold receptors acting as thermostats. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12019319	2002
Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15788767	2005
Targeting quantum dots to surface proteins in living cells with biotin ligase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15897449	2005
Investigating gene-to-behavior pathways in psychiatric disorders: the use of a comprehensive behavioral test battery on genetically engineered mice. Annals of the New York Academy of Sciences\| PubMed ID: 17185513	2006
Impact of brain-behavior phenotypying of genetically-engineered mice on research of neuropsychiatric disorders. Neuroscience research\| PubMed ID: 17524507	2007
Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes. The European journal of neuroscience\| PubMed ID: 17880385	2007
[Investigating genes-to-behavior pathways in psychiatric diseases: an approach using a comprehensive behavioral test battery on genetically engineered mice]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology\| PubMed ID: 18646600	2008
Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia. Human molecular genetics\| PubMed ID: 18658164	2008
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nature neuroscience\| PubMed ID: 18758458	2008
Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Molecular brain\| PubMed ID: 18803808	2008
Comprehensive behavioral phenotyping of calpastatin-knockout mice. Molecular brain\| PubMed ID: 18803809	2008
Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia. Molecular brain\| PubMed ID: 18945333	2008
Mice lacking the kf-1 gene exhibit increased anxiety- but not despair-like behavior. Frontiers in behavioral neuroscience\| PubMed ID: 18958194	2008
Normal mitochondrial respiratory function is essential for spatial remote memory in mice. Molecular brain\| PubMed ID: 19087269	2008
Comprehensive behavioral phenotyping of ryanodine receptor type 3 (RyR3) knockout mice: decreased social contact duration in two social interaction tests. Frontiers in behavioral neuroscience\| PubMed ID: 19503748	2009
Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice. Molecular brain\| PubMed ID: 19538708	2009
Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism. Cell\| PubMed ID: 19563756	2009
Mice with altered myelin proteolipid protein gene expression display cognitive deficits accompanied by abnormal neuron-glia interactions and decreased conduction velocities. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19571127	2009
Intrauterine environment-genome interaction and children's development (4): Brain-behavior phenotypying of genetically-engineered mice using a comprehensive behavioral test battery on resear... The Journal of toxicological sciences\| PubMed ID: 19571483	2009
Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly. Nature medicine\| PubMed ID: 19734909	2009
Neural activity changes underlying the working memory deficit in alpha-CaMKII heterozygous knockout mice. Frontiers in behavioral neuroscience\| PubMed ID: 19750198	2009
KF-1 Ubiquitin Ligase: An Anxiety Suppressor. Frontiers in neuroscience\| PubMed ID: 19753093	2009
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Molecular brain\| PubMed ID: 19925672	2009
Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system. Nature neuroscience\| PubMed ID: 19935654	2009
SDOP-DB: a comparative standardized-protocol database for mouse phenotypic analyses. Bioinformatics (Oxford, England)\| PubMed ID: 20194625	2010
Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice. PloS one\| PubMed ID: 20209163	2010
[Immature dentate gyrus as a candidate endophenotype of psychiatric disorders]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology\| PubMed ID: 20666142	2010
Behavioral profiles of three C57BL/6 substrains. Frontiers in behavioral neuroscience\| PubMed ID: 20676234	2010
Stress-evoked tyrosine phosphorylation of signal regulatory protein Î± regulates behavioral immobility in the forced swim test. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20685990	2010
Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus. Molecular brain\| PubMed ID: 20815922	2010
Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors. Molecular and cellular neurosciences\| PubMed ID: 20851768	2011
[Genes, behaviors and psychiatric disorders]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme\| PubMed ID: 21089339	2008
Decreased exploratory activity in a mouse model of 15q duplication syndrome; implications for disturbance of serotonin signaling. PloS one\| PubMed ID: 21179543	2010
The influence of chronic cerebral hypoperfusion on cognitive function and amyloid Î² metabolism in APP overexpressing mice. PloS one\| PubMed ID: 21305033	2011
Synaptic E3 ligase SCRAPPER in contextual fear conditioning: extensive behavioral phenotyping of Scrapper heterozygote and overexpressing mutant mice. PloS one\| PubMed ID: 21390313	2011
Forebrain-specific constitutively active CaMKKÎ± transgenic mice show deficits in hippocampus-dependent long-term memory. Neurobiology of learning and memory\| PubMed ID: 21558011	2011
P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating. PloS one\| PubMed ID: 21698260	2011
Relaxin-3-deficient mice showed slight alteration in anxiety-related behavior. Frontiers in behavioral neuroscience\| PubMed ID: 21887138	2011
DIP/WISH deficiency enhances synaptic function and performance in the Barnes maze. Molecular brain\| PubMed ID: 22018352	2011
DRPLA transgenic mouse substrains carrying single copy of full-length mutant human DRPLA gene with variable sizes of expanded CAG repeats exhibit CAG repeat length- and age-dependent changes... Neurobiology of disease\| PubMed ID: 22342974	2012
Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits. Frontiers in behavioral neuroscience\| PubMed ID: 22347851	2011
Increased astrocytic ATP release results in enhanced excitability of the hippocampus. Glia\| PubMed ID: 23018918	2013
Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice. Frontiers in behavioral neuroscience\| PubMed ID: 23060763	2012
Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficien... Molecular brain\| PubMed ID: 23268962	2012
Behavioral abnormalities observed in Zfhx2-deficient mice. PloS one\| PubMed ID: 23300874	2012
Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 23389689	2013
Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly. Scientific reports\| PubMed ID: 23390575	2013
Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice. Molecular brain\| PubMed ID: 23497716	2013
ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response. BMC research notes\| PubMed ID: 23688147	2013
Immature dentate gyrus: an endophenotype of neuropsychiatric disorders. Neural plasticity\| PubMed ID: 23840971	2013
Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice. Molecular brain\| PubMed ID: 23938054	2013
Point mutation in syntaxin-1A causes abnormal vesicle recycling, behaviors, and short term plasticity. The Journal of biological chemistry\| PubMed ID: 24136198	2013
PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders. PloS one\| PubMed ID: 24312498	2013
Mice lacking collapsin response mediator protein 1 manifest hyperactivity, impaired learning and memory, and impaired prepulse inhibition. Frontiers in behavioral neuroscience\| PubMed ID: 24409129	2013
Absence of BRINP1 in mice causes increase of hippocampal neurogenesis and behavioral alterations relevant to human psychiatric disorders. Molecular brain\| PubMed ID: 24528488	2014
Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice. PloS one\| PubMed ID: 24586890	2014
Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia. Molecular brain\| PubMed ID: 24678719	2014
Comprehensive behavioral study of mGluR3 knockout mice: implication in schizophrenia related endophenotypes. Molecular brain\| PubMed ID: 24758191	2014
Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia. Molecular brain\| PubMed ID: 24886351	2014
Enhanced stability of hippocampal place representation caused by reduced magnesium block of NMDA receptors in the dentate gyrus. Molecular brain\| PubMed ID: 24893573	2014
Mechanisms for interferon-α-induced depression and neural stem cell dysfunction. Stem cell reports\| PubMed ID: 25068123	2014
[Immaturity of brain as an endophenotype of neuropsychiatric disorders]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology\| PubMed ID: 25076776	2014
Genomic responses in mouse models greatly mimic human inflammatory diseases. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25092317	2015
SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system. Molecular brain\| PubMed ID: 25167838	2014
IL1RAPL1 knockout mice show spine density decrease, learning deficiency, hyperactivity and reduced anxiety-like behaviours. Scientific reports\| PubMed ID: 25312502	2014
Reply to Warren et al. and Shay et al.: Commonalities across species do exist and are potentially important. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25540421	2015