Kelly M. McNagny The Biomedical Research Centre University of British Columbia Biography Publications Institution JoVE Articles Kelly M. McNagny has not added a biography. If you are Kelly M. McNagny and would like to personalize this page please email our Author Liaison for assistance. Publications HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression IScience. Mar, 2019 | Pubmed ID: 30818224 Podocalyxin is Required for Maintaining Blood-brain Barrier Function During Acute Inflammation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2019 | Pubmed ID: 30787191 The First Identified Heterozygous Nonsense Mutations in Podocalyxin Offer New Perspectives on the Biology of Podocytopathies Clinical Science (London, England : 1979). Feb, 2019 | Pubmed ID: 30737302 IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission During Chronic Infection Journal of Immunology (Baltimore, Md. : 1950). Feb, 2019 | Pubmed ID: 30617224 Mast Cells Promote Small Bowel Cancer in a Tumor Stage-specific and Cytokine-dependent Manner Proceedings of the National Academy of Sciences of the United States of America. 02, 2018 | Pubmed ID: 29429965 The Sialidase (Kdnase) Contributes to Cell Wall Integrity and Virulence in Amphotericin B-Treated Mice Frontiers in Microbiology. Month, 2017 | Pubmed ID: 29403452 Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development Stem Cells (Dayton, Ohio). 12, 2017 | Pubmed ID: 28905451 Loss of Vascular CD34 Results in Increased Sensitivity to Lung Injury American Journal of Respiratory Cell and Molecular Biology. 12, 2017 | Pubmed ID: 28683207 Induces a Type IV Hypersensitivity Response in a Mouse Model of Airway Inflammation Physiological Reports. Apr, 2017 | Pubmed ID: 28364028 Protein Interaction Screening Identifies SH3RF1 As a New Regulator of FAT1 Protein Levels FEBS Letters. Feb, 2017 | Pubmed ID: 28129444 The Orphan Nuclear Receptor RORα and Group 3 Innate Lymphoid Cells Drive Fibrosis in a Mouse Model of Crohn's Disease Science Immunology. Sep, 2016 | Pubmed ID: 28783681 The Orphan Nuclear Receptor ROR Alpha and Group 3 Innate Lymphoid Cells Drive Fibrosis in a Mouse Model of Crohn's Disease Science Immunology. Sep, 2016 | Pubmed ID: 28670633 Chronic Trichuris Muris Infection Alters Hematopoiesis and Causes IFN-γ-expressing T-cell Accumulation in the Mouse Bone Marrow European Journal of Immunology. 11, 2016 | Pubmed ID: 27594558 CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy PloS One. Month, 2016 | Pubmed ID: 27352134 G9a Regulates Group 2 Innate Lymphoid Cell Development by Repressing the Group 3 Innate Lymphoid Cell Program The Journal of Experimental Medicine. 06, 2016 | Pubmed ID: 27298444 SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling Developmental Cell. Apr, 2016 | Pubmed ID: 27046831 DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis PloS One. Month, 2016 | Pubmed ID: 27031833 Impact of a CXCL12/CXCR4 Antagonist in Bleomycin (BLM) Induced Pulmonary Fibrosis and Carbon Tetrachloride (CCl4) Induced Hepatic Fibrosis in Mice PloS One. Month, 2016 | Pubmed ID: 26998906 The Cell Surface Mucin Podocalyxin Regulates Collective Breast Tumor Budding Breast Cancer Research : BCR. Jan, 2016 | Pubmed ID: 26796961 Morphometric Analysis of Inflammation in Bronchial Biopsies Following Exposure to Inhaled Diesel Exhaust and Allergen Challenge in Atopic Subjects Particle and Fibre Toxicology. Jan, 2016 | Pubmed ID: 26758251 Dendritic-cell Expression of Ship1 Regulates Th2 Immunity to Helminth Infection in Mice European Journal of Immunology. Jan, 2016 | Pubmed ID: 26518471 Modelling Kidney Disease with CRISPR-mutant Kidney Organoids Derived from Human Pluripotent Epiblast Spheroids Nature Communications. Oct, 2015 | Pubmed ID: 26493500 Early Infancy Microbial and Metabolic Alterations Affect Risk of Childhood Asthma Science Translational Medicine. Sep, 2015 | Pubmed ID: 26424567 Podocalyxin Enhances Breast Tumor Growth and Metastasis and is a Target for Monoclonal Antibody Therapy Breast Cancer Research : BCR. Mar, 2015 | Pubmed ID: 25887862 Lineage-specific Regulation of Allergic Airway Inflammation by the Lipid Phosphatase Src Homology 2 Domain-containing Inositol 5-phosphatase (SHIP-1) The Journal of Allergy and Clinical Immunology. Sep, 2015 | Pubmed ID: 25746967 Pulmonary CD103 Expression Regulates Airway Inflammation in Asthma American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2015 | Pubmed ID: 25681437 Mast Cells in Human Health and Disease Methods in Molecular Biology (Clifton, N.J.). Month, 2015 | Pubmed ID: 25388247 Perinatal Antibiotic-induced Shifts in Gut Microbiota Have Differential Effects on Inflammatory Lung Diseases The Journal of Allergy and Clinical Immunology. Jan, 2015 | Pubmed ID: 25145536 Podocalyxin Regulates Murine Lung Vascular Permeability by Altering Endothelial Cell Adhesion PloS One. Month, 2014 | Pubmed ID: 25303643 Perinatal Immunization With Vaccine-Grade Listeria Monocytogenes Provides Protection Against Murine Th2 Airway Inflammation Allergy, Asthma & Immunology Research. Jul, 2014 | Pubmed ID: 24991458 Group 2 Innate Lymphoid Cells Facilitate Sensitization to Local, but Not Systemic, TH2-inducing Allergen Exposures The Journal of Allergy and Clinical Immunology. Apr, 2014 | Pubmed ID: 24679471 Methyltransferase G9A Regulates T Cell Differentiation During Murine Intestinal Inflammation The Journal of Clinical Investigation. May, 2014 | Pubmed ID: 24667637 Group 2 Innate Lymphoid Cells Are Critical for the Initiation of Adaptive T Helper 2 Cell-mediated Allergic Lung Inflammation Immunity. Mar, 2014 | Pubmed ID: 24613091 Enu Mutagenesis Identifies a Novel Platelet Phenotype in a Loss-of-function Jak2 Allele PloS One. Month, 2013 | Pubmed ID: 24086539 SIGIRR, a Negative Regulator of TLR/IL-1R Signalling Promotes Microbiota Dependent Resistance to Colonization by Enteric Bacterial Pathogens PLoS Pathogens. Month, 2013 | Pubmed ID: 23950714 Requirement for Core 2 O-glycans for Optimal Resistance to Helminth Infection PloS One. Month, 2013 | Pubmed ID: 23555902 A Familiar Stranger: CD34 Expression and Putative Functions in SVF Cells of Adipose Tissue World Journal of Stem Cells. Jan, 2013 | Pubmed ID: 23362435 Perinatal Antibiotic Treatment Affects Murine Microbiota, Immune Responses and Allergic Asthma Gut Microbes. Mar-Apr, 2013 | Pubmed ID: 23333861 IL-7Rα and L-selectin, but Not CD103 or CD34, Are Required for Murine Peanut-induced Anaphylaxis Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. Aug, 2012 | Pubmed ID: 22935073 Early Life Antibiotic-driven Changes in Microbiota Enhance Susceptibility to Allergic Asthma EMBO Reports. May, 2012 | Pubmed ID: 22422004 The Anti-adhesive Mucin Podocalyxin May Help Initiate the Transperitoneal Metastasis of High Grade Serous Ovarian Carcinoma Clinical & Experimental Metastasis. Mar, 2012 | Pubmed ID: 22262060 Analysis of the Mobilities of Band 3 Populations Associated with Ankyrin Protein and Junctional Complexes in Intact Murine Erythrocytes The Journal of Biological Chemistry. Feb, 2012 | Pubmed ID: 22147703 Cytopenia Induction by 5-fluorouracil Identifies Thrombopoietic Mutants in Sensitized ENU Mutagenesis Screens Experimental Hematology. Jan, 2012 | Pubmed ID: 21924221 CD34 Promotes Satellite Cell Motility and Entry into Proliferation to Facilitate Efficient Skeletal Muscle Regeneration Stem Cells (Dayton, Ohio). Dec, 2011 | Pubmed ID: 21997891 Infiltrating Monocytes Trigger EAE Progression, but Do Not Contribute to the Resident Microglia Pool Nature Neuroscience. Sep, 2011 | Pubmed ID: 21804537 CD34 is Required for Dendritic Cell Trafficking and Pathology in Murine Hypersensitivity Pneumonitis American Journal of Respiratory and Critical Care Medicine. Sep, 2011 | Pubmed ID: 21642249 Opposing Roles for CD34 in B16 Melanoma Tumor Growth Alter Early Stage Vasculature and Late Stage Immune Cell Infiltration PloS One. Apr, 2011 | Pubmed ID: 21494591 A Novel ENU-generated Truncation Mutation Lacking the Spectrin-binding and C-terminal Regulatory Domains of Ank1 Models Severe Hemolytic Hereditary Spherocytosis Experimental Hematology. Mar, 2011 | Pubmed ID: 21193012 CD34 is Required for Infiltration of Eosinophils into the Colon and Pathology Associated with DSS-induced Ulcerative Colitis The American Journal of Pathology. Sep, 2010 | Pubmed ID: 20696776 Interleukin-11 Reduces TLR4-induced Colitis in TLR2-deficient Mice and Restores Intestinal STAT3 Signaling Gastroenterology. Oct, 2010 | Pubmed ID: 20600022 CD34 Mediates Intestinal Inflammation in Salmonella-infected Mice Cellular Microbiology. Nov, 2010 | Pubmed ID: 20497179 The Metalloprotease-disintegrin ADAM8 is Essential for the Development of Experimental Asthma American Journal of Respiratory and Critical Care Medicine. Jun, 2010 | Pubmed ID: 20194813 Loss of CD34 Leads to Exacerbated Autoimmune Arthritis Through Increased Vascular Permeability Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010 | Pubmed ID: 20038636 Stem Cells, Inflammation and Allergy Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology. Dec, 2009 | Pubmed ID: 20066174 Prion Protein Expression and Release by Mast Cells After Activation The Journal of Infectious Diseases. Sep, 2009 | Pubmed ID: 19642931 SHIP1 is a Repressor of Mast Cell Hyperplasia, Cytokine Production, and Allergic Inflammation in Vivo Journal of Immunology (Baltimore, Md. : 1950). Jul, 2009 | Pubmed ID: 19542434 Bone Marrow-derived Mast Cells Accumulate in the Central Nervous System During Inflammation but Are Dispensable for Experimental Autoimmune Encephalomyelitis Pathogenesis Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19380799 Mast Cells in Tumor Growth: Angiogenesis, Tissue Remodelling and Immune-modulation Biochimica Et Biophysica Acta. Aug, 2009 | Pubmed ID: 19233249 Podocalyxin Selectively Marks Erythroid-committed Progenitors During Anemic Stress but is Dispensable for Efficient Recovery Experimental Hematology. Jan, 2009 | Pubmed ID: 19004540 Mast Cells Are an Essential Hematopoietic Component for Polyp Development Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18077429 CD34 Facilitates the Development of Allergic Asthma Blood. Sep, 2007 | Pubmed ID: 17557898 The CD34-related Molecule Podocalyxin is a Potent Inducer of Microvillus Formation PloS One. Feb, 2007 | Pubmed ID: 17311105 Na+/H+ Exchanger Regulatory Factor-1 is a Hematopoietic Ligand for a Subset of the CD34 Family of Stem Cell Surface Proteins Stem Cells (Dayton, Ohio). May, 2006 | Pubmed ID: 16410385 Hematopoietic Stem Cells Do Not Engraft with Absolute Efficiencies Blood. Jan, 2006 | Pubmed ID: 16204316 Podocalyxin is a CD34-related Marker of Murine Hematopoietic Stem Cells and Embryonic Erythroid Cells Blood. Jun, 2005 | Pubmed ID: 15701716 CD34 and CD43 Inhibit Mast Cell Adhesion and Are Required for Optimal Mast Cell Reconstitution Immunity. Jan, 2005 | Pubmed ID: 15664158 Overexpression of the Anti-adhesin Podocalyxin is an Independent Predictor of Breast Cancer Progression Cancer Research. Aug, 2004 | Pubmed ID: 15289306 E26 Leukemia Virus Converts Primitive Erythroid Cells into Cycling Multilineage Progenitors Blood. Feb, 2003 | Pubmed ID: 12393697 CD34 is a Specific Marker of Mature Murine Mast Cells Experimental Hematology. Oct, 2002 | Pubmed ID: 12384153 Avian Models to Study the Transcriptional Control of Hematopoietic Lineage Commitment and to Identify Lineage-specific Genes Cells, Tissues, Organs. Month, 2002 | Pubmed ID: 12021491 Anuria, Omphalocele, and Perinatal Lethality in Mice Lacking the CD34-related Protein Podocalyxin The Journal of Experimental Medicine. Jul, 2001 | Pubmed ID: 11435469 Chronische salmonella infectie veroorzaakte intestinale fibrose Bernard C. Lo1, Samuel B. Shin1, Melina Messing1, Kelly M. McNagny1 1The Biomedical Research Centre, University of British Columbia JoVE 60068 Immunology and Infection
Chronische salmonella infectie veroorzaakte intestinale fibrose Bernard C. Lo1, Samuel B. Shin1, Melina Messing1, Kelly M. McNagny1 1The Biomedical Research Centre, University of British Columbia JoVE 60068 Immunology and Infection