Lauren H. Sansing

Department of Neurology, University of Connecticut Health Center

Affiliated withUniversity of Connecticut Health Center School of Medicine, University of Pennsylvania Hartford Hospital

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 26	2011
Publication title	2025

Other Publications

Article	Year
Edema after intracerebral hemorrhage: correlations with coagulation parameters and treatment. Journal of neurosurgery\| PubMed ID: 12744358	2003
Willisian collateralization. Neurology\| PubMed ID: 15277632	2004
To close or not to close: PFO, sex and cerebrovascular events. The Journal of invasive cardiology\| PubMed ID: 17197717	2006
Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Annals of neurology\| PubMed ID: 17262855	2007
A patient with encephalitis associated with NMDA receptor antibodies. Nature clinical practice. Neurology\| PubMed ID: 17479076	2007
Obstructive hydrocephalus from venous sinus thrombosis. Neurocritical care\| PubMed ID: 18542853	2009
Prophylactic antiepileptic drug use is associated with poor outcome following ICH. Neurocritical care\| PubMed ID: 19319701	2009
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation. Nucleic acids research\| PubMed ID: 20457754	2010
Intracranial vertebrobasilar artery dissection associated with postpartum angiopathy. Stroke research and treatment\| PubMed ID: 20700423	2010
Noninflammatory Cerebral Vasculopathy Associated with Recurrent Ischemic Strokes. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 21075007	2010
Neutrophil depletion diminishes monocyte infiltration and improves functional outcome after experimental intracerebral hemorrhage. Acta neurochirurgica. Supplement\| PubMed ID: 21725751	2011
Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage. Annals of neurology\| PubMed ID: 22028224	2011
CX3CR1 signaling on monocytes is dispensable after intracerebral hemorrhage. PloS one\| PubMed ID: 25469644	2014
Effect of β-Adrenergic Antagonists on In-Hospital Mortality after Ischemic Stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 26163891	2015
Treatment of Edema Associated With Intracerebral Hemorrhage. Current treatment options in neurology\| PubMed ID: 26874842	2016
Stroke as the Initial Manifestation of the Human Immunodeficiency Virus. Stroke\| PubMed ID: 26941257	2016
Intracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-Analysis. Neurocritical care\| PubMed ID: 27160888	2016
Intracerebral Hemorrhage. Seminars in neurology\| PubMed ID: 27214696	2016
TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage. The Journal of clinical investigation\| PubMed ID: 27893460	2017
Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injury. Neurocritical care\| PubMed ID: 28685394	2017
Erythrocyte efferocytosis modulates macrophages towards recovery after intracerebral hemorrhage. The Journal of clinical investigation\| PubMed ID: 29251628	2018
CCL2 and CXCL10 are associated with poor outcome after intracerebral hemorrhage. Annals of clinical and translational neurology\| PubMed ID: 30128320	2018
Serum Markers of Blood-Brain Barrier Remodeling and Fibrosis as Predictors of Etiology and Clinicoradiologic Outcome in Intracerebral Hemorrhage. Frontiers in neurology\| PubMed ID: 30258397	2018
Cardioembolic Stroke Risk and Recovery After Anticoagulation-Related Intracerebral Hemorrhage. Stroke\| PubMed ID: 30355194	2018
Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke. Cell\| PubMed ID: 31056284	2019
Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional Outcome. Stroke\| PubMed ID: 31159701	2019
Transforming growth factor-β promotes basement membrane fibrosis, alters perivascular cerebrospinal fluid distribution, and worsens neurological recovery in the aged brain after stroke. GeroScience\| PubMed ID: 31721012	2019
Perihematomal Edema After Intracerebral Hemorrhage in Patients With Active Malignancy. Stroke\| PubMed ID: 31744426	2020
Bexarotene Enhances Macrophage Erythrophagocytosis and Hematoma Clearance in Experimental Intracerebral Hemorrhage. Stroke\| PubMed ID: 31826730	2020
Antiplatelet Therapy After Spontaneous Intracerebral Hemorrhage and Functional Outcomes. Stroke\| PubMed ID: 31895618	2019
Fixed Compared With Autoregulation-Oriented Blood Pressure Thresholds After Mechanical Thrombectomy for Ischemic Stroke. Stroke\| PubMed ID: 32078493	2020
Response by Chang and Sansing to Letter Regarding Article, "Bexarotene Enhances Macrophage Erythrophagocytosis and Hematoma Clearance in Experimental Intracerebral Hemorrhage". Stroke\| PubMed ID: 32299318	2020
Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic. Stroke\| PubMed ID: 32755347	2020
Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke. Stroke\| PubMed ID: 32781941	2020
Direct carotid puncture for mechanical thrombectomy in acute ischemic stroke patients with prohibitive vascular access. Journal of neurosurgery\| PubMed ID: 32796146	2021
Plasma neurofilament light predicts mortality in patients with stroke. Science translational medicine\| PubMed ID: 33177179	2020
New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases. Frontiers in aging neuroscience\| PubMed ID: 33584250	2021
Association of Serum IL-6 (Interleukin 6) With Functional Outcome After Intracerebral Hemorrhage. Stroke\| PubMed ID: 33682454	2021
Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu. JCI insight\| PubMed ID: 33749664	2021
Obstructive Sleep Apnea as a Risk Factor for Intracerebral Hemorrhage. Stroke\| PubMed ID: 33827242	2021
Endothelial cell secreted VEGF-C enhances NSC VEGFR3 expression and promotes NSC survival. Stem cell research\| PubMed ID: 33836422	2021
Divergent Functions of Tissue-Resident and Blood-Derived Macrophages in the Hemorrhagic Brain. Stroke\| PubMed ID: 33840225	2021
Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage. Science immunology\| PubMed ID: 33891558	2021
Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients. Stroke\| PubMed ID: 33966492	2021
Admission computed tomography radiomic signatures outperform hematoma volume in predicting baseline clinical severity and functional outcome in the ATACH-2 trial intracerebral hemorrhage pop... European journal of neurology\| PubMed ID: 34189814	2021
Early Inflammatory Cytokine Expression in Cerebrospinal Fluid of Patients with Spontaneous Intraventricular Hemorrhage. Biomolecules\| PubMed ID: 34439789	2021
Exogenous inter-α inhibitor proteins prevent cell death and improve ischemic stroke outcomes in mice. The Journal of clinical investigation\| PubMed ID: 34580244	2021
Prior Stroke and Age Predict Acute Ischemic Stroke Among Hospitalized COVID-19 Patients: A Derivation and Validation Study. Frontiers in neurology\| PubMed ID: 34675873	2021
International Post Stroke Epilepsy Research Consortium (IPSERC): A consortium to accelerate discoveries in preventing epileptogenesis after stroke. Epilepsy & behavior : E&B\| PubMed ID: 34968775	2022
The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results. Stroke\| PubMed ID: 35354299	2022
Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions. Circulation research\| PubMed ID: 35420918	2022
CT angiographic radiomics signature for risk stratification in anterior large vessel occlusion stroke. NeuroImage. Clinical\| PubMed ID: 35550243	2022
Inflammatory Responses After Ischemic Stroke. Seminars in immunopathology\| PubMed ID: 35767089	2022
Dataset on acute stroke risk stratification from CT angiographic radiomics. Data in brief\| PubMed ID: 36060820	2022
Neuroimmune interactions in health and disease. Seminars in immunopathology\| PubMed ID: 36171280	2022
Baseline Serum Biomarkers of Inflammation and Subsequent Visit-to-Visit Blood Pressure Variability: A Post Hoc Analysis of MESA. American journal of hypertension\| PubMed ID: 36315490	2023
Embracing Heterogeneity in The Multicenter Stroke Preclinical Assessment Network (SPAN) Trial. Stroke\| PubMed ID: 36601951	2023
Common Pathways of Epileptogenesis in Patients With Epilepsy Post-Brain Injury: Findings From a Systematic Review and Meta-analysis. Neurology\| PubMed ID: 37550071	2023
A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke. Science translational medicine\| PubMed ID: 37729432	2023
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage. Neurocritical care\| PubMed ID: 37919545	2024
Trained immunity induced by high-salt diet impedes stroke recovery. EMBO reports\| PubMed ID: 37965920	2023
VEGF-C prophylaxis favors lymphatic drainage and modulates neuroinflammation in a stroke model. The Journal of experimental medicine\| PubMed ID: 38442272	2024
Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PloS one\| PubMed ID: 38870240	2024
Biological and Procedural Predictors of Outcome in the Stroke Preclinical Assessment Network (SPAN) Trial. Circulation research\| PubMed ID: 39034919	2024
An Approach to Successful Development of Clinician-Scientists in Neurology: The NINDS R25 Experience. Annals of neurology\| PubMed ID: 39099460	2024
Deep learning for prediction of post-thrombectomy outcomes based on admission CT angiography in large vessel occlusion stroke. Frontiers in artificial intelligence\| PubMed ID: 39149161	2024
Stroke Controversies and Debates: Imaging in Intracerebral Hemorrhage. Stroke\| PubMed ID: 39355925	2024
Single-nucleus RNA sequencing of human periventricular white matter in vascular dementia. bioRxiv : the preprint server for biology\| PubMed ID: 39713290	2024
Single-Cell Analysis in Cerebrovascular Research: Primed for Breakthroughs and Clinical Impact. Stroke\| PubMed ID: 39772596	2025
Elevated initial blood kynurenine is associated with increased odds of post-stroke infection: Kynurenine and post-stroke infection. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association\| PubMed ID: 40015349	2025
Uric Acid Stroke Cerebroprotection Transcended Sex, Age, and Comorbidities in a Multicenter Preclinical Trial. Stroke\| PubMed ID: 40091742	2025
Intracerebral haemorrhage laterality and associations with mood and pain: a MISTIE III substudy. Stroke and vascular neurology\| PubMed ID: 40250866	2025
Determinants of Outcome After Endovascular Middle Cerebral Artery Occlusion in Rats in the SPAN Trial. Stroke\| PubMed ID: 40396268	2025
Multicenter SPAN Trial of Fasudil in Ischemic Stroke. Stroke\| PubMed ID: 40421536	2025
Fingolimod as a Potential Cerebroprotectant Results From the Stroke Preclinical Assessment Network. Stroke\| PubMed ID: 40899256	2025
Preclinical Ischemic Stroke Multicenter (PRISM) Trials Collective Statement: Opportunities, Challenges, and Recommendations for a New Era. Stroke\| PubMed ID: 40931817	2025
Clot Composition and Ischemic Stroke Etiology: A Contemporary Narrative Review. Journal of clinical medicine\| PubMed ID: 40943965	2025
Multicenter Stroke Preclinical Assessment Network Analysis of Cardiovascular Risk Factor Subgroups Treated With the Poly(ADP-Ribose) Polymerase Inhibitor Veliparib. Journal of the American Heart Association\| PubMed ID: 40996065	2025
Ryanodine receptor 2-mediated calcium leak is associated with increased glyoxalase I in the aging brain. JCI insight\| PubMed ID: 41100182	2025
Evaluating tocilizumab in ischemic stroke: Findings from the SPAN multicenter trial. Neuropharmacology\| PubMed ID: 41354124	2025