Le Kang Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences Fudan University Biography Publications Institution JoVE Articles Le Kang has not added a biography. If you are Le Kang and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Differential Expression Genes Between Volume and Pressure Overloaded Hearts Based on Bioinformatics Analysis Genes. Jul, 2022 | Pubmed ID: 35886059 Erratum: Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling: Erratum Theranostics. 2022 | Pubmed ID: 35547765 Preoperative and Intraoperative Risk Factors of Postoperative Stroke in Total Aortic Arch Replacement and Stent Elephant Trunk Implantation EClinicalMedicine. May, 2022 | Pubmed ID: 35518120 PiRNA-guided Intron Removal from Pre-mRNAs Regulates Density-dependent Reproductive Strategy Cell Reports. 04, 2022 | Pubmed ID: 35476998 Shotgun Lipidomics Combined Targeted MRM Reveals Sphingolipid Signatures of Coronary Artery Disease Talanta. Aug, 2022 | Pubmed ID: 35462138 Differential MRNA Expression and Circular RNA-Based Competitive Endogenous RNA Networks in the Three Stages of Heart Failure in Transverse Aortic Constriction Mice Frontiers in Physiology. 2022 | Pubmed ID: 35330931 Circulating Soluble Receptor of Advanced Glycation End Product is Associated with Bicuspid Aortic Aneurysm Progression Via NF-κB Pathway Interactive Cardiovascular and Thoracic Surgery. 01, 2022 | Pubmed ID: 34648622 Oxidized LDL but Not Angiotensin II Induces Cardiomyocyte Hypertrophic Responses Through the Interaction Between LOX-1 and AT Receptors Journal of Molecular and Cellular Cardiology. 01, 2022 | Pubmed ID: 34555408 Involvement of Endoplasmic Reticulum Stress-Mediated Activation of C/EBP Homologous Protein in Aortic Regurgitation-Induced Cardiac Remodeling in Mice Journal of Cardiovascular Translational Research. 04, 2022 | Pubmed ID: 34426929 Cardioprotective Effects of N-3 Polyunsaturated Fatty Acids: Orchestration of MRNA Expression, Protein Phosphorylation, and Lipid Metabolism in Pressure Overload Hearts Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 35047577 Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 34631840 Long-Term Outcomes of Surgical Treatment for Acute Type-A Aortic Dissection with Coronary Artery Involvement International Heart Journal. 2021 | Pubmed ID: 34588406 MicroRNAs Involve in Bicuspid Aortic Aneurysm: Pathogenesis and Biomarkers Journal of Cardiothoracic Surgery. Aug, 2021 | Pubmed ID: 34384454 On the Origin of SARS-CoV-2-The Blind Watchmaker Argument Science China. Life Sciences. 09, 2021 | Pubmed ID: 34269976 Identification of Differently Expressed MRNAs in Atherosclerosis Reveals CDK6 Is Regulated by CircHIPK3/miR-637 Axis and Promotes Cell Growth in Human Vascular Smooth Muscle Cells Frontiers in Genetics. 2021 | Pubmed ID: 33659023 Left Ventricular Response in the Transition from Hypertrophy to Failure Recapitulates Distinct Roles of Akt, β-arrestin-2, and CaMKII in Mice with Aortic Regurgitation Annals of Translational Medicine. Mar, 2020 | Pubmed ID: 32309366 An An Open-Label, Single Center, Retrospective Study to Evaluate Clinical Outcomes with Surgical Sealant in Bentall Procedures: A Cohort Study The Heart Surgery Forum. Sep, 2019 | Pubmed ID: 31596719 Mechanical Stresses Induce Paracrine β-2 Microglobulin from Cardiomyocytes to Activate Cardiac Fibroblasts Through Epidermal Growth Factor Receptor Clinical Science (London, England : 1979). 08, 2018 | Pubmed ID: 30072448 MicroRNA-378 Suppresses Myocardial Fibrosis Through a Paracrine Mechanism at the Early Stage of Cardiac Hypertrophy Following Mechanical Stress Theranostics. 2018 | Pubmed ID: 29721099 Cardiomyocyte-Restricted Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) Deletion Leads to Lethal Dilated Cardiomyopathy Partly Through Drp1 Signaling Theranostics. 2018 | Pubmed ID: 29344294 Advanced Glycation End Products Impair the Functions of Saphenous Vein but Not Thoracic Artery Smooth Muscle Cells Through RAGE/MAPK Signalling Pathway in Diabetes Journal of Cellular and Molecular Medicine. 10, 2016 | Pubmed ID: 27297874 The Effects of Different Angiotensin II Type 1 Receptor Blockers on the Regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas Axes in Pressure Overload-induced Cardiac Remodeling in Male Mice Journal of Molecular and Cellular Cardiology. 08, 2016 | Pubmed ID: 27210827 Aliskiren Ameliorates Pressure Overload-induced Heart Hypertrophy and Fibrosis in Mice Acta Pharmacologica Sinica. Aug, 2014 | Pubmed ID: 24998254 Surgically Induced Cardiac Volume Overload by Aortic Regurgitation in Mouse Jian Wu*1, Shijun Wang*1, Le Kang*1, Chunjie Yang*1, Jianguo Jia1, Xingxu Wang2, Ge Wei1, Xuan Li1, Jieyun You2, Yunzeng Zou1 1Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, 2Department of Cardiovascular Medicine, Shanghai East Hospital, School of Medicine, Tongji University JoVE 63579 Biology
Surgically Induced Cardiac Volume Overload by Aortic Regurgitation in Mouse Jian Wu*1, Shijun Wang*1, Le Kang*1, Chunjie Yang*1, Jianguo Jia1, Xingxu Wang2, Ge Wei1, Xuan Li1, Jieyun You2, Yunzeng Zou1 1Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, 2Department of Cardiovascular Medicine, Shanghai East Hospital, School of Medicine, Tongji University JoVE 63579 Biology
