Lorenz Aglas

Department of Biosciences, University of Salzburg

Research Area

Biography

Basic research aspects: My research activities focuses on understanding the mechanism of allergic sensitization induced by pollen allergens, the induction of immune tolerance, and the molecular/immunological characterization of allergens.

Translational research: Development of novel therapeutic approaches for the treatment of (pollen) allergies

Main Research Areas

Molecular Biology, Molecular and Cellular Allergology, Immunology

Allergy diagnosis and treatment

Recombinant molecules and physico-chemical characterization

Mimetic peptide characterization

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2021

Other Publications

Article	Year
Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S. International journal of molecular sciences\| PubMed ID: 29035299
Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity. The Journal of allergy and clinical immunology\| PubMed ID: 29157946
Context matters: T2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity. The Journal of allergy and clinical immunology\| PubMed ID: 29782896
Does clinical outcome of birch pollen immunotherapy relate to induction of blocking antibodies preventing IgE from allergen binding? A pilot study monitoring responses during first year of A... Clinical and translational allergy\| PubMed ID: 30338052
Effectiveness of Grounded Sleeping on Recovery After Intensive Eccentric Muscle Loading. Frontiers in physiology\| PubMed ID: 30745882
Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity. Allergy\| PubMed ID: 31230350
TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice. Allergy\| PubMed ID: 31750952
N-terminal peptide deletion influences immunological and structural features of Blo t 5. Allergy\| PubMed ID: 31916257
Defining biomarkers to predict symptoms in subjects with and without allergy under natural pollen exposure. The Journal of allergy and clinical immunology\| PubMed ID: 32272131
A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology\| PubMed ID: 32314444
Ligand Binding of PR-10 Proteins with a Particular Focus on the Bet v 1 Allergen Family. Current allergy and asthma reports\| PubMed ID: 32430735	2020
Initiating pollen sensitization - complex source, complex mechanisms. Clinical and translational allergy\| PubMed ID: 32884636	2020
Induction of Functional Inhibitory IgG Antibodies by a Hypoallergenic Bet v 1 Variant. Frontiers in immunology\| PubMed ID: 33013894	2020
Ragweed plants grown under elevated CO levels produce pollen which elicit stronger allergic lung inflammation. Allergy\| PubMed ID: 33037672	2021
Identification and Physicochemical Characterization of a New Allergen from . International journal of molecular sciences\| PubMed ID: 33371317	2020
IgE-cross-blocking antibodies to Fagales following sublingual immunotherapy with recombinant Bet v 1. Allergy\| PubMed ID: 33724487	2021

Article	Year
Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S. International journal of molecular sciences\| PubMed ID: 29035299
Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity. The Journal of allergy and clinical immunology\| PubMed ID: 29157946
Context matters: T2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity. The Journal of allergy and clinical immunology\| PubMed ID: 29782896
Does clinical outcome of birch pollen immunotherapy relate to induction of blocking antibodies preventing IgE from allergen binding? A pilot study monitoring responses during first year of A... Clinical and translational allergy\| PubMed ID: 30338052
Effectiveness of Grounded Sleeping on Recovery After Intensive Eccentric Muscle Loading. Frontiers in physiology\| PubMed ID: 30745882
Multiple roles of Bet v 1 ligands in allergen stabilization and modulation of endosomal protease activity. Allergy\| PubMed ID: 31230350
TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice. Allergy\| PubMed ID: 31750952
N-terminal peptide deletion influences immunological and structural features of Blo t 5. Allergy\| PubMed ID: 31916257
Defining biomarkers to predict symptoms in subjects with and without allergy under natural pollen exposure. The Journal of allergy and clinical immunology\| PubMed ID: 32272131
A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology\| PubMed ID: 32314444
Ligand Binding of PR-10 Proteins with a Particular Focus on the Bet v 1 Allergen Family. Current allergy and asthma reports\| PubMed ID: 32430735	2020
Initiating pollen sensitization - complex source, complex mechanisms. Clinical and translational allergy\| PubMed ID: 32884636	2020
Induction of Functional Inhibitory IgG Antibodies by a Hypoallergenic Bet v 1 Variant. Frontiers in immunology\| PubMed ID: 33013894	2020
Ragweed plants grown under elevated CO levels produce pollen which elicit stronger allergic lung inflammation. Allergy\| PubMed ID: 33037672	2021
Identification and Physicochemical Characterization of a New Allergen from . International journal of molecular sciences\| PubMed ID: 33371317	2020
IgE-cross-blocking antibodies to Fagales following sublingual immunotherapy with recombinant Bet v 1. Allergy\| PubMed ID: 33724487	2021