Lorenz Studer

Developmental Biology, Sloan-Kettering Institute for Cancer Research

Affiliated withSloan-Kettering Institute for Cancer Research Memorial Sloan-Kettering Cancer Center

Research Area

Biography

Lorenz Studer has not added Biography.
If you are Lorenz Studer and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 24	2014
Publication title Cited by 12	2016

Other Publications

Article	Year
Parthenogenetic stem cells in nonhuman primates. Science (New York, N.Y.)\| PubMed ID: 11823632	2002
Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research\| PubMed ID: 12114215	2002
Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression. Journal of neurochemistry\| PubMed ID: 12787064	2003
Neural transplantation for the treatment of Parkinson's disease. Lancet neurology\| PubMed ID: 12849125	2003
Making and repairing the mammalian brain--in vitro production of dopaminergic neurons. Seminars in cell & developmental biology\| PubMed ID: 12948353	2003
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nature biotechnology\| PubMed ID: 14502203	2003
Nonhuman primate parthenogenetic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14504386	2003
Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bc... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 14749429	2004
Derivation of midbrain dopamine neurons from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15310843	2004
Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells. Functional & integrative genomics\| PubMed ID: 15690164	2005
Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nature biotechnology\| PubMed ID: 15852001	2005
Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. Stem cells (Dayton, Ohio)\| PubMed ID: 15941857	2005
Derivation of multipotent mesenchymal precursors from human embryonic stem cells. PLoS medicine\| PubMed ID: 15971941	2005
Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library. Stem cells (Dayton, Ohio)\| PubMed ID: 16990587	2007
Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft. The European journal of neuroscience\| PubMed ID: 17067292	2006
Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17077287	2006
Embryonic stem cell-derived neurons form functional networks in vitro. Stem cells (Dayton, Ohio)\| PubMed ID: 17110621	2007
Constitutive gene expression predisposes morphogen-mediated cell fate responses of NT2/D1 and 27X-1 human embryonal carcinoma cells. Stem cells (Dayton, Ohio)\| PubMed ID: 17138961	2007
Mesenchymal cells. Methods in enzymology\| PubMed ID: 17141037	2006
Derivation of engraftable skeletal myoblasts from human embryonic stem cells. Nature medicine\| PubMed ID: 17417652	2007
Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons. Stem cells (Dayton, Ohio)\| PubMed ID: 17478583	2007
Optical bioluminescence imaging of human ES cell progeny in the rodent CNS. Journal of neurochemistry\| PubMed ID: 17555555	2007
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Nature biotechnology\| PubMed ID: 18037878	2007
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes & development\| PubMed ID: 18198334	2008
Therapeutic cloning in individual parkinsonian mice. Nature medicine\| PubMed ID: 18376409	2008
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell stem cell\| PubMed ID: 18522853	2008
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. Brain : a journal of neurology\| PubMed ID: 18669499	2008
BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage. Stem cells (Dayton, Ohio)\| PubMed ID: 19074416	2009
Too much Sonic, too few neurons. Nature neuroscience\| PubMed ID: 19172163	2009
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nature biotechnology\| PubMed ID: 19252484	2009
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes & development\| PubMed ID: 19270157	2009
Wnt1 overexpression leads to enforced cardiomyogenesis and inhibition of hematopoiesis in murine embryonic stem cells. Stem cells and development\| PubMed ID: 19422288	2010
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19549847	2009
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature\| PubMed ID: 19693009	2009
Protocols for generating ES cell-derived dopamine neurons. Advances in experimental medicine and biology\| PubMed ID: 19731555	2009
Induced pluripotent stem cell technology for the study of human disease. Nature methods\| PubMed ID: 20038952	2010
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nature biotechnology\| PubMed ID: 20081865	2010
Enriched motor neuron populations derived from bacterial artificial chromosome-transgenic human embryonic stem cells. Clinical neurosurgery\| PubMed ID: 20214043	2009
Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20357117	2010
Derivation of neural crest cells from human pluripotent stem cells. Nature protocols\| PubMed ID: 20360764	2010
Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell stem cell\| PubMed ID: 20362538	2010
Single-molecule analysis reveals changes in the DNA replication program for the POU5F1 locus upon human embryonic stem cell differentiation. Molecular and cellular biology\| PubMed ID: 20647538	2010
Neuroscience: Excessive mobility interrupted. Nature\| PubMed ID: 21085168	2010
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells. Nature biotechnology\| PubMed ID: 21151124	2011
Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling. Nature communications\| PubMed ID: 21245843	2011
IPSCs put to the test. Nature biotechnology\| PubMed ID: 21390027	2011
miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells. Cell stem cell\| PubMed ID: 21624813	2011
Cell fate plug and play: direct reprogramming and induced pluripotency. Cell\| PubMed ID: 21663788	2011
Modelling familial dysautonomia in human induced pluripotent stem cells. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 21727134	2011
Converting human pluripotent stem cells to neural tissue and neurons to model neurodegeneration. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21913095	2011
Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes & development\| PubMed ID: 22012620	2011
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature\| PubMed ID: 22056989	2011
Cellular reprogramming: recent advances in modeling neurological diseases. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22072658	2011
A poised chromatin platform for TGF-Î² access to master regulators. Cell\| PubMed ID: 22196728	2011
The expanding role of miR-302-367 in pluripotency and reprogramming. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22436490	2012
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells. Environmental health perspectives\| PubMed ID: 22571897	2012
Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nature biotechnology\| PubMed ID: 22750882	2012
Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. The Journal of clinical investigation\| PubMed ID: 22751106	2012
Maturation of spinal motor neurons derived from human embryonic stem cells. PloS one\| PubMed ID: 22802953	2012
ZFX controls the self-renewal of human embryonic stem cells. PloS one\| PubMed ID: 22879936	2012
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature\| PubMed ID: 23103873	2012
Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression. Nature biotechnology\| PubMed ID: 23159879	2012
Derivation of dopaminergic neurons from pluripotent stem cells. Progress in brain research\| PubMed ID: 23195422	2012
Adapting human pluripotent stem cells to high-throughput and high-content screening. Nature protocols\| PubMed ID: 23257981	2013
Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination. Cell stem cell\| PubMed ID: 23395447	2013
Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs. Cell reports\| PubMed ID: 23583175	2013
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell stem cell\| PubMed ID: 23642365	2013
Build-a-brain. Cell stem cell\| PubMed ID: 24094317	2013
Specification of functional cranial placode derivatives from human pluripotent stem cells. Cell reports\| PubMed ID: 24290755	2013
Dual-SMAD Inhibition/WNT Activation-Based Methods to Induce Neural Crest and Derivatives from Human Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 24301074	2013
Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice. Stem cells translational medicine\| PubMed ID: 24311700	2014
Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell stem cell\| PubMed ID: 24315443	2013
Pluripotent stem cells in regenerative medicine: challenges and recent progress. Nature reviews. Genetics\| PubMed ID: 24434846	2014
MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration. Nature communications\| PubMed ID: 24736453	2014
Aging in iPS cells. Aging\| PubMed ID: 24799443	2014
A cell engineering strategy to enhance the safety of stem cell therapies. Cell reports\| PubMed ID: 25242333	2014
Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson's disease model. Nature biotechnology\| PubMed ID: 25580598	2015
Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England)\| PubMed ID: 25670790	2015
The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells. Stem cell reports\| PubMed ID: 25754204	2015
Moving stem cells to the clinic: potential and limitations for brain repair. Neuron\| PubMed ID: 25856494	2015
Deciphering Human Cell-Autonomous Anti-HSV-1 Immunity in the Central Nervous System. Frontiers in immunology\| PubMed ID: 26005444	2015
Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency. Cell stem cell\| PubMed ID: 26046759	2015
Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PloS one\| PubMed ID: 26120834	2015
Retinoic Acid-Mediated Regulation of GLI3 Enables Efficient Motoneuron Derivation from Human ESCs in the Absence of Extrinsic SHH Activation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26290227	2015
Neural Crest Cells from Dual SMAD Inhibition. Current protocols in stem cell biology\| PubMed ID: 26344232	2015
When rejuvenation is a problem: challenges of modeling late-onset neurodegenerative disease. Development (Cambridge, England)\| PubMed ID: 26395137	2015
Functional Connectivity under Optogenetic Control Allows Modeling of Human Neuromuscular Disease. Cell stem cell\| PubMed ID: 26549107	2016
Back and forth in time: Directing age in iPSC-derived lineages. Brain research\| PubMed ID: 26592774	2015
Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem cell reports\| PubMed ID: 26610635	2015
Pluripotent stem cell-based disease modeling: current hurdles and future promise. Current opinion in cell biology\| PubMed ID: 26629748	2015
Correction: Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PloS one\| PubMed ID: 26799319	2016
α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 26839413	2016
Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature\| PubMed ID: 26863197	2016