Luis A. Herrera Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología-Instituto de Investigaciones Biomédicas Universidad Nacional Autónoma de México Biography Publications Institution JoVE Articles Luis A. Herrera has not added a biography. If you are Luis A. Herrera and would like to personalize this page please email our Author Liaison for assistance. Publications Deep DNA Sequencing of MGMT, TP53 and AGT in Mexican Astrocytoma Patients Identifies an Excess of Genetic Variants in Women and a Predictive Biomarker Journal of Neuro-oncology. Jan, 2023 | Pubmed ID: 36525166 LncRNAs-associated to Genomic Instability: A Barrier to Cancer Therapy Effectiveness Frontiers in Genetics. 2022 | Pubmed ID: 36479250 Histones and Their Chaperones: Adaptive Remodelers of an Ever-changing Chromatinic Landscape Frontiers in Genetics. 2022 | Pubmed ID: 36468032 Probability of Hospitalisation and Death Among COVID-19 Patients with Comorbidity During Outbreaks Occurring in Mexico City Journal of Global Health. Nov, 2022 | Pubmed ID: 36342697 Somatic Mutational Landscape in Mexican Patients: Mutations and Chr20q13.33 Amplifications Are Associated with Diffuse-Type Gastric Adenocarcinoma International Journal of Molecular Sciences. Sep, 2022 | Pubmed ID: 36232418 Transcriptomics and RNA-Based Therapeutics As Potential Approaches to Manage SARS-CoV-2 Infection International Journal of Molecular Sciences. Sep, 2022 | Pubmed ID: 36232363 DNA Methyltransferases: From Evolution to Clinical Applications International Journal of Molecular Sciences. Aug, 2022 | Pubmed ID: 36012258 The Roles of Histone Post-Translational Modifications in the Formation and Function of a Mitotic Chromosome International Journal of Molecular Sciences. Aug, 2022 | Pubmed ID: 35955838 An RBD-Based Diagnostic Method Useful for the Surveillance of Protective Immunity Against SARS-CoV-2 in the Population Diagnostics (Basel, Switzerland). Jul, 2022 | Pubmed ID: 35885534 Analytical Performances of the COVISTIX Antigen Rapid Test for SARS-CoV-2 Detection in an Unselected Population (All-Comers) Pathogens (Basel, Switzerland). May, 2022 | Pubmed ID: 35745482 Insights of Oncofertility in Mexico and Latin America Frontiers in Oncology. 2022 | Pubmed ID: 35600375 Early Genomic, Epidemiological, and Clinical Description of the SARS-CoV-2 Omicron Variant in Mexico City Viruses. Mar, 2022 | Pubmed ID: 35336952 Methylation of Subtelomeric Chromatin Modifies the Expression of the LncRNA TERRA, Disturbing Telomere Homeostasis International Journal of Molecular Sciences. Mar, 2022 | Pubmed ID: 35328692 Large-scale Topological Disruption of Chromosome Territories 9 and 22 is Associated with Nonresponse to Treatment in CML International Journal of Cancer. May, 2022 | Pubmed ID: 34913480 Proteasome Inhibition Alters Mitotic Progression Through the Upregulation of Centromeric α-Satellite RNAs The FEBS Journal. Apr, 2022 | Pubmed ID: 34739170 Mitotic and DNA Damage Response Proteins: Maintaining the Genome Stability and Working for the Common Good Frontiers in Cell and Developmental Biology. 2021 | Pubmed ID: 34966733 Transcriptome Analysis Identifies GATA3-AS1 As a Long Noncoding RNA Associated with Resistance to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Patients The Journal of Molecular Diagnostics : JMD. Oct, 2021 | Pubmed ID: 34358678 Analysis of the CAG Tract Length in the Androgen Receptor Gene in Mexican Patients with Nonsyndromic Cryptorchidism Journal of Pediatric Endocrinology & Metabolism : JPEM. Jul, 2021 | Pubmed ID: 33838085 Saliva is a Reliable and Accessible Source for the Detection of SARS-CoV-2 International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Apr, 2021 | Pubmed ID: 33581365 Indolaminergic System in Adult Rat Testes: Evidence for a Local Serotonin System Frontiers in Neuroanatomy. 2020 | Pubmed ID: 33679336 Epidrug Repurposing: Discovering New Faces of Old Acquaintances in Cancer Therapy Frontiers in Oncology. 2020 | Pubmed ID: 33312959 Prognostic Significance of the MAD1L1 1673 G: A Polymorphism in Ovarian Adenocarcinomas Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion. Dec, 2020 | Pubmed ID: 33052898 Molecular Alterations Prompted by SARS-CoV-2 Infection: Induction of Hyaluronan, Glycosaminoglycan and Mucopolysaccharide Metabolism Archives of Medical Research. Oct, 2020 | Pubmed ID: 32611485 Prognostic Significance of the MAD1L1 1673 G: A Polymorphism in Ovarian Adenocarcinomas Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion. May, 2020 | Pubmed ID: 32488223 What is the Impact of Radical Hysterectomy on Endometrial Cancer with Cervical Involvement? World Journal of Surgical Oncology. May, 2020 | Pubmed ID: 32438919 MicroRNAs in Tumor Cell Metabolism: Roles and Therapeutic Opportunities Frontiers in Oncology. 2019 | Pubmed ID: 31921661 Airborne Particulate Matter Induces Mitotic Slippage and Chromosomal Missegregation Through Disruption of the Spindle Assembly Checkpoint (SAC) Chemosphere. Nov, 2019 | Pubmed ID: 31280048 Prognostic Factors for Overall Survival in Patients with Chronic Myeloid Leukemia Treated with Imatinib at the National Cancer Institute - Mexico, from 2000 to 2016 Cancer Medicine. Jun, 2019 | Pubmed ID: 31050162 Extracellular Vesicle-enriched MicroRNAs Interact in the Association Between Long-term Particulate Matter and Blood Pressure in Elderly Men Environmental Research. 11, 2018 | Pubmed ID: 30216846 The Use of Long Non-coding RNAs As Prognostic Biomarkers and Therapeutic Targets in Prostate Cancer Oncotarget. Apr, 2018 | Pubmed ID: 29755696 Loss of Nuclear NOTCH1, but Not Its Negative Regulator NUMB, is an Independent Predictor of Cervical Malignancy Oncotarget. Apr, 2018 | Pubmed ID: 29721172 CTCF-KDM4A Complex Correlates with Histone Modifications That Negatively Regulate Gene Expression in Cancer Cell Lines Oncotarget. Mar, 2018 | Pubmed ID: 29682202 Corrigendum to "APOE ε4 Allele Modifies the Association of Lead Exposure with Age-related Cognitive Decline in Older Individuals" [Environ. Res. 151 (2016) 101-105] Environmental Research. 08, 2018 | Pubmed ID: 29183624 Association of Air Particulate Pollution with Bone Loss over Time and Bone Fracture Risk: Analysis of Data from Two Independent Studies The Lancet. Planetary Health. Nov, 2017 | Pubmed ID: 29527596 Regulated Expression of the LncRNA TERRA and Its Impact on Telomere Biology Mechanisms of Ageing and Development. Oct, 2017 | Pubmed ID: 28888705 SOX2 As a New Regulator of HPV16 Transcription Viruses. Jul, 2017 | Pubmed ID: 28678184 Centromeric Non-coding Transcription: Opening the Black Box of Chromosomal Instability? Current Genomics. Jun, 2017 | Pubmed ID: 28603453 Prognostic Significance of Promoter CpG Island Methylation of Obesity-related Genes in Patients with Nonmetastatic Renal Cell Carcinoma Cancer. Sep, 2017 | Pubmed ID: 28543182 Tumor Suppressor MiR-29c Regulates Radioresistance in Lung Cancer Cells Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Mar, 2017 | Pubmed ID: 28345453 Airborne Particulate Matter in Vitro Exposure Induces Cytoskeleton Remodeling Through Activation of the ROCK-MYPT1-MLC Pathway in A549 Epithelial Lung Cells Toxicology Letters. Apr, 2017 | Pubmed ID: 28279687 Radiotherapy for Metastatic Breast Cancer in Mexico: Results from the 2015 National Survey Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion. 2017 | Pubmed ID: 28239177 BUB1 and SURVIVIN Proteins Are Not Degraded After a Prolonged Mitosis and Accumulate in the Nuclei of HCT116 Cells Cell Death Discovery. 2016 | Pubmed ID: 27818790 Comprehensive Transcriptome Analysis Identifies Pathways with Therapeutic Potential in Locally Advanced Cervical Cancer Gynecologic Oncology. Nov, 2016 | Pubmed ID: 27581326 APOE ε4 Allele Modifies the Association of Lead Exposure with Age-related Cognitive Decline in Older Individuals Environmental Research. 11, 2016 | Pubmed ID: 27474937 MiR-125b-1 is Repressed by Histone Modifications in Breast Cancer Cell Lines SpringerPlus. 2016 | Pubmed ID: 27386402 MAD2γ, a Novel MAD2 Isoform, Reduces Mitotic Arrest and is Associated with Resistance in Testicular Germ Cell Tumors Cell Cycle (Georgetown, Tex.). Aug, 2016 | Pubmed ID: 27315568 Clinical Prognostic Factors in Adults with Astrocytoma: Historic Cohort Clinical Neurology and Neurosurgery. Jul, 2016 | Pubmed ID: 27208871 Methylation of DAPK and THBS1 Genes in Esophageal Gastric-type Columnar Metaplasia World Journal of Gastroenterology. May, 2016 | Pubmed ID: 27182166 Genomic DNA Hypomethylation and Risk of Renal Cell Carcinoma: A Case-Control Study Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2016 | Pubmed ID: 26655847 Internalization of Titanium Dioxide Nanoparticles by Glial Cells is Given at Short Times and is Mainly Mediated by Actin Reorganization-dependent Endocytosis Neurotoxicology. Dec, 2015 | Pubmed ID: 26340880 Revealing the Molecular Portrait of Triple Negative Breast Tumors in an Understudied Population Through Omics Analysis of Formalin-Fixed and Paraffin-Embedded Tissues PloS One. 2015 | Pubmed ID: 25961742 Metaplastic Breast Cancer: a Comparison Between the Most Common Histologies with Poor Immunohistochemistry Factors BMC Cancer. Feb, 2015 | Pubmed ID: 25881163 The Role of the Histone Demethylase KDM4A in Cancer Cancer Genetics. May, 2015 | Pubmed ID: 25633974 Significant Clinical Impact of Recurrent BRCA1 and BRCA2 Mutations in Mexico Cancer. Feb, 2015 | Pubmed ID: 25236687 Differential Distribution of HP1 Proteins After Trichostatin a Treatment Influences Chromosomal Stability in HCT116 and WI-38 Cells Cell Division. 2014 | Pubmed ID: 25729403 Influence of Multiple APOE Genetic Variants on Cognitive Function in a Cohort of Older Men - Results from the Normative Aging Study BMC Psychiatry. Aug, 2014 | Pubmed ID: 25085564 MicroRNAs in Cervical Cancer: Evidences for a MiRNA Profile Deregulated by HPV and Its Impact on Radio-resistance Molecules (Basel, Switzerland). May, 2014 | Pubmed ID: 24840898 Cytoplasmic P21(CIP1/WAF1), ERK1/2 Activation, and Cytoskeletal Remodeling Are Associated with the Senescence-like Phenotype After Airborne Particulate Matter (PM(10)) Exposure in Lung Cells Toxicology Letters. Feb, 2014 | Pubmed ID: 24291038 The MAD1 1673 G → A Polymorphism Alters the Function of the Mitotic Spindle Assembly Checkpoint and is Associated with a Worse Response to Induction Chemotherapy and Sensitivity to Treatment in Patients with Advanced Epithelial Ovarian Cancer Pharmacogenetics and Genomics. Apr, 2013 | Pubmed ID: 23407047 Impact of Diabetes and Hyperglycemia on Survival in Advanced Breast Cancer Patients Experimental Diabetes Research. 2012 | Pubmed ID: 22919369 Disruption of CTCF at the MiR-125b1 Locus in Gynecological Cancers BMC Cancer. Jan, 2012 | Pubmed ID: 22277129 Assembling Pieces of the Centromere Epigenetics Puzzle Epigenetics. Jan, 2012 | Pubmed ID: 22207360 Satellite 2 Demethylation Induced by 5-azacytidine is Associated with Missegregation of Chromosomes 1 and 16 in Human Somatic Cells Mutation Research. Jan, 2012 | Pubmed ID: 22032830 The Role of Alternative MRNA Splicing in Chromosome Instability Mutation Research. Dec, 2010 | Pubmed ID: 20932937 The Epigenetic Origin of Aneuploidy Current Genomics. Mar, 2008 | Pubmed ID: 19424483 Valproic Acid As Epigenetic Cancer Drug: Preclinical, Clinical and Transcriptional Effects on Solid Tumors Cancer Treatment Reviews. May, 2008 | Pubmed ID: 18226465 S-adenosyl-L-methionine Counteracts Mitotic Disturbances and Cytostatic Effects Induced by Sodium Arsenite in HeLa Cells Mutation Research. Jan, 2008 | Pubmed ID: 17888458 Prevention of Aneuploidy by S-adenosyl-methionine in Human Cells Treated with Sodium Arsenite Mutation Research. Apr, 2007 | Pubmed ID: 17241646 Antisense Oligonucleotides as a Tool for Prolonged Knockdown of Nuclear lncRNAs in Human Cell Lines Rogelio Montiel-Manriquez1, Clementina Castro-Hernández1, Cristian Arriaga-Canon1, Luis A. Herrera1,2 1Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, 2Escuela de Medicina y Ciencias de la Salud, Tecnológico de Monterrey JoVE 65124 Cancer Research
Antisense Oligonucleotides as a Tool for Prolonged Knockdown of Nuclear lncRNAs in Human Cell Lines Rogelio Montiel-Manriquez1, Clementina Castro-Hernández1, Cristian Arriaga-Canon1, Luis A. Herrera1,2 1Unidad de Investigación Biomédica en Cáncer, Instituto Nacional de Cancerología-Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, 2Escuela de Medicina y Ciencias de la Salud, Tecnológico de Monterrey JoVE 65124 Cancer Research