Martin E. Schwab

Brain Research Institute, University of Zurich

Affiliated withUniversity of Zurich ETH Zurich

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 19	2015

Other Publications

Article	Year
Repair of the injured spinal cord. A joint approach of basic and clinical research. Neuro-degenerative diseases\| PubMed ID: 17429219	2007
Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans? Nature medicine\| PubMed ID: 17479102	2007
The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model. EMBO reports\| PubMed ID: 17039253	2006
Anti-Nogo-A antibody treatment enhances sprouting of corticospinal axons rostral to a unilateral cervical spinal cord lesion in adult macaque monkey. The Journal of comparative neurology\| PubMed ID: 17394135	2007
Regenerative Nerve Fiber Growth in the Adult Central Nervous System. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society\| PubMed ID: 11390807	1998
Repairing the injured spinal cord. Science (New York, N.Y.)\| PubMed ID: 11834824	2002
Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat. Annals of neurology\| PubMed ID: 11921049	2002
Patterns of Nogo mRNA and protein expression in the developing and adult rat and after CNS lesions. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11978832	2002
Red nucleus projections to distinct motor neuron pools in the rat spinal cord. The Journal of comparative neurology\| PubMed ID: 12115698	2002
Electromyographic activity associated with spontaneous functional recovery after spinal cord injury in rats. The European journal of neuroscience\| PubMed ID: 12169107	2002
Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12177206	2002
Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury. The Journal of cell biology\| PubMed ID: 12379801	2002
Reorganization of descending motor tracts in the rat spinal cord. The European journal of neuroscience\| PubMed ID: 12431229	2002
Increasing plasticity and functional recovery of the lesioned spinal cord. Progress in brain research\| PubMed ID: 12440377	2002
Genomic structure and functional characterisation of the promoters of human and mouse nogo/rtn4. Journal of molecular biology\| PubMed ID: 12488097	2003
Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 12571447	2003
Do cancer cells die because of Nogo-B? Oncogene\| PubMed ID: 12618765	2003
Nogo and its paRTNers. Trends in cell biology\| PubMed ID: 12667756	2003
Molecular analysis of Nogo expression in the hippocampus during development and following lesion and seizure. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12692091	2003
Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury. Neuron\| PubMed ID: 12718855	2003
Sequential loss of myelin proteins during Wallerian degeneration in the rat spinal cord. Glia\| PubMed ID: 12730963	2003
Cell-autonomous mechanisms and myelin-associated factors contribute to the development of Purkinje axon intracortical plexus in the rat cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12805301	2003
A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12832288	2003
Functional reorganization of the motor cortex in adult rats after cortical lesion and treatment with monoclonal antibody IN-1. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12832504	2003
Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12843238	2003
Identification of Nogo-66 receptor (NgR) and homologous genes in fish. Molecular biology and evolution\| PubMed ID: 12949137	2004
Inflammation, degeneration and regeneration in the injured spinal cord: insights from DNA microarrays. Trends in neurosciences\| PubMed ID: 14522149	2003
Rapid induction of autoantibodies against Nogo-A and MOG in the absence of an encephalitogenic T cell response: implication for immunotherapeutic approaches in neurological diseases. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 14563689	2003
Serum and cerebrospinal fluid antibodies to Nogo-A in patients with multiple sclerosis and acute neurological disorders. Journal of neuroimmunology\| PubMed ID: 14644040	2003
The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nature neuroscience\| PubMed ID: 14966523	2004
Nogo and axon regeneration. Current opinion in neurobiology\| PubMed ID: 15018947	2004
Identification of two NOGO/RTN4 genes and analysis of Nogo-A expression in Xenopus laevis. Molecular and cellular neurosciences\| PubMed ID: 15019938	2004
Targeting experimental autoimmune encephalomyelitis lesions to a predetermined axonal tract system allows for refined behavioral testing in an animal model of multiple sclerosis. The American journal of pathology\| PubMed ID: 15039233	2004
Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions. Molecular and cellular neurosciences\| PubMed ID: 15121177	2004
Behavioral testing strategies in a localized animal model of multiple sclerosis. Journal of neuroimmunology\| PubMed ID: 15265674	2004
Remodeling of axonal connections contributes to recovery in an animal model of multiple sclerosis. The Journal of experimental medicine\| PubMed ID: 15492125	2004
Nogo-A, -B, and -C are found on the cell surface and interact together in many different cell types. The Journal of biological chemistry\| PubMed ID: 15640160	2005
Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15689553	2005
In vivo imaging of axonal degeneration and regeneration in the injured spinal cord. Nature medicine\| PubMed ID: 15821747	2005
Analysis of the reticulon gene family demonstrates the absence of the neurite growth inhibitor Nogo-A in fish. Molecular biology and evolution\| PubMed ID: 15858203	2005
Delayed treatment with monoclonal antibody IN-1 1 week after stroke results in recovery of function and corticorubral plasticity in adult rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 15889044	2005
Dendritic plasticity in the adult rat following middle cerebral artery occlusion and Nogo-a neutralization. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 16033928	2006
Nogo-A antibody improves regeneration and locomotion of spinal cord-injured rats. Annals of neurology\| PubMed ID: 16173073	2005
Recovery and brain reorganization after stroke in adult and aged rats. Annals of neurology\| PubMed ID: 16315284	2005
Inhibition of Nogo: a key strategy to increase regeneration, plasticity and functional recovery of the lesioned central nervous system. Annals of medicine\| PubMed ID: 16338758	2005
BMP2 and FGF2 cooperate to induce neural-crest-like fates from fetal and adult CNS stem cells. Journal of cell science\| PubMed ID: 16339968	2005
Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cord. Molecular and cellular neurosciences\| PubMed ID: 16626970	2006
Intrathecally infused antibodies against Nogo-A penetrate the CNS and downregulate the endogenous neurite growth inhibitor Nogo-A. Molecular and cellular neurosciences\| PubMed ID: 16697217	2006
Nogo-A-deficient mice reveal strain-dependent differences in axonal regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16723516	2006
Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates. Nature medicine\| PubMed ID: 16819551	2006
Sprouting, regeneration and circuit formation in the injured spinal cord: factors and activity. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 16939978	2006
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors. Journal of neurochemistry\| PubMed ID: 17488279	2007
Intrathecal treatment with anti-Nogo-A antibody improves functional recovery in adult rats after stroke. Experimental brain research\| PubMed ID: 17717658	2007
Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expression. Journal of neurosurgery\| PubMed ID: 17937233	2007
Synaptic destabilization by neuronal Nogo-A. Brain cell biology\| PubMed ID: 17957480	2006
Nogo-A inhibition induces recovery from neglect in rats. Behavioural brain research\| PubMed ID: 17963852	2008
Nogo receptor antagonizes p75NTR-dependent motor neuron death. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18182498	2008
Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion. BMC neuroscience\| PubMed ID: 18194520	2008
Lamina-specific restoration of serotonergic projections after Nogo-A antibody treatment of spinal cord injury in rats. The European journal of neuroscience\| PubMed ID: 18215231	2008
Improving outcome after stroke: overcoming the translational roadblock. Cerebrovascular diseases (Basel, Switzerland)\| PubMed ID: 18292653	2008
Nogo-A expression after focal ischemic stroke in the adult rat. Stroke; a journal of cerebral circulation\| PubMed ID: 18467652	2008
DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis. European journal of pharmacology\| PubMed ID: 18495110	2008
Nogo-A and myelin-associated glycoprotein differently regulate oligodendrocyte maturation and myelin formation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18632947	2008
Constraint-induced movement therapy in the adult rat after unilateral corticospinal tract injury. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18799672	2008
Neutralization of the membrane protein Nogo-A enhances growth and reactive sprouting in established organotypic hippocampal slice cultures. The European journal of neuroscience\| PubMed ID: 18973596	2008
Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron\| PubMed ID: 18995811	2008
Functional reorganization in rat somatosensory cortex assessed by fMRI: elastic image registration based on structural landmarks in fMRI images and application to spinal cord injured rats. NeuroImage\| PubMed ID: 19015037	2009
Neuronal Nogo-A modulates growth cone motility via Rho-GTP/LIMK1/cofilin in the unlesioned adult nervous system. The Journal of biological chemistry\| PubMed ID: 19208621	2009
Anti-Nogo-A antibody treatment promotes recovery of manual dexterity after unilateral cervical lesion in adult primates--re-examination and extension of behavioral data. The European journal of neuroscience\| PubMed ID: 19291225	2009
Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons. Experimental neurology\| PubMed ID: 19320005	2009
Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury. Brain : a journal of neurology\| PubMed ID: 19372269	2009
Nogo in the Mammalian cochlea. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology\| PubMed ID: 19546827	2009
Functional and anatomical reorganization of the sensory-motor cortex after incomplete spinal cord injury in adult rats. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19793979	2009
Rewiring of hindlimb corticospinal neurons after spinal cord injury. Nature neuroscience\| PubMed ID: 20010824	2010
Cognitive recovery in the aged rat after stroke and anti-Nogo-A immunotherapy. Behavioural brain research\| PubMed ID: 20035795	2010
Constitutive genetic deletion of the growth regulator Nogo-A induces schizophrenia-related endophenotypes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20071518	2010
Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling. The Journal of cell biology\| PubMed ID: 20083601	2010
Role of Nogo-A in neuronal survival in the reperfused ischemic brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 20087369	2010
Nogo-a regulates neural precursor migration in the embryonic mouse cortex. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 20093372	2010
Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development (Cambridge, England)\| PubMed ID: 20573699	2010
Nogo-A antibodies and training reduce muscle spasms in spinal cord-injured rats. Annals of neurology\| PubMed ID: 20582944	2010
Anti-Nogo on the go: from animal models to a clinical trial. Annals of the New York Academy of Sciences\| PubMed ID: 20590535	2010
Profiling locomotor recovery: comprehensive quantification of impairments after CNS damage in rodents. Nature methods\| PubMed ID: 20836253	2010
Nogo-A stabilizes the architecture of hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20926648	2010
Functions of Nogo proteins and their receptors in the nervous system. Nature reviews. Neuroscience\| PubMed ID: 21045861	2010
Delayed anti-nogo-a therapy improves function after chronic stroke in adult rats. Stroke; a journal of cerebral circulation\| PubMed ID: 21088244	2011
How hard is the CNS hardware? Nature neuroscience\| PubMed ID: 21102566	2010
NogoA restricts synaptic plasticity in the adult hippocampus on a fast time scale. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21262805	2011
Anti-Nogo-A and training: can one plus one equal three? Experimental neurology\| PubMed ID: 21530508	2012
Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome. Brain : a journal of neurology\| PubMed ID: 21752788	2011
Delayed anti-nogo-a antibody application after spinal cord injury shows progressive loss of responsiveness. Journal of neurotrauma\| PubMed ID: 21815784	2012
Heterogeneous spine loss in layer 5 cortical neurons after spinal cord injury. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 21840844	2012
Rehabilitative training following unilateral pyramidotomy in adult rats improves forelimb function in a non-task-specific way. Experimental neurology\| PubMed ID: 21867701	2011
Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. The European journal of neuroscience\| PubMed ID: 21995852	2011
Drug research: plug the real brain drain. Nature\| PubMed ID: 22422244	2012
Tail spasms in rat spinal cord injury: changes in interneuronal connectivity. Experimental neurology\| PubMed ID: 22569103	2012
The role of Nogo-A in axonal plasticity, regrowth and repair. Cell and tissue research\| PubMed ID: 22588543	2012
Influence of anti-Nogo-A antibody treatment on the reorganization of callosal connectivity of the premotor cortical areas following unilateral lesion of primary motor cortex (M1) in adult ma... Experimental brain research\| PubMed ID: 22990293	2012
Defeating inhibition of regeneration by scar and myelin components. Handbook of clinical neurology\| PubMed ID: 23098733	2012
The rocky road to translation in spinal cord repair. Annals of neurology\| PubMed ID: 23109144	2012
Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve. Neurobiology of disease\| PubMed ID: 23194670	2013
Distinct roles of Nogo-a and Nogo receptor 1 in the homeostatic regulation of adult neural stem cell function and neuroblast migration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23223298	2012
Nogo-A downregulation improves insulin secretion in mice. Diabetes\| PubMed ID: 23274909	2013
Neuronal Nogo-A negatively regulates dendritic morphology and synaptic transmission in the cerebellum. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23277570	2013
Nogo and Nogo receptor: relevance to schizophrenia? Neurobiology of disease\| PubMed ID: 23369871	2013
Synthetic microRNA-mediated downregulation of Nogo-A in transgenic rats reveals its role as regulator of synaptic plasticity and cognitive function. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23576723	2013
Nogo-A is a negative regulator of CNS angiogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23625008	2013
Nogo-A represses anatomical and synaptic plasticity in the central nervous system. Physiology (Bethesda, Md.)\| PubMed ID: 23636261	2013
Combination treatment with anti-Nogo-A and chondroitinase ABC is more effective than single treatments at enhancing functional recovery after spinal cord injury. The European journal of neuroscience\| PubMed ID: 23790207	2013
Comparison of functional recovery of manual dexterity after unilateral spinal cord lesion or motor cortex lesion in adult macaque monkeys. Frontiers in neurology\| PubMed ID: 23885254	2013
Long-term motor cortical map changes following unilateral lesion of the hand representation in the motor cortex in macaque monkeys showing functional recovery of hand functions. Restorative neurology and neuroscience\| PubMed ID: 24064551	2013
Infusion of anti-Nogo-A antibodies in adult rats increases growth and synapse related proteins in the absence of behavioral alterations. Experimental neurology\| PubMed ID: 24076004	2013
Upregulation of axon guidance molecules in the adult central nervous system of Nogo-A knockout mice restricts neuronal growth and regeneration. The European journal of neuroscience\| PubMed ID: 24103058	2013
Deep brain stimulation of the midbrain locomotor region improves paretic hindlimb function after spinal cord injury in rats. Science translational medicine\| PubMed ID: 24154600	2013
An open source based high content screening method for cell biology laboratories investigating cell spreading and adhesion. PloS one\| PubMed ID: 24205161	2013
Nogo-A downregulation impairs place avoidance in the Carousel maze but not spatial memory in the Morris water maze. Neurobiology of learning and memory\| PubMed ID: 24211256	2014
Rewiring of the corticospinal tract in the adult rat after unilateral stroke and anti-Nogo-A therapy. Brain : a journal of neurology\| PubMed ID: 24355710	2014
The neurite growth inhibitory protein Nogo-A has diverse roles in adhesion and migration. Cell adhesion & migration\| PubMed ID: 24401759	2013
How Plastic Is the Brain after a Stroke? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry\| PubMed ID: 24402612	2014
Nogo-A: Multiple Roles in CNS Development, Maintenance, and Disease. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry\| PubMed ID: 24402613	2014
Finding an optimal rehabilitation paradigm after stroke: enhancing fiber growth and training of the brain at the right moment. Frontiers in human neuroscience\| PubMed ID: 24416012	2014
The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity. PLoS biology\| PubMed ID: 24453941	2014
Protein synthesis dependence of growth cone collapse induced by different Nogo-A-domains. PloS one\| PubMed ID: 24489789	2014
High-Impact, Self-Motivated Training Within an Enriched Environment With Single Animal Tracking Dose-Dependently Promotes Motor Skill Acquisition and Functional Recovery. Neurorehabilitation and neural repair\| PubMed ID: 24519022	2014
Sprouting of brainstem-spinal tracts in response to unilateral motor cortex stroke in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24573294	2014
Nogo limits neural plasticity and recovery from injury. Current opinion in neurobiology\| PubMed ID: 24632308	2014
Nogo-A-deficient Transgenic Rats Show Deficits in Higher Cognitive Functions, Decreased Anxiety, and Altered Circadian Activity Patterns. Frontiers in behavioral neuroscience\| PubMed ID: 24672453	2014
Chasing central nervous system plasticity: the brainstem's contribution to locomotor recovery in rats with spinal cord injury. Brain : a journal of neurology\| PubMed ID: 24736305	2014
Lost in the jungle: new hurdles for optic nerve axon regeneration. Trends in neurosciences\| PubMed ID: 24874558	2014
Neutralization of Nogo-A enhances synaptic plasticity in the rodent motor cortex and improves motor learning in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24966370	2014
New mouse retinal stroke model reveals direction-selective circuit damage linked to permanent optokinetic response loss. Investigative ophthalmology & visual science\| PubMed ID: 24970264	2014
Finding an optimal rehabilitation paradigm after stroke: enhancing fiber growth and training of the brain at the right moment. Frontiers in human neuroscience\| PubMed ID: 25018717	2014
The Ephrin receptor EphA4 restricts axonal sprouting and enhances branching in the injured mouse optic nerve. The European journal of neuroscience\| PubMed ID: 25041248	2014
Bridging the gap: a reticulo-propriospinal detour bypassing an incomplete spinal cord injury. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25274818	2014
Nogo-A deletion increases the plasticity of the optokinetic response and changes retinal projection organization in the adult mouse visual system. Brain structure & function\| PubMed ID: 25284126	2014
Anti-Nogo-A antibody: a treatment option for neurogenic lower urinary tract dysfunction? BJU international\| PubMed ID: 25430943	2015
Central nervous system regenerative failure: role of oligodendrocytes, astrocytes, and microglia. Cold Spring Harbor perspectives in biology\| PubMed ID: 25475091	2015
Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain. Nature protocols\| PubMed ID: 25502884	2015
A novel urodynamic model for lower urinary tract assessment in awake rats. BJU international\| PubMed ID: 25597776	2015