Rebecca L. Hull Division of Metabolism, Endocrinology and Nutrition VA Puget Sound Health Care System Biography Publications Institution JoVE Articles Rebecca L. Hull has not added a biography. If you are Rebecca L. Hull and would like to personalize this page please email our Author Liaison for assistance. Publications Use of the PET Ligand Florbetapir for in Vivo Imaging of Pancreatic Islet Amyloid Deposits in HIAPP Transgenic Mice Diabetologia. 10, 2018 | Pubmed ID: 30046852 Neprilysin Deficiency Is Associated With Expansion of Islet β-Cell Mass in High Fat-Fed Mice The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 07, 2018 | Pubmed ID: 29553871 Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure Diabetes Care. 04, 2018 | Pubmed ID: 29437698 Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation Diabetes. 10, 2017 | Pubmed ID: 28729244 The Islet Endothelial Cell: a Novel Contributor to Beta Cell Secretory Dysfunction in Diabetes Diabetologia. 06, 2017 | Pubmed ID: 28396983 The S20G Substitution in HIAPP is More Amyloidogenic and Cytotoxic Than Wild-type HIAPP in Mouse Islets Diabetologia. 10, 2016 | Pubmed ID: 27393137 Human Type 1 Diabetes Is Characterized by an Early, Marked, Sustained, and Islet-Selective Loss of Sympathetic Nerves Diabetes. 08, 2016 | Pubmed ID: 27207540 Matrix Metalloproteinase-9 Protects Islets from Amyloid-induced Toxicity The Journal of Biological Chemistry. Dec, 2015 | Pubmed ID: 26483547 Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2 The Journal of Biological Chemistry. Oct, 2015 | Pubmed ID: 26342077 Human Islets Have Fewer Blood Vessels Than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 08, 2015 | Pubmed ID: 26216139 Hyaluronan: A Mediator of Islet Dysfunction and Destruction in Diabetes? The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 08, 2015 | Pubmed ID: 26216136 Histochemical Insights into Pancreatic Islet Biology The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 08, 2015 | Pubmed ID: 26216132 Islet Amyloid Formation is an Important Determinant for Inducing Islet Inflammation in High-fat-fed Human IAPP Transgenic Mice Diabetologia. Sep, 2014 | Pubmed ID: 24965964 One Year of Sitagliptin Treatment Protects Against Islet Amyloid-associated β-cell Loss and Does Not Induce Pancreatitis or Pancreatic Neoplasia in Mice American Journal of Physiology. Endocrinology and Metabolism. Aug, 2013 | Pubmed ID: 23736544 Rosiglitazone Treatment Does Not Decrease Amyloid Deposition in Transplanted Islets from Transgenic Mice Expressing Human Islet Amyloid Polypeptide Transplantation Proceedings. Mar, 2013 | Pubmed ID: 23267797 Matrix Metalloproteinase-9 Reduces Islet Amyloid Formation by Degrading Islet Amyloid Polypeptide The Journal of Biological Chemistry. Feb, 2013 | Pubmed ID: 23229548 β-cell Loss and β-cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition The American Journal of Pathology. Jun, 2011 | Pubmed ID: 21641386 Activation of the NLRP3 Inflammasome by Islet Amyloid Polypeptide Provides a Mechanism for Enhanced IL-1β in Type 2 Diabetes Nature Immunology. Oct, 2010 | Pubmed ID: 20835230 Inhibition of Glycosaminoglycan Synthesis and Protein Glycosylation with WAS-406 and Azaserine Result in Reduced Islet Amyloid Formation in Vitro American Journal of Physiology. Cell Physiology. Nov, 2007 | Pubmed ID: 17804609 Progressive Loss of Beta-cell Function Leads to Worsening Glucose Tolerance in First-degree Relatives of Subjects with Type 2 Diabetes Diabetes Care. Mar, 2007 | Pubmed ID: 17327340 Identification of the Amyloid-degrading Enzyme Neprilysin in Mouse Islets and Potential Role in Islet Amyloidogenesis Diabetes. Feb, 2007 | Pubmed ID: 17259373 Glucose- and Time-dependence of Islet Amyloid Formation in Vitro Biochemical and Biophysical Research Communications. Mar, 2007 | Pubmed ID: 17222388 Superiority of the Modification of Diet in Renal Disease Equation over the Cockcroft-Gault Equation in Screening for Impaired Kidney Function in Japanese Americans Diabetes Research and Clinical Practice. Aug, 2007 | Pubmed ID: 17141914 Mechanisms Linking Obesity to Insulin Resistance and Type 2 Diabetes Nature. Dec, 2006 | Pubmed ID: 17167471 Impact of Differences in Fasting Glucose and Glucose Tolerance on the Hyperbolic Relationship Between Insulin Sensitivity and Insulin Responses Diabetes Care. Feb, 2006 | Pubmed ID: 16443887 Increased Dietary Fat Promotes Islet Amyloid Formation and Beta-cell Secretory Dysfunction in a Transgenic Mouse Model of Islet Amyloid Diabetes. Feb, 2003 | Pubmed ID: 12540610 Beta-cell Function is a Major Contributor to Oral Glucose Tolerance in High-risk Relatives of Four Ethnic Groups in the U.S Diabetes. Jul, 2002 | Pubmed ID: 12086947 The Concurrent Accumulation of Intra-abdominal and Subcutaneous Fat Explains the Association Between Insulin Resistance and Plasma Leptin Concentrations : Distinct Metabolic Effects of Two Fat Compartments Diabetes. Apr, 2002 | Pubmed ID: 11916919 Acclimation Prior to an Intraperitoneal Insulin Tolerance Test to Mitigate Stress-Induced Hyperglycemia in Conscious Mice Rebecca L. Hull1,2, Daryl J. Hackney1, Elizabeth L. Giering1,2, Sakeneh Zraika1,2 1Division of Metabolism, Endocrinology and Nutrition, VA Puget Sound Health Care System, 2Department of Medicine, University of Washington JoVE 61179 Medicine
Acclimation Prior to an Intraperitoneal Insulin Tolerance Test to Mitigate Stress-Induced Hyperglycemia in Conscious Mice Rebecca L. Hull1,2, Daryl J. Hackney1, Elizabeth L. Giering1,2, Sakeneh Zraika1,2 1Division of Metabolism, Endocrinology and Nutrition, VA Puget Sound Health Care System, 2Department of Medicine, University of Washington JoVE 61179 Medicine
