Robert N. Weinreb Hamilton Glaucoma Center, Viterbi Family Department of Ophthalmology, Shiley Eye Institute University of California San Diego Biography Publications Institution JoVE Articles Robert N. Weinreb has not added a biography. If you are Robert N. Weinreb and would like to personalize this page please email our Author Liaison for assistance. Publications Intraocular Pressure Measurement in Patients Wearing Filtering Facepiece Masks Journal of Glaucoma. Aug, 2020 | Pubmed ID: 32826763 Short-Term and Long-Term Variability of Intraocular Pressure Measured with an Intraocular Telemetry Sensor in Patients with Glaucoma Ophthalmology. Jul, 2020 | Pubmed ID: 32663530 IOL Power Calculation in the Elderly Population Using the Kane Formula in Comparison to Existing Methods Journal of Cataract and Refractive Surgery. Jul, 2020 | Pubmed ID: 32657905 A Randomized Controlled Trial Comparing Subconjunctival Injection to Direct Scleral Application of Mitomycin C in Trabeculectomy American Journal of Ophthalmology. Jul, 2020 | Pubmed ID: 32645310 Association Between Rates of Retinal Nerve Fiber Layer Thinning After Intraocular Pressure-Lowering Procedures and Disc Hemorrhage Ophthalmology. Glaucoma. Jan-Feb, 2020 | Pubmed ID: 32632404 Long-term Follow-up of Optic Neuropathy in Chronic Low Cerebrospinal Fluid Pressure Monkeys: the Beijing Intracranial and Intraocular Pressure (iCOP) Study Science China. Life Sciences. Jun, 2020 | Pubmed ID: 32567001 Weekly and Seasonal Changes of Intraocular Pressure Measured with an Implanted Intraocular Telemetry Sensor The British Journal of Ophthalmology. Jun, 2020 | Pubmed ID: 32499329 Finite Element Analysis of Trans-lamina Cribrosa Pressure Difference on Optic Nerve Head Biomechanics: the Beijing Intracranial and Intraocular Pressure Study Science China. Life Sciences. May, 2020 | Pubmed ID: 32447541 Smart Electronic Eyedrop Bottle for Unobtrusive Monitoring of Glaucoma Medication Adherence Sensors (Basel, Switzerland). Apr, 2020 | Pubmed ID: 32366013 Glaucomatous Vertical Vessel Density Asymmetry of the Temporal Raphe Detected with Optical Coherence Tomography Angiography Scientific Reports. Apr, 2020 | Pubmed ID: 32322012 Loss of AKAP1 Triggers Drp1 Dephosphorylation-mediated Mitochondrial Fission and Loss in Retinal Ganglion Cells Cell Death & Disease. Apr, 2020 | Pubmed ID: 32312949 Detection of Progression With 10-2 Standard Automated Perimetry: Development and Validation of an Event-Based Algorithm American Journal of Ophthalmology. Aug, 2020 | Pubmed ID: 32278773 The Relationship Between Intraocular Pressure and Rates of Central Versus Peripheral Visual Field Progression Journal of Glaucoma. Jun, 2020 | Pubmed ID: 32251071 Matrix Metalloproteinases and Glaucoma Treatment Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. May, 2020 | Pubmed ID: 32233938 Deep-layer Microvasculature Dropout in Preperimetric Glaucoma Patients Journal of Glaucoma. Jun, 2020 | Pubmed ID: 32205833 Current Knowledge and Attitudes Concerning Cost-Effectiveness in Glaucoma Pharmacotherapy: A Glaucoma Specialists Focus Group Study Clinical Ophthalmology (Auckland, N.Z.). 2020 | Pubmed ID: 32184559 Characteristics of Focal Gamma Zone Parapapillary Atrophy Investigative Ophthalmology & Visual Science. 03, 2020 | Pubmed ID: 32176268 Author Correction: Vision-related Quality of Life and Symptom Perception Change over Time in Newly-diagnosed Primary Open Angle Glaucoma Patients Scientific Reports. Mar, 2020 | Pubmed ID: 32144291 Response To: Comparison of Fellow Eye of Acute Primary Angle Closure and Phacomorphic Angle Closure Journal of Glaucoma. May, 2020 | Pubmed ID: 32079992 Diagnostic Ability of Optical Coherence Tomography Angiography Macula Vessel Density for the Diagnosis of Glaucoma Using Difference Scan Sizes Journal of Glaucoma. 04, 2020 | Pubmed ID: 31977545 Accuracy of IOL Power Calculations in the Very Elderly Eye (London, England). Jan, 2020 | Pubmed ID: 31932707 Hypotony Keratopathy Following Trabeculectomy Journal of Glaucoma. Feb, 2020 | Pubmed ID: 31876870 Relationship of Corneal Hysteresis and Anterior Lamina Cribrosa Displacement in Glaucoma American Journal of Ophthalmology. 04, 2020 | Pubmed ID: 31770514 Vessel Density and Retinal Nerve Fibre Layer Thickness Following Acute Primary Angle Closure The British Journal of Ophthalmology. Aug, 2020 | Pubmed ID: 31676595 Review of the Measurement and Management of 24-hour Intraocular Pressure in Patients with Glaucoma Survey of Ophthalmology. Mar - Apr, 2020 | Pubmed ID: 31628907 Inhibition of CAMP/PKA Pathway Protects Optic Nerve Head Astrocytes Against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization Oxidative Medicine and Cellular Longevity. 2019 | Pubmed ID: 31781352 Racial Differences in the Association of Anterior Lamina Cribrosa Surface Depth and Glaucoma Severity in the African Descent and Glaucoma Evaluation Study (ADAGES) Investigative Ophthalmology & Visual Science. 10, 2019 | Pubmed ID: 31661550 Vision-related Quality of Life and Symptom Perception Change over Time in Newly-diagnosed Primary Open Angle Glaucoma Patients Scientific Reports. 05, 2019 | Pubmed ID: 31043703 Association of Macular and Circumpapillary Microvasculature with Visual Field Sensitivity in Advanced Glaucoma American Journal of Ophthalmology. 08, 2019 | Pubmed ID: 30878489 Prophylactic Laser Iridotomy in Primary Angle-closure Suspects Lancet (London, England). 04, 2019 | Pubmed ID: 30878227 Measurement Floors and Dynamic Ranges of OCT and OCT Angiography in Glaucoma Ophthalmology. 07, 2019 | Pubmed ID: 30858023 Changes in Optic Nerve Head Vessel Density After Acute Primary Angle Closure Episode Investigative Ophthalmology & Visual Science. 02, 2019 | Pubmed ID: 30721302 Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost Translational Vision Science & Technology. Jan, 2019 | Pubmed ID: 30713809 Comparison of Fellow Eyes of Acute Primary Angle Closure and Phacomorphic Angle Closure Journal of Glaucoma. 03, 2019 | Pubmed ID: 30585936 Parapapillary Deep-Layer Microvasculature Dropout and Visual Field Progression in Glaucoma American Journal of Ophthalmology. 04, 2019 | Pubmed ID: 30578786 Canaloplasty in the Treatment of Open-Angle Glaucoma: A Review of Patient Selection and Outcomes Advances in Therapy. 01, 2019 | Pubmed ID: 30488337 24-Hour Intraocular Pressure Control with Fixed-dose Combination Brinzolamide 1%/Brimonidine 0.2%: A Multicenter, Randomized Trial Ophthalmology. 08, 2019 | Pubmed ID: 30403988 In Reply: Calcium Channel Blockers and Risk of Primary Open-angle Glaucoma Journal of Glaucoma. 03, 2019 | Pubmed ID: 30358648 Association Between Rates of Retinal Nerve Fiber Layer Thinning and Previous Disc Hemorrhage in Glaucoma Ophthalmology. Glaucoma. Jul - Aug, 2018 | Pubmed ID: 32672629 Latanoprost with High Precision, Piezo-print Microdose Delivery for IOP Lowering: Clinical Results of the PG21 Study of 0.4 µg Daily Microdose Clinical Ophthalmology (Auckland, N.Z.). 2018 | Pubmed ID: 30568423 Lamina Cribrosa and Choroid Features and Their Relationship to Stage of Pseudoexfoliation Glaucoma Investigative Ophthalmology & Visual Science. 11, 2018 | Pubmed ID: 30398627 Genome-wide Association Study of Primary Open-angle Glaucoma in Continental and Admixed African Populations Human Genetics. Oct, 2018 | Pubmed ID: 30317457 Racial Differences in Rate of Change of Spectral-Domain Optical Coherence Tomography-Measured Minimum Rim Width and Retinal Nerve Fiber Layer Thickness American Journal of Ophthalmology. 12, 2018 | Pubmed ID: 30195890 Macular Pigment and Visual Function in Patients With Glaucoma: The San Diego Macular Pigment Study Investigative Ophthalmology & Visual Science. 09, 2018 | Pubmed ID: 30193322 Ubiquinol Promotes Retinal Ganglion Cell Survival and Blocks the Apoptotic Pathway in Ischemic Retinal Degeneration Biochemical and Biophysical Research Communications. 09, 2018 | Pubmed ID: 30107910 Optineurin E50K Triggers BDNF Deficiency-mediated Mitochondrial Dysfunction in Retinal Photoreceptor Cell Line Biochemical and Biophysical Research Communications. 09, 2018 | Pubmed ID: 30100066 Conjunctival and Intrascleral Vasculatures Assessed Using Anterior Segment Optical Coherence Tomography Angiography in Normal Eyes American Journal of Ophthalmology. 12, 2018 | Pubmed ID: 30099035 Optic Disc Microvasculature Dropout in Primary Open-angle Glaucoma Measured with Optical Coherence Tomography Angiography PloS One. 2018 | Pubmed ID: 30086177 Oral Memantine for the Treatment of Glaucoma: Design and Results of 2 Randomized, Placebo-Controlled, Phase 3 Studies Ophthalmology. 12, 2018 | Pubmed ID: 30082073 Use of Machine Learning on Contact Lens Sensor-Derived Parameters for the Diagnosis of Primary Open-angle Glaucoma American Journal of Ophthalmology. 10, 2018 | Pubmed ID: 30053471 Classification of Primary Angle Closure Spectrum with Hierarchical Cluster Analysis PloS One. 2018 | Pubmed ID: 30036362 Combined Glaucoma and Cataract Surgery: Comparison of Viscocanalostomy, Endocyclophotocoagulation, and Ab Interno Trabeculectomy Journal of Cataract and Refractive Surgery. May, 2018 | Pubmed ID: 29891153 Retinal Nerve Fiber Layer Features Identified by Unsupervised Machine Learning on Optical Coherence Tomography Scans Predict Glaucoma Progression Investigative Ophthalmology & Visual Science. 06, 2018 | Pubmed ID: 29860461 Deep-Layer Microvasculature Dropout by Optical Coherence Tomography Angiography and Microstructure of Parapapillary Atrophy Investigative Ophthalmology & Visual Science. 04, 2018 | Pubmed ID: 29677362 Optical Coherence Tomography Angiography Macular Vascular Density Measurements and the Central 10-2 Visual Field in Glaucoma Journal of Glaucoma. 06, 2018 | Pubmed ID: 29664832 Reply Ophthalmology. 04, 2018 | Pubmed ID: 29566874 Macular Vessel Density in Glaucomatous Eyes With Focal Lamina Cribrosa Defects Journal of Glaucoma. 04, 2018 | Pubmed ID: 29462015 Elevated Intracellular CAMP Exacerbates Vulnerability to Oxidative Stress in Optic Nerve Head Astrocytes Cell Death & Disease. 02, 2018 | Pubmed ID: 29459737 Reply Ophthalmology. 03, 2018 | Pubmed ID: 29458837 Autotaxin-Lysophosphatidic Acid Pathway in Intraocular Pressure Regulation and Glaucoma Subtypes Investigative Ophthalmology & Visual Science. 02, 2018 | Pubmed ID: 29392315 In Reply: Reproducibility of Central Corneal Thickness Measurements in Healthy and Glaucomatous Eyes Journal of Glaucoma. 02, 2018 | Pubmed ID: 29381565 Baseline 24-2 Central Visual Field Damage Is Predictive of Global Progressive Field Loss American Journal of Ophthalmology. 03, 2018 | Pubmed ID: 29317211 Latanoprostene Bunod 0.024% in Subjects With Open-angle Glaucoma or Ocular Hypertension: Pooled Phase 3 Study Findings Journal of Glaucoma. 01, 2018 | Pubmed ID: 29194198 Anterior Segment Dimensions Following Laser Iridotomy in Acute Primary Angle Closure and Fellow Eyes American Journal of Ophthalmology. 02, 2018 | Pubmed ID: 29191661 Peripapillary and Macular Vessel Density in Patients with Primary Open-Angle Glaucoma and Unilateral Visual Field Loss Ophthalmology. 04, 2018 | Pubmed ID: 29174012 A Longitudinal Analysis of Peripapillary Choroidal Thinning in Healthy and Glaucoma Subjects American Journal of Ophthalmology. 02, 2018 | Pubmed ID: 29103960 Repeatability of Vessel Density Measurements of Optical Coherence Tomography Angiography in Normal and Glaucoma Eyes The British Journal of Ophthalmology. 03, 2018 | Pubmed ID: 28739645 Will Perimetry Be Performed to Monitor Glaucoma in 2025? Ophthalmology. 12, 2017 | Pubmed ID: 28865878 Reproducibility of Central Corneal Thickness Measurements in Healthy and Glaucomatous Eyes Journal of Glaucoma. Sep, 2017 | Pubmed ID: 28816818 Progressive Macula Vessel Density Loss in Primary Open-Angle Glaucoma: A Longitudinal Study American Journal of Ophthalmology. Oct, 2017 | Pubmed ID: 28734815 24-2 Visual Fields Miss Central Defects Shown on 10-2 Tests in Glaucoma Suspects, Ocular Hypertensives, and Early Glaucoma Ophthalmology. 10, 2017 | Pubmed ID: 28551166 Rates of Local Retinal Nerve Fiber Layer Thinning Before and After Disc Hemorrhage in Glaucoma Ophthalmology. 09, 2017 | Pubmed ID: 28499748 Angle Stability and Outflow in Dual Blade Ab Interno Trabeculectomy with Active Versus Passive Chamber Management PloS One. 2017 | Pubmed ID: 28486513 A Comparison of the Diagnostic Ability of Vessel Density and Structural Measurements of Optical Coherence Tomography in Primary Open Angle Glaucoma PloS One. 2017 | Pubmed ID: 28288185 Peripapillary and Macular Vessel Density in Patients with Glaucoma and Single-Hemifield Visual Field Defect Ophthalmology. 05, 2017 | Pubmed ID: 28196732 Steroid-induced Glaucoma in the Pediatric Population Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus. 02, 2017 | Pubmed ID: 28087345 REPRODUCIBILITY OF VESSEL DENSITY MEASUREMENT WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EYES WITH AND WITHOUT RETINOPATHY Retina (Philadelphia, Pa.). Aug, 2017 | Pubmed ID: 27930458 Deep Retinal Layer Microvasculature Dropout Detected by the Optical Coherence Tomography Angiography in Glaucoma Ophthalmology. 12, 2016 | Pubmed ID: 27769587 Relationship Between Optical Coherence Tomography Angiography Vessel Density and Severity of Visual Field Loss in Glaucoma Ophthalmology. 12, 2016 | Pubmed ID: 27726964 Mitochondrial Pathogenic Mechanism and Degradation in Optineurin E50K Mutation-mediated Retinal Ganglion Cell Degeneration Scientific Reports. Sep, 2016 | Pubmed ID: 27654856 Optical Coherence Tomography Angiography Vessel Density in Glaucomatous Eyes with Focal Lamina Cribrosa Defects Ophthalmology. 11, 2016 | Pubmed ID: 27592175 Aqueous Angiography-Mediated Guidance of Trabecular Bypass Improves Angiographic Outflow in Human Enucleated Eyes Investigative Ophthalmology & Visual Science. 09, 2016 | Pubmed ID: 27588614 Association Between Intraocular Pressure and Rates of Retinal Nerve Fiber Layer Loss Measured by Optical Coherence Tomography Ophthalmology. 10, 2016 | Pubmed ID: 27554036 Macular Ganglion Cell Inner Plexiform Layer Thickness in Glaucomatous Eyes with Localized Retinal Nerve Fiber Layer Defects PloS One. 2016 | Pubmed ID: 27537107 Long-term Safety and Efficacy of Latanoprostene Bunod 0.024% in Japanese Subjects with Open-Angle Glaucoma or Ocular Hypertension: The JUPITER Study Advances in Therapy. 09, 2016 | Pubmed ID: 27457469 The Relative Odds of Progressing by Structural and Functional Tests in Glaucoma Investigative Ophthalmology & Visual Science. 07, 2016 | Pubmed ID: 27409501 Latanoprost and Dorzolamide for the Treatment of Pediatric Glaucoma: The Glaucoma Italian Pediatric Study (Gipsy), Design and Baseline Characteristics Advances in Therapy. 08, 2016 | Pubmed ID: 27312975 Reply Ophthalmology. 06, 2016 | Pubmed ID: 27210605 Comparison of Latanoprostene Bunod 0.024% and Timolol Maleate 0.5% in Open-Angle Glaucoma or Ocular Hypertension: The LUNAR Study American Journal of Ophthalmology. Aug, 2016 | Pubmed ID: 27210275 Unsupervised Gaussian Mixture-Model With Expectation Maximization for Detecting Glaucomatous Progression in Standard Automated Perimetry Visual Fields Translational Vision Science & Technology. May, 2016 | Pubmed ID: 27152250 Asymmetric Macular Structural Damage Is Associated With Relative Afferent Pupillary Defects in Patients With Glaucoma Investigative Ophthalmology & Visual Science. Apr, 2016 | Pubmed ID: 27064394 Management of Advanced Glaucoma: Characterization and Monitoring Survey of Ophthalmology. Sep-Oct, 2016 | Pubmed ID: 27018149 Does the Location of Bruch's Membrane Opening Change Over Time? Longitudinal Analysis Using San Diego Automated Layer Segmentation Algorithm (SALSA) Investigative Ophthalmology & Visual Science. Feb, 2016 | Pubmed ID: 26906156 Latanoprostene Bunod 0.024% Versus Timolol Maleate 0.5% in Subjects with Open-Angle Glaucoma or Ocular Hypertension: The APOLLO Study Ophthalmology. May, 2016 | Pubmed ID: 26875002 Aqueous Angiography: Real-Time and Physiologic Aqueous Humor Outflow Imaging PloS One. 2016 | Pubmed ID: 26807586 Rate and Pattern of Rim Area Loss in Healthy and Progressing Glaucoma Eyes Ophthalmology. Apr, 2016 | Pubmed ID: 26746597 REAL-TIME FULL-DEPTH VISUALIZATION OF POSTERIOR OCULAR STRUCTURES: Comparison Between Full-Depth Imaging Spectral Domain Optical Coherence Tomography and Swept-Source Optical Coherence Tomography Retina (Philadelphia, Pa.). Jun, 2016 | Pubmed ID: 26562563 Diagnostic Accuracy of the Spectralis and Cirrus Reference Databases in Differentiating Between Healthy and Early Glaucoma Eyes Ophthalmology. Feb, 2016 | Pubmed ID: 26526632 Evaluation of the Effect of Latanoprostene Bunod Ophthalmic Solution, 0.024% in Lowering Intraocular Pressure over 24 h in Healthy Japanese Subjects Advances in Therapy. Nov, 2015 | Pubmed ID: 26563323 Detecting Glaucomatous Change in Visual Fields: Analysis with an Optimization Framework Journal of Biomedical Informatics. Dec, 2015 | Pubmed ID: 26440445 P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma Molecular Cell. Sep, 2015 | Pubmed ID: 26365380 Retinal Nerve Fiber and Optic Disc Morphology in Patients with Human Immunodeficiency Virus Using the Heidelberg Retina Tomography 3 PloS One. 2015 | Pubmed ID: 26258547 Estimation of 24-Hour Intraocular Pressure Peak Timing and Variation Using a Contact Lens Sensor PloS One. 2015 | Pubmed ID: 26076472 Time Spent in Lateral Sleep Position and Asymmetry in Glaucoma Investigative Ophthalmology & Visual Science. Jun, 2015 | Pubmed ID: 26066754 Diagnostic Ability of Macular Ganglion Cell Inner Plexiform Layer Measurements in Glaucoma Using Swept Source and Spectral Domain Optical Coherence Tomography PloS One. 2015 | Pubmed ID: 25978420 Efficacy of a Contact Lens Sensor for Monitoring 24-h Intraocular Pressure Related Patterns PloS One. 2015 | Pubmed ID: 25942434 Learning from Healthy and Stable Eyes: A New Approach for Detection of Glaucomatous Progression Artificial Intelligence in Medicine. Jun, 2015 | Pubmed ID: 25940856 Analysis of 24-Hour IOP-related Pattern Changes After Medical Therapy Journal of Glaucoma. Jun-Jul, 2015 | Pubmed ID: 25850970 Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent American Journal of Ophthalmology. Jul, 2015 | Pubmed ID: 25849520 Response to Comment on the Article Entitled "effect of Improper Scan Alignment on Retinal Nerve Fiber Layer Thickness Measurements Using Stratus Optical Coherence Tomograph" by Vizzeri G, Et Al Published in J Glaucoma. 2008;17: 341-349 Journal of Glaucoma. Apr-May, 2015 | Pubmed ID: 25822576 Ambulatory 24-h Intraocular Pressure Monitoring in the Management of Glaucoma Current Opinion in Ophthalmology. May, 2015 | Pubmed ID: 25784109 Protection of Injured Retinal Ganglion Cell Dendrites and Unfolded Protein Response Resolution After Long-term Dietary Resveratrol Neurobiology of Aging. May, 2015 | Pubmed ID: 25772060 Differential Protection of Injured Retinal Ganglion Cell Dendrites by Brimonidine Investigative Ophthalmology & Visual Science. Jan, 2015 | Pubmed ID: 25634981 Increased Mitochondrial Fission and Volume Density by Blocking Glutamate Excitotoxicity Protect Glaucomatous Optic Nerve Head Astrocytes Glia. May, 2015 | Pubmed ID: 25557093 A Randomised, Controlled Comparison of Latanoprostene Bunod and Latanoprost 0.005% in the Treatment of Ocular Hypertension and Open Angle Glaucoma: the VOYAGER Study The British Journal of Ophthalmology. Jun, 2015 | Pubmed ID: 25488946 Diagnostic Ability of Retinal Nerve Fiber Layer Imaging by Swept-source Optical Coherence Tomography in Glaucoma American Journal of Ophthalmology. Jan, 2015 | Pubmed ID: 25448991 Glaucoma Progression Detection Using Nonlocal Markov Random Field Prior Journal of Medical Imaging (Bellingham, Wash.). Oct, 2014 | Pubmed ID: 26158069 A Joint Estimation Detection of Glaucoma Progression in 3D Spectral Domain Optical Coherence Tomography Optic Nerve Head Images Proceedings of SPIE--the International Society for Optical Engineering. Mar, 2014 | Pubmed ID: 25606299 Anterior Lamina Cribrosa Insertion in Primary Open-angle Glaucoma Patients and Healthy Subjects PloS One. 2014 | Pubmed ID: 25531761 Assessment of Choroidal Thickness in Healthy and Glaucomatous Eyes Using Swept Source Optical Coherence Tomography PloS One. 2014 | Pubmed ID: 25295876 Author Response: Optic Neuropathy Secondary to Spontaneous Intracranial Hypotension (SIH) As Related to Experimental Primate Model Investigative Ophthalmology & Visual Science. Oct, 2014 | Pubmed ID: 25288677 Glaucoma Considered As an Imbalance Between Production and Clearance of Neurotoxins Investigative Ophthalmology & Visual Science. Aug, 2014 | Pubmed ID: 25159590 Estimated Rates of Retinal Ganglion Cell Loss in Glaucomatous Eyes with and Without Optic Disc Hemorrhages PloS One. 2014 | Pubmed ID: 25157619 Optic Neuropathy Induced by Experimentally Reduced Cerebrospinal Fluid Pressure in Monkeys Investigative Ophthalmology & Visual Science. Apr, 2014 | Pubmed ID: 24736050 Learning from Data: Recognizing Glaucomatous Defect Patterns and Detecting Progression from Visual Field Measurements IEEE Transactions on Bio-medical Engineering. Jul, 2014 | Pubmed ID: 24710816 A Unified Framework for Glaucoma Progression Detection Using Heidelberg Retina Tomograph Images Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society. Jul, 2014 | Pubmed ID: 24709053 Detecting Glaucoma Progression from Localized Rates of Retinal Changes in Parametric and Nonparametric Statistical Framework with Type I Error Control Investigative Ophthalmology & Visual Science. Mar, 2014 | Pubmed ID: 24519427 Outflow Tract Ablation Using a Conditionally Cytotoxic Feline Immunodeficiency Viral Vector Investigative Ophthalmology & Visual Science. Feb, 2014 | Pubmed ID: 24448264 Coenzyme Q10 Ameliorates Oxidative Stress and Prevents Mitochondrial Alteration in Ischemic Retinal Injury Apoptosis : an International Journal on Programmed Cell Death. Apr, 2014 | Pubmed ID: 24337820 Heidelberg Edge Perimetry for the Detection of Early Glaucomatous Damage: a Case Report Case Reports in Ophthalmology. 2013 | Pubmed ID: 24163683 The Relationship Between Visual Field Index and Estimated Number of Retinal Ganglion Cells in Glaucoma PloS One. 2013 | Pubmed ID: 24146895 Likelihood Ratios for Glaucoma Diagnosis Using Spectral-domain Optical Coherence Tomography American Journal of Ophthalmology. Nov, 2013 | Pubmed ID: 23972303 Protection by an Oral Disubstituted Hydroxylamine Derivative Against Loss of Retinal Ganglion Cell Differentiation Following Optic Nerve Crush PloS One. 2013 | Pubmed ID: 23940507 Brimonidine Protects Against Loss of Thy-1 Promoter Activation Following Optic Nerve Crush BMC Ophthalmology. Jun, 2013 | Pubmed ID: 23805828 Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe PloS One. 2013 | Pubmed ID: 23805271 Accuracy of the Heidelberg Spectralis in the Alignment Between Near-infrared Image and Tomographic Scan in a Model Eye: a Multicenter Study American Journal of Ophthalmology. Sep, 2013 | Pubmed ID: 23769196 The Relationship Between Cup-to-disc Ratio and Estimated Number of Retinal Ganglion Cells Investigative Ophthalmology & Visual Science. May, 2013 | Pubmed ID: 23557744 Comparison of Different Spectral Domain OCT Scanning Protocols for Diagnosing Preperimetric Glaucoma Investigative Ophthalmology & Visual Science. May, 2013 | Pubmed ID: 23532529 Diagnostic Ability of Spectral-domain Versus Time-domain Optical Coherence Tomography in Preperimetric Glaucoma Journal of Glaucoma. Jan, 2013 | Pubmed ID: 23377582 Reversal of Lamina Cribrosa Displacement After Intraocular Pressure Reduction in Open-angle Glaucoma Ophthalmology. Mar, 2013 | Pubmed ID: 23218823 Inhibition of Histone Deacetylases 1 and 3 Protects Injured Retinal Ganglion Cells Investigative Ophthalmology & Visual Science. Jan, 2013 | Pubmed ID: 23197683 Brimonidine Blocks Glutamate Excitotoxicity-induced Oxidative Stress and Preserves Mitochondrial Transcription Factor a in Ischemic Retinal Injury PloS One. 2012 | Pubmed ID: 23056591 Diagnosing Preperimetric Glaucoma with Spectral Domain Optical Coherence Tomography Ophthalmology. Nov, 2012 | Pubmed ID: 22883689 Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma PLoS Genetics. 2012 | Pubmed ID: 22570617 OCRL Localizes to the Primary Cilium: a New Role for Cilia in Lowe Syndrome Human Molecular Genetics. Aug, 2012 | Pubmed ID: 22543976 Localized Glaucomatous Change Detection Within the Proper Orthogonal Decomposition Framework Investigative Ophthalmology & Visual Science. Jun, 2012 | Pubmed ID: 22491406 Is Corneal Thickness an Independent Risk Factor for Glaucoma? Ophthalmology. Mar, 2012 | Pubmed ID: 22385483 Association Between Corneal Biomechanical Properties and Glaucoma Severity American Journal of Ophthalmology. Mar, 2012 | Pubmed ID: 22018707 Structure-function Relationships Using the Cirrus Spectral Domain Optical Coherence Tomograph and Standard Automated Perimetry Journal of Glaucoma. Jan, 2012 | Pubmed ID: 21952500 Detection of Retinal Nerve Fibre Layer Progression: Comparison of the Fast and Extended Modes of GDx Guided Progression Analysis The British Journal of Ophthalmology. Dec, 2011 | Pubmed ID: 21979898 Structure-function Relationship in Glaucoma Using Spectral-domain Optical Coherence Tomography Archives of Ophthalmology (Chicago, Ill. : 1960). Jul, 2011 | Pubmed ID: 21746976 Genes of the Unfolded Protein Response Pathway Harbor Risk Alleles for Primary Open Angle Glaucoma PloS One. 2011 | Pubmed ID: 21655191 Comparison of the Diagnostic Accuracies of the Spectralis, Cirrus, and RTVue Optical Coherence Tomography Devices in Glaucoma Ophthalmology. Jul, 2011 | Pubmed ID: 21377735 A Selective Inhibitor of Drp1, Mdivi-1, Increases Retinal Ganglion Cell Survival in Acute Ischemic Mouse Retina Investigative Ophthalmology & Visual Science. Apr, 2011 | Pubmed ID: 21372007 Inducible Nitric Oxide Synthase-mediated Alteration of Mitochondrial OPA1 Expression in Ocular Hypertensive Rats Investigative Ophthalmology & Visual Science. Apr, 2011 | Pubmed ID: 21220562 Agreement Between the Heidelberg Retina Tomograph (HRT) Stereometric Parameters Estimated Using HRT-I and HRT-II Optometry and Vision Science : Official Publication of the American Academy of Optometry. Jan, 2011 | Pubmed ID: 21037499 Agreement Among Spectral-domain Optical Coherence Tomography Instruments for Assessing Retinal Nerve Fiber Layer Thickness American Journal of Ophthalmology. Jan, 2011 | Pubmed ID: 20970108 Effect of Disease Severity and Optic Disc Size on Diagnostic Accuracy of RTVue Spectral Domain Optical Coherence Tomograph in Glaucoma Investigative Ophthalmology & Visual Science. Mar, 2011 | Pubmed ID: 20811060 Increased Optic Atrophy Type 1 Expression Protects Retinal Ganglion Cells in a Mouse Model of Glaucoma Molecular Vision. Jul, 2010 | Pubmed ID: 20664796 Predicting the Onset of Glaucoma: the Confocal Scanning Laser Ophthalmoscopy Ancillary Study to TheOcular Hypertension Treatment Study Ophthalmology. Sep, 2010 | Pubmed ID: 20633931 Determinants of Agreement Between the Confocal Scanning Laser Tomograph and Standardized Assessment of Glaucomatous Progression Ophthalmology. Oct, 2010 | Pubmed ID: 20557941 Comparison of Corneal Biomechanical Properties Between Healthy Blacks and Whites Using the Ocular Response Analyzer American Journal of Ophthalmology. Aug, 2010 | Pubmed ID: 20538248 Comparison of Different Spectral Domain Optical Coherence Tomography Scanning Areas for Glaucoma Diagnosis Ophthalmology. Sep, 2010 | Pubmed ID: 20493529 Effect of Disease Severity on the Performance of Cirrus Spectral-domain OCT for Glaucoma Diagnosis Investigative Ophthalmology & Visual Science. Aug, 2010 | Pubmed ID: 20335619 A Comparison of Rates of Change in Neuroretinal Rim Area and Retinal Nerve Fiber Layer Thickness in Progressive Glaucoma Investigative Ophthalmology & Visual Science. Jul, 2010 | Pubmed ID: 20207973 Agreement for Detecting Glaucoma Progression with the GDx Guided Progression Analysis, Automated Perimetry, and Optic Disc Photography Ophthalmology. Mar, 2010 | Pubmed ID: 20036010 Cataract Surgery and Glaucoma Current Opinion in Ophthalmology. Jan, 2010 | Pubmed ID: 19829115 Patterns of Glaucomatous Visual Field Loss in Sita Fields Automatically Identified Using Independent Component Analysis Transactions of the American Ophthalmological Society. Dec, 2009 | Pubmed ID: 20126490 Prediction of Functional Loss in Glaucoma from Progressive Optic Disc Damage Archives of Ophthalmology (Chicago, Ill. : 1960). Oct, 2009 | Pubmed ID: 19822839 Outflow Facility in Mice with a Targeted Type I Collagen Mutation Investigative Ophthalmology & Visual Science. Dec, 2009 | Pubmed ID: 19797236 Partitioning of the Aqueous Outflow in Rat Eyes Investigative Ophthalmology & Visual Science. Dec, 2009 | Pubmed ID: 19797235 Reproducibility of RTVue Retinal Nerve Fiber Layer Thickness and Optic Disc Measurements and Agreement with Stratus Optical Coherence Tomography Measurements American Journal of Ophthalmology. Jun, 2009 | Pubmed ID: 19268891 Intraocular Pressure Measurements Throughout the 24 H Current Opinion in Ophthalmology. Mar, 2009 | Pubmed ID: 19240539 Relationship of the 24-hour Pattern of Intraocular Pressure with Optic Disc Appearance in Primary Open-angle Glaucoma Ophthalmology. May, 2009 | Pubmed ID: 19195707 Elevated Hydrostatic Pressure Triggers Release of OPA1 and Cytochrome C, and Induces Apoptotic Cell Death in Differentiated RGC-5 Cells Molecular Vision. 2009 | Pubmed ID: 19169378 Clinicians Agreement in Establishing Glaucomatous Progression Using the Heidelberg Retina Tomograph Ophthalmology. Jan, 2009 | Pubmed ID: 19010552 Memantine Blocks Mitochondrial OPA1 and Cytochrome C Release and Subsequent Apoptotic Cell Death in Glaucomatous Retina Investigative Ophthalmology & Visual Science. Feb, 2009 | Pubmed ID: 18936150 Glutamate Receptor Activation Triggers OPA1 Release and Induces Apoptotic Cell Death in Ischemic Rat Retina Molecular Vision. 2008 | Pubmed ID: 19122832 Relationships Among Systemic Blood Pressure, Intraocular Pressure, and Open-angle Glaucoma Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. Jun, 2008 | Pubmed ID: 18493272 Intraocular Pressure Elevation Induces Mitochondrial Fission and Triggers OPA1 Release in Glaucomatous Optic Nerve Investigative Ophthalmology & Visual Science. Nov, 2008 | Pubmed ID: 18469184 Longitudinal Profile of Retinal Ganglion Cell Damage After Optic Nerve Crush with Blue-light Confocal Scanning Laser Ophthalmoscopy Investigative Ophthalmology & Visual Science. Nov, 2008 | Pubmed ID: 18441315 Comparison of HRT-3 Glaucoma Probability Score and Subjective Stereophotograph Assessment for Prediction of Progression in Glaucoma Investigative Ophthalmology & Visual Science. May, 2008 | Pubmed ID: 18436823 Effect on Diurnal Intraocular Pressure Variation of Eliminating the Alpha-2 Adrenergic Receptor Subtypes in the Mouse Investigative Ophthalmology & Visual Science. Mar, 2008 | Pubmed ID: 18326714 Endoresection of Irradiated Choroidal Melanoma As a Treatment for Intractable Vitreous Hemorrhage and Secondary Blood-induced Glaucoma Seminars in Ophthalmology. Mar-Apr, 2008 | Pubmed ID: 18320480 Long-term Intraocular Pressure Fluctuations and Risk of Conversion from Ocular Hypertension to Glaucoma Ophthalmology. Jun, 2008 | Pubmed ID: 17936908 Reproducibility of Visual Field End Point Criteria for Standard Automated Perimetry, Full-threshold, and Swedish Interactive Thresholding Algorithm Strategies: Diagnostic Innovations in Glaucoma Study American Journal of Ophthalmology. Dec, 2007 | Pubmed ID: 17919445 Oxidative Stress is an Early Event in Hydrostatic Pressure Induced Retinal Ganglion Cell Damage Investigative Ophthalmology & Visual Science. Oct, 2007 | Pubmed ID: 17898281 Effect on Intraocular Pressure of Extraocular Muscle Surgery for Thyroid-associated Ophthalmopathy American Journal of Ophthalmology. Nov, 2007 | Pubmed ID: 17870046 Elevated Hydrostatic Pressure Triggers Mitochondrial Fission and Decreases Cellular ATP in Differentiated RGC-5 Cells Investigative Ophthalmology & Visual Science. May, 2007 | Pubmed ID: 17460273 Sympathetic Activities Influence Blood-flow Velocity and Resistance in the Rabbit Ophthalmic Artery Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Apr, 2007 | Pubmed ID: 17444798 Resistance to Blood Flow in the Rabbit Ophthalmic Artery After Topical Treatment with Timolol Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Apr, 2007 | Pubmed ID: 17444797 Direct Matrix Metalloproteinase Enhancement of Transscleral Permeability Investigative Ophthalmology & Visual Science. Feb, 2007 | Pubmed ID: 17251474 Relationship Between Patterns of Visual Field Loss and Retinal Nerve Fiber Layer Thickness Measurements American Journal of Ophthalmology. Mar, 2006 | Pubmed ID: 16490491 Comparison of Invasive and Non-invasive Tonometry in the Mouse Experimental Eye Research. Jun, 2006 | Pubmed ID: 16466714 Asymmetry of Right Versus Left Intraocular Pressures over 24 Hours in Glaucoma Patients Ophthalmology. Mar, 2006 | Pubmed ID: 16406537 Effect of Bimatoprost on Intraocular Pressure in Prostaglandin FP Receptor Knockout Mice Investigative Ophthalmology & Visual Science. Dec, 2005 | Pubmed ID: 16303950 Baseline Topographic Optic Disc Measurements Are Associated with the Development of Primary Open-angle Glaucoma: the Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study Archives of Ophthalmology (Chicago, Ill. : 1960). Sep, 2005 | Pubmed ID: 16157798 Elevated Intraocular Pressure and Transgenic Applications in the Mouse Journal of Glaucoma. Aug, 2005 | Pubmed ID: 15990617 The Importance of Models in Glaucoma Research Journal of Glaucoma. Aug, 2005 | Pubmed ID: 15990612 Use of Progressive Glaucomatous Optic Disk Change As the Reference Standard for Evaluation of Diagnostic Tests in Glaucoma American Journal of Ophthalmology. Jun, 2005 | Pubmed ID: 15953430 Glaucoma Medication and Aqueous Humor Dynamics Current Opinion in Ophthalmology. Apr, 2005 | Pubmed ID: 15744139 Argon Laser Iridoplasty in the Treatment of Plateau-like Iris Configuration As Result of Numerous Ciliary Body Cysts American Journal of Ophthalmology. Feb, 2005 | Pubmed ID: 15734017 Relationship Between Central Corneal Thickness and Retinal Nerve Fiber Layer Thickness in Ocular Hypertensive Patients Ophthalmology. Feb, 2005 | Pubmed ID: 15691559 Prostaglandin FP Agonists Alter Metalloproteinase Gene Expression in Sclera Investigative Ophthalmology & Visual Science. Dec, 2004 | Pubmed ID: 15557445 Regional Optic Nerve Damage in Experimental Mouse Glaucoma Investigative Ophthalmology & Visual Science. Dec, 2004 | Pubmed ID: 15557443 Effect of Latanoprost on Intraocular Pressure in Mice Lacking the Prostaglandin FP Receptor Investigative Ophthalmology & Visual Science. Oct, 2004 | Pubmed ID: 15452062 Risk Assessment in the Management of Patients with Ocular Hypertension American Journal of Ophthalmology. Sep, 2004 | Pubmed ID: 15364230 Comparison of the Nocturnal Effects of Once-daily Timolol and Latanoprost on Intraocular Pressure American Journal of Ophthalmology. Sep, 2004 | Pubmed ID: 15364220 Using Unsupervised Learning with Variational Bayesian Mixture of Factor Analysis to Identify Patterns of Glaucomatous Visual Field Defects Investigative Ophthalmology & Visual Science. Aug, 2004 | Pubmed ID: 15277482 Confocal Scanning Laser Ophthalmoscopy Classifiers and Stereophotograph Evaluation for Prediction of Visual Field Abnormalities in Glaucoma-suspect Eyes Investigative Ophthalmology & Visual Science. Jul, 2004 | Pubmed ID: 15223803 Effect of Latanoprost on Outflow Facility in the Mouse Investigative Ophthalmology & Visual Science. Jul, 2004 | Pubmed ID: 15223801 Optic Nerve Damage in Mice with a Targeted Type I Collagen Mutation Investigative Ophthalmology & Visual Science. Jun, 2004 | Pubmed ID: 15161848 Primary Open-angle Glaucoma Lancet. May, 2004 | Pubmed ID: 15158634 Comparison of Scanning Laser Polarimetry Using Variable Corneal Compensation and Retinal Nerve Fiber Layer Photography for Detection of Glaucoma Archives of Ophthalmology (Chicago, Ill. : 1960). May, 2004 | Pubmed ID: 15136317 Frequency Doubling Technology Perimetry Abnormalities As Predictors of Glaucomatous Visual Field Loss American Journal of Ophthalmology. May, 2004 | Pubmed ID: 15126151 Influence of Molecular Weight on Intracameral Dextran Movement to the Posterior Segment of the Mouse Eye Investigative Ophthalmology & Visual Science. Feb, 2004 | Pubmed ID: 14744888 Episcleral Venous Pressure of Mouse Eye and Effect of Body Position Current Eye Research. Dec, 2003 | Pubmed ID: 14704919 Aqueous Humor Dynamics in Mice Investigative Ophthalmology & Visual Science. Dec, 2003 | Pubmed ID: 14638713 Twenty-four-hour Pattern of Mouse Intraocular Pressure Experimental Eye Research. Dec, 2003 | Pubmed ID: 14609556 Corneal Thickness Measurements and Frequency Doubling Technology Perimetry Abnormalities in Ocular Hypertensive Eyes Ophthalmology. Oct, 2003 | Pubmed ID: 14522761 Evaluating Several Sources of Variability for Standard and SWAP Visual Fields in Glaucoma Patients, Suspects, and Normals Ophthalmology. Oct, 2003 | Pubmed ID: 14522760 Optic Nerve Damage in Experimental Mouse Ocular Hypertension Investigative Ophthalmology & Visual Science. Oct, 2003 | Pubmed ID: 14507876 Experimental Mouse Ocular Hypertension: Establishment of the Model Investigative Ophthalmology & Visual Science. Oct, 2003 | Pubmed ID: 14507875 Sheath-Preserving Optic Nerve Transection in Rats to Assess Axon Regeneration and Interventions Targeting the Retinal Ganglion Cell Axon Jiun L. Do1, Salam Allahwerdy1, Ryan C. David1, Robert N. Weinreb1, Derek S. Welsbie1 1Hamilton Glaucoma Center, Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California San Diego JoVE 61748 Neuroscience
Sheath-Preserving Optic Nerve Transection in Rats to Assess Axon Regeneration and Interventions Targeting the Retinal Ganglion Cell Axon Jiun L. Do1, Salam Allahwerdy1, Ryan C. David1, Robert N. Weinreb1, Derek S. Welsbie1 1Hamilton Glaucoma Center, Viterbi Family Department of Ophthalmology, Shiley Eye Institute, University of California San Diego JoVE 61748 Neuroscience