Ryan C. Riddle

Publications

• VascuViz: a Multimodality and Multiscale Imaging and Visualization Pipeline for Vascular Systems Biology
  Nature Methods. 02, 2022  |   Pubmed ID: 35145319
• 3D-printed Oxygen-releasing Scaffolds Improve Bone Regeneration in Mice
  Biomaterials. 01, 2022  |   Pubmed ID: 34922272
• Cellular and Tissue Crosstalk in Musculoskeletal Development
  Seminars in Cell & Developmental Biology. 03, 2022  |   Pubmed ID: 34764024
• Bone-derived Sclerostin and Wnt/β-catenin Signaling Regulate PDGFRα Adipoprogenitor Cell Differentiation
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 11, 2021  |   Pubmed ID: 34606641
• Maternal High-Fat Diet Induces Long-Lasting Defects in Bone Structure in Rat Offspring Through Enhanced Osteoclastogenesis
  Calcified Tissue International. 05, 2021  |   Pubmed ID: 33386478
• Dual Effects of Lipid Metabolism on Osteoblast Function
  Frontiers in Endocrinology. 2020  |   Pubmed ID: 33071983
• Preclinical Single Photon Emission Computed Tomography of Alpha Particle-Emitting Radium-223
  Cancer Biotherapy & Radiopharmaceuticals. Sep, 2020  |   Pubmed ID: 32182119
• Frizzled-4 is Required for Normal Bone Acquisition Despite Compensation by Frizzled-8
  Journal of Cellular Physiology. 10, 2020  |   Pubmed ID: 31985040
• CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing
  Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 05, 2020  |   Pubmed ID: 31808575
• Precocious Chondrocyte Differentiation Disrupts Skeletal Growth in Kabuki Syndrome Mice
  JCI Insight. 10, 2019  |   Pubmed ID: 31557133
• The Role of Osteoblasts in Energy Homeostasis
  Nature Reviews. Endocrinology. 11, 2019  |   Pubmed ID: 31462768
• Heparin-Conjugated Decellularized Bone Particles Promote Enhanced Osteogenic Signaling of PDGF-BB to Adipose-Derived Stem Cells in Tissue Engineered Bone Grafts
  Advanced Healthcare Materials. 05, 2019  |   Pubmed ID: 30941920
• Lrp4 Expression by Adipocytes and Osteoblasts Differentially Impacts Sclerostin's Endocrine Effects on Body Composition and Glucose Metabolism
  The Journal of Biological Chemistry. 04, 2019  |   Pubmed ID: 30842262
• Regulation of Osteoblast Metabolism by Wnt Signaling
  Endocrinology and Metabolism (Seoul, Korea). Sep, 2018  |   Pubmed ID: 30112869
• β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice
  Endocrinology. 01, 2018  |   Pubmed ID: 29077850
• Fatty Acid Metabolism by the Osteoblast
  Bone. 10, 2018  |   Pubmed ID: 28863948
• Sclerostin Influences Body Composition by Regulating Catabolic and Anabolic Metabolism in Adipocytes
  Proceedings of the National Academy of Sciences of the United States of America. 12, 2017  |   Pubmed ID: 29229807
• Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism
  Endocrinology. 11, 2017  |   Pubmed ID: 28938444
• Fatty Acid Oxidation by the Osteoblast is Required for Normal Bone Acquisition in a Sex- and Diet-dependent Manner
  JCI Insight. Aug, 2017  |   Pubmed ID: 28814665
• Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance
  Cell Reports. 07, 2017  |   Pubmed ID: 28723568
• Ectopic Calcification in Pseudoxanthoma Elasticum Responds to Inhibition of Tissue-nonspecific Alkaline Phosphatase
  Science Translational Medicine. 06, 2017  |   Pubmed ID: 28592560
• Glucose Transporter-4 Facilitates Insulin-Stimulated Glucose Uptake in Osteoblasts
  Endocrinology. Nov, 2016  |   Pubmed ID: 27689415
• In Vivo Radiometric Analysis of Glucose Uptake and Distribution in Mouse Bone
  Bone Research. 2016  |   Pubmed ID: 27088042
• Whole-Body and Microenvironmental Localization of Radium-223 in Naïve and Mouse Models of Prostate Cancer Metastasis
  Journal of the National Cancer Institute. May, 2016  |   Pubmed ID: 26683407
• New Insights into the Biology of Osteocalcin
  Bone. Jan, 2016  |   Pubmed ID: 26055108
• Parathyroid Hormone Reprograms Osteoblast Metabolism
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Nov, 2015  |   Pubmed ID: 26448640
• Wnt-Lrp5 Signaling Regulates Fatty Acid Metabolism in the Osteoblast
  Molecular and Cellular Biology. Jun, 2015  |   Pubmed ID: 25802278
• Bone and the Regulation of Global Energy Balance
  Journal of Internal Medicine. Jun, 2015  |   Pubmed ID: 25597336
• Osteoblast Menin Regulates Bone Mass in Vivo
  The Journal of Biological Chemistry. Feb, 2015  |   Pubmed ID: 25538250
• Hypoxia-inducible Factor-1α Restricts the Anabolic Actions of Parathyroid Hormone
  Bone Research. 2014  |   Pubmed ID: 26273518
• Insulin, Osteoblasts, and Energy Metabolism: Why Bone Counts Calories
  The Journal of Clinical Investigation. Apr, 2014  |   Pubmed ID: 24642463
• Tsc2 is a Molecular Checkpoint Controlling Osteoblast Development and Glucose Homeostasis
  Molecular and Cellular Biology. May, 2014  |   Pubmed ID: 24591652
• Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts During Postnatal Bone Acquisition
  PloS One. 2013  |   Pubmed ID: 23675479
• BRMS1 Sensitizes Breast Cancer Cells to ATP-Induced Growth Suppression
  BioResearch Open Access. Apr, 2013  |   Pubmed ID: 23593560
• A Mouse Model for Human Osteogenesis Imperfecta Type VI
  Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2013  |   Pubmed ID: 23413146
• Hypoxia-inducible Factor-1α Protein Negatively Regulates Load-induced Bone Formation
  The Journal of Biological Chemistry. Dec, 2011  |   Pubmed ID: 22081627
• Distinct Growth Hormone Receptor Signaling Modes Regulate Skeletal Muscle Development and Insulin Sensitivity in Mice
  The Journal of Clinical Investigation. Nov, 2010  |   Pubmed ID: 20921627
• Roles of Vessel Growth Factors in Bone Development and Repair
  Joint Bone Spine. Dec, 2010  |   Pubmed ID: 20851027
• Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition
  Cell. Jul, 2010  |   Pubmed ID: 20655471
• Role of HIF-1alpha in Skeletal Development
  Annals of the New York Academy of Sciences. Mar, 2010  |   Pubmed ID: 20392254