Silvia C. Finnemann

Publications

• Understanding Photoreceptor Outer Segment Phagocytosis: Use and Utility of RPE Cells in Culture
  Experimental Eye Research. Sep, 2014  |   Pubmed ID: 24780752
• Lack of Effect of Microfilament or Microtubule Cytoskeleton-disrupting Agents on Restriction of Externalized Phosphatidylserine to Rod Photoreceptor Outer Segment Tips
  Advances in Experimental Medicine and Biology. 2014  |   Pubmed ID: 24664685
• Independent Roles of Methionine Sulfoxide Reductase A in Mitochondrial ATP Synthesis and As Antioxidant in Retinal Pigment Epithelial Cells
  Free Radical Biology & Medicine. Dec, 2013  |   Pubmed ID: 24120970
• PI 3-kinase Independent Role for AKT in F-actin Regulation During Outer Segment Phagocytosis by RPE Cells
  Experimental Eye Research. Aug, 2013  |   Pubmed ID: 23669303
• Analysis of Photoreceptor Outer Segment Phagocytosis by RPE Cells in Culture
  Methods in Molecular Biology (Clifton, N.J.). 2013  |   Pubmed ID: 23150376
• Analysis of Photoreceptor Rod Outer Segment Phagocytosis by RPE Cells in Situ
  Methods in Molecular Biology (Clifton, N.J.). 2013  |   Pubmed ID: 23150373
• Diurnal, Localized Exposure of Phosphatidylserine by Rod Outer Segment Tips in Wild-type but Not Itgb5-/- or Mfge8-/- Mouse Retina
  Proceedings of the National Academy of Sciences of the United States of America. May, 2012  |   Pubmed ID: 22566632
• Las Células Epiteliales Del Pigmento Retiniano Utilizan Un Mecanismo Dependiente De MerTK Para Limitar La Actividad Fagocítica De La Partícula De Integrina αvβ5
  Biology of the Cell / Under the Auspices of the European Cell Biology Organization. Jan, 2012  |   Pubmed ID: 22289110
• Essential Diurnal Rac1 Activation During Retinal Phagocytosis Requires αvβ5 Integrin but Not Tyrosine Kinases Focal Adhesion Kinase or Mer Tyrosine Kinase
  Molecular Biology of the Cell. Mar, 2012  |   Pubmed ID: 22262456
• αvβ5 Integrin-dependent Diurnal Phagocytosis of Shed Photoreceptor Outer Segments by RPE Cells is Independent of the Integrin Coreceptor Transglutaminase-2
  Advances in Experimental Medicine and Biology. 2012  |   Pubmed ID: 22183400
• Expression of the Integrin Coreceptor Transglutaminase-2 in the RPE in Vivo and in Culture
  Advances in Experimental Medicine and Biology. 2012  |   Pubmed ID: 22183397
• Dietary Antioxidants Prevent Age-related Retinal Pigment Epithelium Actin Damage and Blindness in Mice Lacking αvβ5 Integrin
  Free Radical Biology & Medicine. Feb, 2012  |   Pubmed ID: 22178979
• Neural Retina and MerTK-independent Apical Polarity of Alphavbeta5 Integrin Receptors in the Retinal Pigment Epithelium
  Advances in Experimental Medicine and Biology. 2010  |   Pubmed ID: 20238010
• The Age Lipid A2E and Mitochondrial Dysfunction Synergistically Impair Phagocytosis by Retinal Pigment Epithelial Cells
  The Journal of Biological Chemistry. Sep, 2008  |   Pubmed ID: 18621729
• Lack of Alphavbeta5 Integrin Receptor or Its Ligand MFG-E8: Distinct Effects on Retinal Function
  Ophthalmic Research. 2008  |   Pubmed ID: 18421224
• Alphavbeta5 Integrin Receptors at the Apical Surface of the RPE: One Receptor, Two Functions
  Advances in Experimental Medicine and Biology. 2008  |   Pubmed ID: 18188966
• Tetraspanin CD81 is Required for the Alpha V Beta5-integrin-dependent Particle-binding Step of RPE Phagocytosis
  Journal of Cell Science. Sep, 2007  |   Pubmed ID: 17684062
• Essential Role for MFG-E8 As Ligand for Alphavbeta5 Integrin in Diurnal Retinal Phagocytosis
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007  |   Pubmed ID: 17620600
• The Lipofuscin Fluorophore A2E Perturbs Cholesterol Metabolism in Retinal Pigment Epithelial Cells
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2007  |   Pubmed ID: 17578916
• MerTK Activation During RPE Phagocytosis in Vivo Requires AlphaVbeta5 Integrin
  Advances in Experimental Medicine and Biology. 2006  |   Pubmed ID: 17249615
• Altered Rhythm of Photoreceptor Outer Segment Phagocytosis in Beta5 Integrin Knockout Mice
  Advances in Experimental Medicine and Biology. 2006  |   Pubmed ID: 17249564
• Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment Epithelium: a Potential Mechanism for Modulating Outer Segment Phagocytosis Under Oxidant Stress Conditions
  The Journal of Biological Chemistry. Feb, 2006  |   Pubmed ID: 16354659
• Novel Role for Alphavbeta5-integrin in Retinal Adhesion and Its Diurnal Peak
  American Journal of Physiology. Cell Physiology. Apr, 2006  |   Pubmed ID: 16338970
• Nonsynaptic Localization of the Excitatory Amino Acid Transporter 4 in Photoreceptors
  Molecular and Cellular Neurosciences. Mar, 2005  |   Pubmed ID: 15737735
• Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking Alphavbeta5 Integrin
  The Journal of Experimental Medicine. Dec, 2004  |   Pubmed ID: 15596525
• Changes in Retinal Pigment Epithelial Gene Expression Induced by Rod Outer Segment Uptake
  Investigative Ophthalmology & Visual Science. Jul, 2004  |   Pubmed ID: 15223782
• Comment on 'Integrin Alphavbbeta is Not Required for the Phagocytosis of Photoreceptor Outer Segments by Cultured Retinal Pigment Epithelial Cells' by M.O. Hall, T.A. Abrams and B.L. Burgess [Exp. Eye Res. 77 (2003) 281-286]
  Experimental Eye Research. Feb, 2004  |   Pubmed ID: 14729363
• Role of Alphavbeta5 Integrin in Regulating Phagocytosis by the Retinal Pigment Epithelium
  Advances in Experimental Medicine and Biology. 2003  |   Pubmed ID: 15180282
• Focal Adhesion Kinase Signaling Promotes Phagocytosis of Integrin-bound Photoreceptors
  The EMBO Journal. Aug, 2003  |   Pubmed ID: 12912913
• The Lipofuscin Component A2E Selectively Inhibits Phagolysosomal Degradation of Photoreceptor Phospholipid by the Retinal Pigment Epithelium
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002  |   Pubmed ID: 11904436