Silvia C. Finnemann

Department of Biological Sciences, Fordham University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 62	2014

Other Publications

Article	Year
The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11904436	2002
Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors. The EMBO journal\| PubMed ID: 12912913	2003
Comment on 'Integrin alphavbbeta is not required for the phagocytosis of photoreceptor outer segments by cultured retinal pigment epithelial cells' by M.O. Hall, T.A. Abrams and B.L. Burgess... Experimental eye research\| PubMed ID: 14729363	2004
Role of alphavbeta5 integrin in regulating phagocytosis by the retinal pigment epithelium. Advances in experimental medicine and biology\| PubMed ID: 15180282	2003
Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake. Investigative ophthalmology & visual science\| PubMed ID: 15223782	2004
Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. The Journal of experimental medicine\| PubMed ID: 15596525	2004
Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors. Molecular and cellular neurosciences\| PubMed ID: 15737735	2005
Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak. American journal of physiology. Cell physiology\| PubMed ID: 16338970	2006
Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating oute... The Journal of biological chemistry\| PubMed ID: 16354659	2006
Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice. Advances in experimental medicine and biology\| PubMed ID: 17249564	2006
MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin. Advances in experimental medicine and biology\| PubMed ID: 17249615	2006
The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17578916	2007
Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17620600	2007
Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis. Journal of cell science\| PubMed ID: 17684062	2007
Alphavbeta5 integrin receptors at the apical surface of the RPE: one receptor, two functions. Advances in experimental medicine and biology\| PubMed ID: 18188966	2008
Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function. Ophthalmic research\| PubMed ID: 18421224	2008
The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells. The Journal of biological chemistry\| PubMed ID: 18621729	2008
Neural retina and MerTK-independent apical polarity of alphavbeta5 integrin receptors in the retinal pigment epithelium. Advances in experimental medicine and biology\| PubMed ID: 20238010	2010
Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin. Free radical biology & medicine\| PubMed ID: 22178979	2012
Expression of the integrin coreceptor transglutaminase-2 in the RPE in vivo and in culture. Advances in experimental medicine and biology\| PubMed ID: 22183397	2012
αvβ5 integrin-dependent diurnal phagocytosis of shed photoreceptor outer segments by RPE cells is independent of the integrin coreceptor transglutaminase-2. Advances in experimental medicine and biology\| PubMed ID: 22183400	2012
Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase. Molecular biology of the cell\| PubMed ID: 22262456	2012
Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of Î±vÎ²5 integrin. Biology of the cell / under the auspices of the European Cell Biology Organization\| PubMed ID: 22289110	2012
Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22566632	2012
Analysis of photoreceptor rod outer segment phagocytosis by RPE cells in situ. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23150373	2013
Analysis of photoreceptor outer segment phagocytosis by RPE cells in culture. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23150376	2013
PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells. Experimental eye research\| PubMed ID: 23669303	2013
Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells. Free radical biology & medicine\| PubMed ID: 24120970	2013
Lack of effect of microfilament or microtubule cytoskeleton-disrupting agents on restriction of externalized phosphatidylserine to rod photoreceptor outer segment tips. Advances in experimental medicine and biology\| PubMed ID: 24664685	2014
Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture. Experimental eye research\| PubMed ID: 24780752	2014