Thomas M. Wishart

Division of Neurobiology, University of Edinburgh

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 50	2014

Other Publications

Article	Year
Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation. The European journal of neuroscience\| PubMed ID: 15579164	2004
The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. Molecular biology of the cell\| PubMed ID: 16371511	2006
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Human molecular genetics\| PubMed ID: 16403805	2006
Delayed synaptic degeneration in the CNS of Wlds mice after cortical lesion. Brain : a journal of neurology\| PubMed ID: 16738060	2006
Synaptic vulnerability in neurodegenerative disease. Journal of neuropathology and experimental neurology\| PubMed ID: 16896307	2006
Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wl... Molecular & cellular proteomics : MCP\| PubMed ID: 17470424	2007
Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene. Molecular neurodegeneration\| PubMed ID: 17971231	2007
VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S). Molecular and cellular neurosciences\| PubMed ID: 18468455	2008
Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds). Genome biology\| PubMed ID: 18570652	2008
Loss of translation elongation factor (eEF1A2) expression in vivo differentiates between Wallerian degeneration and dying-back neuronal pathology. Journal of anatomy\| PubMed ID: 19094180	2008
Protein product of CLN6 gene responsible for variant late-onset infantile neuronal ceroid lipofuscinosis interacts with CRMP-2. Journal of neuroscience research\| PubMed ID: 19235893	2009
Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease. Human molecular genetics\| PubMed ID: 19640925	2009
Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues. BMC neuroscience\| PubMed ID: 20015399	2009
SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy. Human molecular genetics\| PubMed ID: 20705736	2010
Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose. PloS one\| PubMed ID: 21124744	2010
Induction of cell stress in neurons from transgenic mice expressing yellow fluorescent protein: implications for neurodegeneration research. PloS one\| PubMed ID: 21408118	2011
ApoE isoform-specific regulation of regeneration in the peripheral nervous system. Human molecular genetics\| PubMed ID: 21478199	2011
Reversible molecular pathology of skeletal muscle in spinal muscular atrophy. Human molecular genetics\| PubMed ID: 21840928	2011
Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality? Journal of anatomy\| PubMed ID: 22133357	2012
WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering. Current biology : CB\| PubMed ID: 22425157	2012
Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo. PLoS genetics\| PubMed ID: 22952455	2012
Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting. PloS one\| PubMed ID: 24023619	2013
Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy. Genome medicine\| PubMed ID: 24134804	2013
Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. The Journal of clinical investigation\| PubMed ID: 24590288	2014
A novel mouse model of Warburg Micro Syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton. Disease models & mechanisms\| PubMed ID: 24764192	2014
The rat striatum responds to nigro-striatal degeneration via the increased expression of proteins associated with growth and regeneration of neuronal circuitry. Proteome science\| PubMed ID: 24834013	2014
Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target. Neuropathology and applied neurobiology\| PubMed ID: 25041530	2014
Label-free quantitative proteomic profiling identifies disruption of ubiquitin homeostasis as a key driver of schwann cell defects in spinal muscular atrophy. Journal of proteome research\| PubMed ID: 25151848	2014
Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25232125	2014