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Avian Embryonic Left Atrial Ligation Model for HLHS and Cardiovascular Research

June 16th, 2023
*1, *1, 2, 1,2
1Department of Biomedical Sciences and Engineering, Koc University, 2Department of Mechanical Engineering, Koc University
* These authors contributed equally

Summary
Automatic Translation

Here, we present a detailed visual protocol for executing the left atrial ligation (LAL) model in the avian embryo. The LAL model alters the intracardiac flow, which changes wall shear stress loading, mimicking hypoplastic left heart syndrome. An approach to overcome the challenges of this difficult microsurgery model is presented.

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