Geneplus-Beijing Institute 1 article published in JoVE Cancer Research Detection of Rare Mutations in CtDNA Using Next Generation Sequencing Xiaoxing Lv1, Meiru Zhao1, Yuting Yi1, Lucheng Zhang1, Yanfang Guan1, Tao Liu1, Ling Yang1, Rongrong Chen1, Jianhui Ma1, Xin Yi1 1Geneplus-Beijing Institute This manuscript describes a technique for detecting mutations of low frequency in ctDNA, ER-Seq. This method is differentiated by its unique use of two-directional error correction, a special background filter, and efficient molecular acquirement.
