Hiroshima Prefectural Hospital 1 article published in JoVE Medicine Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats Jennifer Altomonte1, Kim A. Muñoz-Álvarez2, Katsunori Shinozaki3, Christine Baumgartner4, Georgios Kaissis5, Rickmer Braren5, Oliver Ebert1 1II. Medizinische Klinik, Klinikum rechts der Isar der TU München, 2Department of Nuclear Medicine, Klinikum rechts der Isar der TU München, 3Division of Clinical Oncology, Hiroshima Prefectural Hospital, 4Center for Preclinical Research, Klinikum rechts der Isar der TU München, 5Institute for Diagnostic and Interventional Radiology, Klinikum rechts der Isar der TU München Oncolytic virotherapies are under development as novel therapeutics for the treatment of hepatocellular carcinoma (HCC). Here we describe a method for locoregional therapy of HCC via hepatic arterial administration of oncolytic virus.
