Lausanne University Hospital (CHUV) and University of Lausanne 2 articles published in JoVE Biology Exploring m6A and m5C Epitranscriptomes upon Viral Infection: an Example with HIV Sara Cristinelli1, Paolo Angelino2, Angela Ciuffi1 1Institute of Microbiology, Lausanne University Hospital and University of Lausanne, 2Bioinformatics Core Facility, SIB Swiss Institute of Bioinformatics The role of RNA modifications in viral infections is just starting to be explored and could highlight new viral-host interaction mechanisms. In this work, we provide a pipeline to investigate m6A and m5C RNA modifications in the context of viral infections. Neuroscience Live-imaging of Mitochondrial System in Cultured Astrocytes Jeanne Espourteille1, Valentin Zufferey1, Jean-Honoré Laurent1, Kevin Richetin1 1Department of Psychiatry, Center for Psychiatric Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne This article describes the method for mitochondrial time-lapse imaging of astrocyte cultures equipped with MitoTimer biosensor and the resulting multiparametric analysis of mitochondrial dynamics, mobility, morphology, biogenesis, redox state, and turnover.
