Vifor Pharma Management Ltd 1 article published in JoVE Medicine Dynamic Light Scattering Analysis for the Determination of the Particle Size of Iron-Carbohydrate Complexes Michael Burgert1, Cintia Baptista Marques2, Gerrit Borchard2, Erik Philipp1, Maria Wilhelm1, Amy Alston1, Reinaldo Digigow1 1Vifor Pharma Group, Vifor Pharma Management Ltd, 2Section of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva Dynamic light scattering (DLS) has emerged as a suitable assay for evaluating the particle size and distribution of intravenously administered iron-carbohydrate complexes. However, the protocols lack standardization and need to be modified for each iron-carbohydrate complex analyzed. The present protocol describes the application and special considerations for the analysis of iron sucrose.
