Institute of Evolutionary Biology, CSIC-UPF 1 article published in JoVE Biology Practical Use of RNA Interference: Oral Delivery of Double-stranded RNA in Liposome Carriers for Cockroaches Jia-Hsin Huang1, Yun Liu1, Yu-Hsien Lin1,2,3, Xavier Belles4, How-Jing Lee1 1Department of Entomology, National Taiwan University, 2Biology Centre, Institute of Entomology, Czech Academy of Sciences, 3Faculty of Science, University of South Bohemia, 4Institute of Evolutionary Biology, CSIC-UPF This manuscript demonstrates the depletion of gene expression in the midgut of the German cockroach through oral ingestion of double-stranded RNA encapsulated in liposomes.