Sanofi Pasteur Limited 1 article published in JoVE Biochemistry Differential Scanning Calorimetry — A Method for Assessing the Thermal Stability and Conformation of Protein Antigen Ibrahim B. Durowoju1, Kamaljit S. Bhandal1, Jian Hu1, Bruce Carpick1, Marina Kirkitadze1 1Analytical Research & Development, Sanofi Pasteur Limited Differential scanning calorimetry measures the thermal transition temperature(s) and total heat energy required to denature a protein. Results obtained are used to assess the thermal stability of protein antigens in vaccine formulations.
