Richard L. Roudebush VA Medical Center 3 articles published in JoVE Behavior The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans Bethany L. Stangl1, Nia D. Byrd1, Soundarya Soundararajan1, Martin H. Plawecki2, Sean O’Connor2,3, Vijay A. Ramchandani1 1Human Psychopharmacology Laboratory, Division of Intramural Clinical and Biological Research, NIAAA, 2Dept. of Psychiatry, Indiana University School of Medicine, 3R.L. Roudebush VA Medical Center This study aims to show that the Progressive-Ratio Computer-assisted Alcohol-Infusion System (CAIS) paradigm is a reliable and sensitive method that can be used to examine the motivating properties associated with alcohol self-administration in humans. Behavior The Participant-Reported Implementation Update and Score (PRIUS): A Novel Method for Capturing Implementation-Related Data Over Time Edward J. Miech1,2,3,4,5, Nicholas A. Rattray1,2,3,6, Dawn M. Bravata1,2,3,5, Jennifer Myers1,3, Teresa M. Damush1,2,3,5 1VA Precision Monitoring (PRIS-M) QUERI, Richard L. Roudebush VA Medical Center, 2William M. Tierney Center for Health Services Research, Regenstrief Institute, 3VA Health Services Research & Development Center for Health Information and Communication (CHIC), Richard L. Roudebush VA Medical Center, 4Department of Emergency Medicine, Indiana University School of Medicine, 5Department of Internal Medicine and Geriatrics, Indiana University School of Medicine, 6Department of Anthropology, Indiana University-Purdue University Indianapolis This protocol describes a novel method for collecting and analyzing data related to ongoing implementation called the Participant-Reported Implementation Update and Score (PRIUS). The PRIUS method allows for the efficient and systematic capture of data over time and from multiple viewpoints in healthcare settings. Medicine Facial Nerve Axotomy in Mice: A Model to Study Motoneuron Response to Injury Deborah N. Olmstead1,2, Nichole A. Mesnard-Hoaglin3, Richard J. Batka1,2, Melissa M. Haulcomb1,2, Whitney M. Miller1,2, Kathryn J. Jones1,2 1Anatomy and Cell Biology, Indiana University School of Medicine, 2Research and Development Services, Richard L. Roudebush VA Medical Center, 3Department of Anatomy and Cell Biology, University of Illinois, Chicago We present a surgical protocol detailing how to perform a cut or crush axotomy on the facial nerve in the mouse. The facial nerve axotomy can be employed to study the physiological response to nerve injury and test therapeutic techniques.