SUNY Polytechnic Institute, Colleges of Nanoscale Science and Engineering 1 article published in JoVE Bioengineering Identification of Metal Oxide Nanoparticles in Histological Samples by Enhanced Darkfield Microscopy and Hyperspectral Mapping Gary A. Roth1, Maria del Pilar Sosa Peña1, Nicole M. Neu-Baker1, Sahil Tahiliani1, Sara A. Brenner1 1Nanobioscience Constellation, SUNY Polytechnic Institute, Colleges of Nanoscale Science and Engineering Enhanced darkfield microscopy and hyperspectral imaging with spectral mapping enable screening, localization, and identification of nanoscale materials in histological samples with improved speed and accuracy over traditional methods. The goal of this paper is to provide methods for darkfield imaging and hyperspectral mapping of metal oxide nanoparticles in histological samples.
