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JoVE Journal
Biology

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Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
 
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Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord

Article DOI: 10.3791/1324-v 20:14 min November 20th, 2009
November 20th, 2009

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Summary

Please note that all translations are automatically generated.

Click here for the English version.

Traumatic injury to the spinal cord disrupts communication with the brain. To restore lost connectivity we utilize a peripheral nerve graft to provide a substratum for regenerating fibers in combination with neurotrophic factors and matrix-modulating enzymes to remove inhibitory molecules to promote long distance growth.

Tags

Peripheral Nerve Grafting Matrix Modulation Injured Rat Spinal Cord Traumatic Injury Axon Regeneration Connectivity Restoration Sciatic Nerve Lesion Site Transplantation Neural Tissues Regenerating Axons Autologous Nerve Heterologous Grafts Acute Injury Chronic Injury Chondroitinase T
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