JoVE Journal
Medicine
Medicine
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
Summary
Malignant gliomas constitute a heterogeneous group of highly infiltrative glial neoplasms with distinct clinical and molecular features. Primary orthotopic xenografts recapitulate the histopathological and molecular features of malignant glioma subtypes in preclinical animal models.