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JoVE Journal Bioengineering
Fragility Assessment of Bovine Cortical Bone Using Scratch Tests
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Fragility Assessment of Bovine Cortical Bone Using Scratch Tests

Article DOI: 10.3791/56488-v • 08:36 min • November 30th, 2017
November 30th, 2017 •
1, 1, 1, 1,2
1Department of Civil and Environmental Engineering, University of Illinois at Urbana Champaign, 2Department of Mechanical Science and Engineering, University of Illinois at Urbana Champaign

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Summary
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This study assesses the fracture toughness of bovine cortical bone at the sub-meso levels using microscopic scratch tests. This is an original, objective, rigorous, and reproducible method proposed to probe fracture toughness below the macroscopic scale. Potential applications are studying changes in bone fragility due to diseases like osteoporosis.

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Fragility Assessment Bovine Cortical Bone Scratch Tests Microscopic Scratch Testing Fractured Behavior Mesoscale Biomechanics Fracture Mechanics Biological Tissues Compact Bone Small Specimens Rigorous Reproducible Semi-destructive Force Measurements Depth Measurements Thawing Frozen Femurs Diamond Band Saw Uniform Cross-sectional Area Dissection Kit Soft Tissue Removal Diamond Wafering Blade Wet Conditions Cleaning Specimens Anionic Cleaner Bleach Solution Ultrasonic Cleaner Embed Cortical Bone Specimens Acrylic Resin
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