Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Chemistry / Spatiotemporally Controlled Nuclear Translocation …
JoVE Journal
Chemistry

A subscription to JoVE is required to view this content. Sign in or start your free trial.

JoVE Journal Chemistry
Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags
An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints
Journal (Chemistry)
An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints
PTR-ToF-MS Coupled with an Automated Sampling System and Tailored Data Analysis for Food Studies: Bioprocess Monitoring, Screening and Nose-space Analysis
Journal (Chemistry)
PTR-ToF-MS Coupled with an Automated Sampling System and Tailored Data Analysis for Food Studies: Bioprocess Monitoring, Screening and Nose-space Analysis
 

Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags

Article DOI: 10.3791/58631-v • 10:10 min • January 17th, 2019
January 17th, 2019 •
1, 1, 1, 1,2
1Department of Chemistry and Biotechnology, School of Engineering, University of Tokyo, 2Riken Center for Emergent Matter Science

Chapters

Summary
Automatic Translation

This protocol describes light-triggered nuclear translocation of guests in living cells using caged molecular glue tags. This method is promising for site-selective nuclear-targeting drug delivery.

Tags

Drug Delivery Nuclear Translocation Caged Molecular Glues Photoactivatable Tags Quantum Dot Linked Cage Molecular Glue Synthesis Stock Solution Dibenzocyclooctyne Aseye Functionalized Quantum Dots Amine Functionalized Peg Dilution Dialysis
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter