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Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
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Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface

Article DOI: 10.3791/60572-v • 10:10 min • February 23rd, 2020
February 23rd, 2020 •
1, 2, 3, 2, 5, 3,4, 2, 2, 1, 3,4, 1,2
1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services

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Summary
Automatic Translation

We present a robust, transferable and predictive in vitro exposure system for the screening and monitoring of airborne particles concerning their acute pulmonary cytotoxicity by exposing cultivated human lung cells at the air-liquid interface (ALI).

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Acute Inhalation Toxicity Airborne Particles Cultivated Human Lung Cells Air-liquid Interface In Vitro Exposure System Reduction Of Animal Experiments Radial Aerosol Distribution Homogeneous Distribution Cell Culture Inserts Growth Medium Trypsinization Of Cells Viable Cells Cell Viability A549 Cells Seeding Density
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