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Journal / Developmental Biology / Transuterine Fetal Tracheal Okklusion Modell bei…
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JoVE Journal Developmental Biology
Transuterine Fetal Tracheal Okklusion Modell bei Mäusen
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Transuterine Fetal Tracheal Okklusion Modell bei Mäusen

Article DOI: 10.3791/61772-v • 06:31 min • February 5th, 2021
February 5th, 2021 •
1,2, 3, 1, 1, 3, 1
1The Center for Fetal, Cellular & Molecular Therapy, Cincinnati Fetal Center, Division of Pediatric General and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, 2Department of Pediatric Surgery, Tekirdag Namik Kemal University School of Medicine, 3The Division of Critical Care Medicine, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center

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Verschiedene Tiermodelle der angeborenen zwerchmatischen Hernie und fetalen Trachealverschluss stellen Vor- und Nachteile in Bezug auf ethische Fragen, Kosten, chirurgische Schwierigkeiten, Größe, Überlebensraten und Verfügbarkeit genetischer Werkzeuge dar. Dieses Modell bietet ein neues Werkzeug, um die Auswirkungen von Trachealokklusion und erhöhtem Luminaldruck auf die Lungenentwicklung zu untersuchen.

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Entwicklungsbiologie Ausgabe 168 Fetale Trachealverschluss angeborene Zwerchfellhernie CHAOS Lungenwachstum fetale Lungenentwicklung Mäuse
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