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Journal / Cancer Research / 荧光显微镜用于人肿瘤细胞和肿瘤异种移植小鼠中巨细胞增多介导的ATP内化…
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Cancer Research

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JoVE Journal Cancer Research
荧光显微镜用于人肿瘤细胞和肿瘤异种移植小鼠中巨细胞增多介导的ATP内化
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荧光显微镜用于人肿瘤细胞和肿瘤异种移植小鼠中巨细胞增多介导的ATP内化

Article DOI: 10.3791/62768-v • 08:31 min • June 30th, 2021
June 30th, 2021 •
*1,2,3, *4, 1,5, 4, 1,2,4, 1,2,4, 6, 1,2,4,7
1Department of Biological Sciences, Ohio University, 2Molecular and Cellular Biology Program, Ohio University, 3Neuroscience Program, Ohio University, 4Edison Biotechnology Institute, Ohio University, 5Translational Biomedical Sciences Program, Ohio University, 6Honors Tutorial College, Ohio University, 7Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University
* These authors contributed equally

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我们开发了一种可重复的方法，以可视化具有高细胞分辨率的不可水解荧光三磷酸腺苷（ATP）的内化，ATP替代物。我们使用独立的 体外 和 体内 测定验证了我们的方法 - 人肿瘤细胞系和用人类肿瘤组织异种移植的免疫缺陷小鼠。

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癌症研究，第172期，
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