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Neuroscience

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JoVE Journal Neuroscience
Messung der Glukoseaufnahme in Drosophila-Modellen der TDP-43-Proteinopathie
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Messung der Glukoseaufnahme in Drosophila-Modellen der TDP-43-Proteinopathie

Article DOI: 10.3791/62936-v • 07:07 min • August 3rd, 2021
August 3rd, 2021 •
*1, *1, 1,2, 1,3
1Department of Molecular and Cellular Biology, University of Arizona, Tucson, 2Vollum Institute, Oregon Health and Science University, 3Department of Neuroscience, University of Arizona, Tucson
* These authors contributed equally

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Die Glukoseaufnahme ist in Drosophila-Motoneuronen erhöht, die von der TAR-DNA-bindenden Protein (TDP-43) -Proteinopathie betroffen sind, wie durch einen FRET-basierten, genetisch kodierten Glukosesensor angezeigt.

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Neuroscience Glukosesensor ALS Drosophila,TDP-43 Proteinopathie
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