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Cancer Research

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JoVE Journal Cancer Research
Cultura dos Organoides do Câncer de Bexiga como Ferramentas de Medicina de Precisão
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Cultura dos Organoides do Câncer de Bexiga como Ferramentas de Medicina de Precisão

Article DOI: 10.3791/63192-v • 08:39 min • December 28th, 2021
December 28th, 2021 •
1,2,3,4, 1,2,3,4,5, 1,4, 1,4,5, 1,2, 1,2, 1,2,4, 1,2,3,4, 1,2,3, 1,2, 1,2, 1,2,3,4, *1,2,3,4,5, *1,2,3,4
1School of Biomedical Sciences, Faculty of Health, Queensland University of Technology (QUT) at Translational Research Institute, 2Queensland Bladder Cancer Initiative (QBCI), 3Centre for Personalised Analysis of Cancers (CPAC), 4Australian Prostate Cancer Research Centre - Queensland, 5Department of Urology, Princess Alexandra Hospital
* These authors contributed equally

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Os organoides derivados do paciente (PDOs) são uma ferramenta poderosa na pesquisa de câncer translacional, refletindo tanto a heterogeneidade genética e fenotípica da doença quanto a resposta a terapias anticânculas personalizadas. Aqui, um protocolo consolidado para gerar PDOs de câncer de bexiga primário humano em preparação para a avaliação de análises fenotípicas e respostas medicamentosas é detalhado.

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Pesquisa sobre câncer edição 178
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